A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-01-03
DOI
10.1038/s41467-017-02611-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes
- (2016) Cherie T. Ng et al. CELL
- The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent
- (2016) Kirsten E. Wiens et al. PLoS Pathogens
- IL6 gene allele-specific C/EBPα-binding activity affects the development of HBV infection through modulation of Th17/Treg balance
- (2015) G Zhang et al. GENES AND IMMUNITY
- Interfering with Immunity: Detrimental Role of Type I IFNs during Infection
- (2015) Sebastian A. Stifter et al. JOURNAL OF IMMUNOLOGY
- Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics
- (2014) Anca Dorhoi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
- (2014) Katrin D. Mayer-Barber et al. NATURE
- CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
- (2014) Weiming Wang et al. PLoS One
- Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
- (2013) Nicole A de Weerd et al. NATURE IMMUNOLOGY
- Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers
- (2013) Chloe I. Bloom et al. PLoS One
- Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells
- (2013) Sebastian A. Stifter et al. PROTEIN EXPRESSION AND PURIFICATION
- Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses
- (2013) R. M. B. Teles et al. SCIENCE
- A Functional Single-Nucleotide Polymorphism in the Promoter of the Gene Encoding Interleukin 6 Is Associated With Susceptibility to Tuberculosis
- (2012) Guoliang Zhang et al. JOURNAL OF INFECTIOUS DISEASES
- Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis
- (2012) Tom H. M. Ottenhoff et al. PLoS One
- Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy
- (2012) Chloe I. Bloom et al. PLoS One
- The fundamental role of flexibility on the strength of molecular binding
- (2012) Christopher Forrey et al. Soft Matter
- Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2
- (2011) Rebecca A. R. Piganis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1 Production in Human Macrophages
- (2011) A. Novikov et al. JOURNAL OF IMMUNOLOGY
- An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
- (2010) Matthew P. R. Berry et al. NATURE
- Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1
- (2010) Daniel J. Gough et al. PLOS BIOLOGY
- Diagnosis of Active Tuberculosis in China Using an In-House Gamma Interferon Enzyme-Linked Immunospot Assay
- (2009) X. Chen et al. Clinical and Vaccine Immunology
- Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial
- (2009) Tania Mara Welzel et al. HEPATOLOGY
- Ligand Binding Induces a Conformational Change in ifnar1 that Is Propagated to Its Membrane-Proximal Domain
- (2008) Jennifer Julia Strunk et al. JOURNAL OF MOLECULAR BIOLOGY
- A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection
- (2008) J. Zhou et al. JOURNAL OF VIRAL HEPATITIS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now