An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm

The regulatory role of smooth muscle 22 on the proliferation of aortic smooth muscle cells participates in the development of aortic dissection

(2017) Yudong Sun et al.   JOURNAL OF VASCULAR SURGERY

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

(2016) Dong-chuan Guo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hereditary Influence in Thoracic Aortic Aneurysm and Dissection

(2016) Eric M. Isselbacher et al.   CIRCULATION

In-depth evaluation of commercially available human vascular smooth muscle cells phenotype: Implications for vascular tissue engineering

(2016) Sara B.H. Timraz et al.   EXPERIMENTAL CELL RESEARCH

Vascular Smooth Muscle Cell Phenotypic Changes in Patients With Marfan SyndromeSignificance

(2015) Eva Crosas-Molist et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aortic Disease Presentation and Outcome Associated WithACTA2MutationsCLINICAL PERSPECTIVE

(2015) Ellen S. Regalado et al.   Circulation-Cardiovascular Genetics

Differentiation of mammary tumors and reduction in metastasis uponMalat1lncRNA loss

(2015) Gayatri Arun et al.   GENES & DEVELOPMENT

Mutations in a TGF-β Ligand, TGFB3, Cause Syndromic Aortic Aneurysms and Dissections

(2015) Aida M. Bertoli-Avella et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

(2015) Norihiro Kato et al.   NATURE GENETICS

The extended AT-hook is a novel RNA binding motif

(2015) Michael Filarsky et al.   RNA Biology

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

(2015) Yoshito Yamashiro et al.   Science Signaling

Aortic Disease Presentation and Outcome Associated WithACTA2MutationsCLINICAL PERSPECTIVE

(2015) Ellen S. Regalado et al.   Circulation-Cardiovascular Genetics

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

(2015) Yoshito Yamashiro et al.   Science Signaling

Histone Deacetylase 9 Represses Cholesterol Efflux and Alternatively Activated Macrophages in Atherosclerosis Development

(2014) Qiang Cao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection

(2014) Yang Yuan et al.   BMC Cardiovascular Disorders

Familial thoracic aortic aneurysms

(2014) Guillaume Jondeau et al.   CURRENT OPINION IN CARDIOLOGY

Ascending aorta dilation in association with bicuspid aortic valve: A maturation defect of the aortic wall

(2014) Nimrat Grewal et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7

(2014) Tatiana Foroud et al.   STROKE

The Genetic Basis of Aortic Aneurysm

(2014) M. E. Lindsay et al.   Cold Spring Harbor Perspectives in Medicine

Heritable thoracic aortic disorders

(2013) Reed E. Pyeritz   CURRENT OPINION IN CARDIOLOGY

HDAC9 Knockout Mice Are Protected From Adipose Tissue Dysfunction and Systemic Metabolic Disease During High-Fat Feeding

(2013) T. K. Chatterjee et al.   DIABETES

Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

(2013) Elena M. Gallo et al.   JOURNAL OF CLINICAL INVESTIGATION

Reconstructing dynamic microRNA-regulated interaction networks

(2013) M. H. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

(2012) Mark E Lindsay et al.   NATURE GENETICS

TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome

(2012) Catherine Boileau et al.   NATURE GENETICS

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

(2012) Céline Bellenguez et al.   NATURE GENETICS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult

(2012) Bin Zhang et al.   Cell Reports

Chromatin Isolation by RNA Purification (ChIRP)

(2012) Ci Chu et al.   Jove-Journal of Visualized Experiments

Predicting RNA-Protein Interactions Using Only Sequence Information

(2011) Usha K Muppirala et al.   BMC BIOINFORMATICS

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Histone Deacetylase 9 Is a Negative Regulator of Adipogenic Differentiation

(2011) Tapan K. Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

(2010) Li Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis

(2010) Kiyuk Chang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections

(2010) Sakiko Inamoto et al.   CARDIOVASCULAR RESEARCH

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

Nuclear Speckles

(2010) D. L. Spector et al.   Cold Spring Harbor Perspectives in Biology

Nuclear Functions of Actin

(2010) N. Visa et al.   Cold Spring Harbor Perspectives in Biology

The SWI/SNF Chromatin Remodeling Complex Regulates Myocardin-Induced Smooth Muscle–Specific Gene Expression

(2009) Jiliang Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A proteomic study of the aortic media in human thoracic aortic dissection: Implication for oxidative stress

(2008) Mingfang Liao et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY