PPARγ Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling

The orphan nuclear receptor COUP-TFII coordinates hypoxia-independent proangiogenic responses in hepatic stellate cells

(2017) Elisabetta Ceni et al.   JOURNAL OF HEPATOLOGY

Prolyl oligopeptidase attenuates hepatic stellate cell activation through induction of Smad7 and PPAR-γ

(2017) Da Zhou et al.   Experimental and Therapeutic Medicine

Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis

(2016) Qian Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Liver Fibrosis: From Pathogenesis to Novel Therapies

(2016) Ralf Weiskirchen et al.   DIGESTIVE DISEASES

Activation of autophagy through calcium-dependent AMPK/mTOR and PKCθ pathway causes activation of rat hepatic stellate cells under hypoxic stress

(2016) Yuepeng Jin et al.   FEBS LETTERS

GATA binding protein 3 is correlated with leptin regulation of PPARγ1 in hepatic stellate cells

(2016) Wei Guan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Astaxanthin reduces hepatic lipid accumulations in high-fat-fed C57BL/6J mice via activation of peroxisome proliferator-activated receptor (PPAR) alpha and inhibition of PPAR gamma and Akt

(2016) Yaoyao Jia et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hepatic erythropoietin response in cirrhosis

(2016) Louise M. Risør et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Does pressure cause liver cirrhosis? The sinusoidal pressure hypothesis

(2016) Sebastian Mueller   WORLD JOURNAL OF GASTROENTEROLOGY

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

(2016) H Jin et al.   Cell Death & Disease

Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer

(2016) Mingxing Wang et al.   Oncotarget

Hypoxia-inducible factor-1alpha in hepatic fibrosis: A promising therapeutic target

(2015) Lei Zhan et al.   BIOCHIMIE

Valproic acid protects against haemorrhagic shock-induced signalling changes via PPARγ activation in anin vitromodel

(2015) Alexandra M E Zuckermann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-miR-362-3p Inhibits Migration and Invasion of Human Gastric Cancer Cells by Its Target CD82

(2015) Qing-Hui Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

Receptor channel TRPC6 orchestrate the activation of human hepatic stellate cell under hypoxia condition

(2015) Soumya C Iyer et al.   EXPERIMENTAL CELL RESEARCH

Hepatic inflammation and fibrosis: Functional links and key pathways

(2015) Ekihiro Seki et al.   HEPATOLOGY

Recent advancement of molecular mechanisms of liver fibrosis

(2015) Ekihiro Seki et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Curcumin upregulates Nrf2 nuclear translocation and protects rat hepatic stellate cells against oxidative stress

(2015) ZHENXIONG LIU et al.   Molecular Medicine Reports

Erythropoietin alleviates hepatic insulin resistance via PPARγ-dependent AKT activation

(2015) Zhijuan Ge et al.   Scientific Reports

Early Effects of a Hypocaloric, Mediterranean Diet on Laboratory Parameters in Obese Individuals

(2014) Marta Greco et al.   MEDIATORS OF INFLAMMATION

Hypoxia and Adipose Tissue Function and Dysfunction in Obesity

(2013) Paul Trayhurn   PHYSIOLOGICAL REVIEWS

Hypoxia-Inducible Factor-1alpha and MAPK Co-Regulate Activation of Hepatic Stellate Cells upon Hypoxia Stimulation

(2013) Yueqin Wang et al.   PLoS One

Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedside

(2012) Feng Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Peroxisome Proliferator-Activated Receptor Gamma Exacerbates Concanavalin A-Induced Liver Injury via Suppressing the Translocation of NF-κB into the Nucleus

(2012) Yuji Ogawa et al.   PPAR Research

Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis

(2010) Bryan L. Copple et al.   LIVER INTERNATIONAL

The PPAR-γ agonist rosiglitazone facilitates Akt rephosphorylation and inhibits apoptosis in cardiomyocytes during hypoxia/reoxygenation

(2009) H. Kilter et al.   DIABETES OBESITY & METABOLISM

The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-  (PPAR ) and thiazolidinedione-PPAR  agonists

(2008) V Costa et al.   ENDOCRINE-RELATED CANCER