STK17B promotes carcinogenesis and metastasis via AKT/GSK-3β/Snail signaling in hepatocellular carcinoma

Discovery of benzofuran-3(2 H )-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis

(2017) Sheng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling

(2017) Yanjiao Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening

(2016) Myoung Eun Jung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

(2016) Lan Wang et al.   GASTROENTEROLOGY

N-myc downstream-regulated gene 2 inhibits human cholangiocarcinoma progression and is regulated by leukemia inhibitory factor/MicroRNA-181c negative feedback pathway

(2016) Jiabei Wang et al.   HEPATOLOGY

MicroRNA-455 regulates migration and invasion of human hepatocellular carcinoma by targeting Runx2

(2016) Le Qin et al.   ONCOLOGY REPORTS

Drak2 is not required for tumor surveillance and suppression

(2015) Benjamin A. Edwards et al.   INTERNATIONAL IMMUNOLOGY

MicroRNA-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting PH domain and leucine-rich repeat protein phosphatase

(2014) Rui-Min Chang et al.   HEPATOLOGY

Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt/GSK-3β/Snail signaling

(2013) Lulu Liu et al.   HEPATOLOGY

The MYB oncogene can suppress apoptosis in acute myeloid leukemia cells by transcriptional repression of DRAK2 expression

(2013) Ping Ye et al.   LEUKEMIA RESEARCH

Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma

(2013) Yoshito Tomimaru et al.   LIVER INTERNATIONAL

miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions

(2012) Ying Chang et al.   GASTROENTEROLOGY

DRAK2 Participates in a Negative Feedback Loop to Control TGF-β/Smads Signaling by Binding to Type I TGF-β Receptor

(2012) Kyung-Min Yang et al.   Cell Reports

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

(2011) Jian-Hong Fang et al.   HEPATOLOGY

Diphenyl Difluoroketone: A Potent Chemotherapy Candidate for Human Hepatocellular Carcinoma

(2011) Yingjian Liang et al.   PLoS One

Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer

(2009) G A Doherty et al.   BRITISH JOURNAL OF CANCER

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Combination of Multiple Molecular Markers Can Improve Prognostication in Patients With Locally Advanced and Lymph Node Positive Bladder Cancer

(2009) Shahrokh F. Shariat et al.   JOURNAL OF UROLOGY

Biology of Hepatocellular Carcinoma

(2008) Roberta W. C. Pang et al.   ANNALS OF SURGICAL ONCOLOGY

Identification of metastasis-related microRNAs in hepatocellular carcinoma

(2008) Anuradha Budhu et al.   HEPATOLOGY

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE

Identification of selectively expressed genes and antigens in CTCL

(2007) Tanja B. Hartmann et al.   EXPERIMENTAL DERMATOLOGY