Do we still need cryoprecipitate? Cryoprecipitate and fibrinogen concentrate as treatments for major hemorrhage — how do they compare?

Fibrinogen is an independent predictor of mortality in major trauma patients: A five-year statewide cohort study

(2017) Zoe K. McQuilten et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Use of factor concentrates for the management of perioperative bleeding: guidance from the SSC of the ISTH

(2017) A. Godier et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

(2017) Haleema Shakur et al.   LANCET

iTACTIC – implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial

(2017) Kjersti Baksaas-Aasen et al.   Trials

Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial

(2017) James Winearls et al.   Trials

Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial

(2017) Petra Innerhofer et al.   Lancet Haematology

Comparing efficacy and safety of fibrinogen concentrate to cryoprecipitate in bleeding patients: a systematic review

(2016) N. H. L. Jensen et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Impact of Preemptive Fibrinogen Concentrate on Transfusion Requirements in Liver Transplantation: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

(2016) A. Sabate et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Fibrinogen in the initial resuscitation of severe trauma (FiiRST): a randomized feasibility trial

(2016) B. Nascimento et al.   BRITISH JOURNAL OF ANAESTHESIA

Mortality from trauma haemorrhage and opportunities for improvement in transfusion practice

(2016) S. J. Stanworth et al.   BRITISH JOURNAL OF SURGERY

Alterations in Fibrin Structure in Patients with Liver Diseases

(2016) Robert Ariëns et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

The hemostatic properties of thawed pooled cryoprecipitate up to 72 hours

(2016) Laura Green et al.   TRANSFUSION

Cryoprecipitate AHF vs. fibrinogen concentrates for fibrinogen replacement in acquired bleeding patients - an economic evaluation

(2016) C. K. Okerberg et al.   VOX SANGUINIS

Early cryoprecipitate for major haemorrhage in trauma: a randomised controlled feasibility trial

(2015) N. Curry et al.   BRITISH JOURNAL OF ANAESTHESIA

Pre-emptive treatment with fibrinogen concentrate for postpartum haemorrhage: randomized controlled trial †

(2015) A.J. Wikkelsø et al.   BRITISH JOURNAL OF ANAESTHESIA

Usefulness of standard plasma coagulation tests in the management of perioperative coagulopathic bleeding: is there any evidence?

(2015) T. Haas et al.   BRITISH JOURNAL OF ANAESTHESIA

A practical guideline for the haematological management of major haemorrhage

(2015) Beverley J. Hunt et al.   BRITISH JOURNAL OF HAEMATOLOGY

Over 50 Years of Fibrinogen Concentrate

(2015) Rubens Costa-Filho et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Fibrinogen concentrate for bleeding - a systematic review

(2014) J. LUNDE et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Cryoprecipitate therapy

(2014) B. Nascimento et al.   BRITISH JOURNAL OF ANAESTHESIA

Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage

(2014) Sirat Khan et al.   Journal of Trauma and Acute Care Surgery

Coagulation management with factor concentrates in liver transplantation: a single-center experience

(2014) Carmen Kirchner et al.   TRANSFUSION

Management of severe perioperative bleeding

(2013) Sibylle A. Kozek-Langenecker et al.   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

When do we transfuse cryoprecipitate?

(2013) M. A. Anderson et al.   INTERNAL MEDICINE JOURNAL

Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy

(2013) Jerrold H. Levy et al.   TRANSFUSION

Judith Graham Pool and the discovery of cryoprecipitate

(2012) C. K. Kasper   HAEMOPHILIA

Fibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomes

(2012) C. ROURKE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The incidence and magnitude of fibrinolytic activation in trauma patients

(2012) I. RAZA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cryoprecipitate for transfusion: which patients receive it and why? A study of patterns of use across three regions in England

(2012) H. Tinegate et al.   TRANSFUSION MEDICINE

Functional definition and characterization of acute traumatic coagulopathy

(2011) Ross Davenport et al.   CRITICAL CARE MEDICINE

The impact of fresh frozen plasma vs coagulation factor concentrates on morbidity and mortality in trauma-associated haemorrhage and massive transfusion

(2011) Ulrike Nienaber et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Assessment of coagulation in the obstetric population using ROTEM® thromboelastometry

(2011) S. Armstrong et al.   INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA

Standard haemostatic tests following major obstetric haemorrhage

(2011) L. de Lloyd et al.   INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA

Clotting Factor Deficiency in Early Trauma-Associated Coagulopathy

(2011) Sandro B. Rizoli et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Blood transfusion and the anaesthetist: management of massive haemorrhage

(2010) D Thomas et al.   ANAESTHESIA

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

(2010)   LANCET

Haemostatic reference intervals in pregnancy

(2010) Maja Jørgensen et al.   THROMBOSIS AND HAEMOSTASIS

Cryoprecipitate use in 25 Canadian hospitals: commonly used outside of the published guidelines

(2008) Edward C. Alport et al.   TRANSFUSION