SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function

Update on molecular findings in rhabdomyosarcoma

(2017) Dina El Demellawy et al.   PATHOLOGY

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma

(2017) Myron S. Ignatius et al.   Cell Reports

Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma

(2017) Inês M Tenente et al.   eLife

Targeting MET Receptor in Rhabdomyosarcoma: Rationale and Progress

(2016) Barbara Szewczyk et al.   CURRENT DRUG TARGETS

Cytoplasmic NOTCH and membrane-derived β-catenin link cell fate choice to epithelial-mesenchymal transition during myogenesis

(2016) Daniel Sieiro et al.   eLife

Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression

(2015) Klaudia Skrzypek et al.   Oncotarget

Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis

(2014) J. Stanisavljevic et al.   CANCER RESEARCH

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Efficient myoblast expansion for regenerative medicine use

(2014) DANUTA JAROCHA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Muscle stem cells at a glance

(2014) Y. X. Wang et al.   JOURNAL OF CELL SCIENCE

Interplay Between Heme Oxygenase-1 and miR-378 Affects Non-Small Cell Lung Carcinoma Growth, Vascularization, and Metastasis

(2013) Klaudia Skrzypek et al.   ANTIOXIDANTS & REDOX SIGNALING

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers

(2013) Jean-Louis Plouhinec et al.   DEVELOPMENTAL BIOLOGY

In Vivo Imaging of Tumor-Propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma

(2012) Myron S. Ignatius et al.   CANCER CELL

Snail Regulates MyoD Binding-Site Occupancy to Direct Enhancer Switching and Differentiation-Specific Transcription in Myogenesis

(2012) Vahab D. Soleimani et al.   MOLECULAR CELL

Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells

(2012) R Batlle et al.   ONCOGENE

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Genome-Wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and Cancer

(2010) L. Cao et al.   CANCER RESEARCH

Muscling in: Uncovering the origins of rhabdomyosarcoma

(2010) Simone Hettmer et al.   NATURE MEDICINE

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

(2010) A Zibat et al.   ONCOGENE

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

(2009) R. Grant Rowe et al.   JOURNAL OF CELL BIOLOGY

Alveolar rhabdomyosarcoma: Is the cell of origin a mesenchymal stem cell?

(2008) Elizabeth Charytonowicz et al.   CANCER LETTERS