The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

(2017) Amit A. Patel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cellular senescence impact on immune cell fate and function

(2016) Rita Vicente et al.   AGING CELL

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

(2016) B. G. Childs et al.   SCIENCE

MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8

(2016) Dipa Bhaumik et al.   Aging-US

MicroRNA expression profiling of human blood monocyte subsets highlights functional differences

(2015) Truong-Minh Dang et al.   IMMUNOLOGY

The Role of Different Monocyte Subsets in the Pathogenesis of Atherosclerosis and Acute Coronary Syndromes

(2015) E. Idzkowska et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous

(2015) Ratnadeep Mukherjee et al.   Scientific Reports

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Alterations to the Frequency and Function of Peripheral Blood Monocytes and Associations with Chronic Disease in the Advanced-Age, Frail Elderly

(2014) Chris P. Verschoor et al.   PLoS One

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Accumulation of CD16+Monocytes at Local Sites of Inflammation in Patients with Chronic Kidney Disease

(2013) C. Wallquist et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling

(2012) Fabiola Olivieri et al.   AGE

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function

(2012) Anna C. Hearps et al.   AGING CELL

Monoclonal antibodies against macrophage colony-stimulating factor diminish the number of circulating intermediate and nonclassical (CD14++CD16+/CD14+CD16++) monocytes in rheumatoid arthritis patient

(2012) M. Korkosz et al.   BLOOD

The three human monocyte subsets: implications for health and disease

(2012) Kok Loon Wong et al.   IMMUNOLOGIC RESEARCH

Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling

(2012) S. Rajagopalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages

(2011) C. Cudejko et al.   BLOOD

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets

(2011) K. L. Wong et al.   BLOOD

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

(2011) Antero Salminen et al.   CELLULAR SIGNALLING

Preparations of intravenous immunoglobulins diminish the number and proinflammatory response of CD14+CD16++ monocytes in common variable immunodeficiency (CVID) patients

(2011) Maciej Siedlar et al.   CLINICAL IMMUNOLOGY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Hyper-Activated Pro-Inflammatory CD16+ Monocytes Correlate with the Severity of Liver Injury and Fibrosis in Patients with Chronic Hepatitis B

(2011) Ji-Yuan Zhang et al.   PLoS One

The CD14+/lowCD16+ monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14+CD16− subset

(2011) C Zhao et al.   Cell Death & Disease

Age-associated increase in heterochromatic marks in murine and primate tissues

(2010) Jill A. Kreiling et al.   AGING CELL

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

CD16 (FcRγIII) as a potential marker of osteoclast precursors in psoriatic arthritis

(2010) Yahui Grace Chiu et al.   ARTHRITIS RESEARCH & THERAPY

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

(2009) Petronela Ancuta et al.   BMC GENOMICS

Monocyte heterogeneity in obesity and subclinical atherosclerosis

(2009) K. S. Rogacev et al.   EUROPEAN HEART JOURNAL

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Novel Functional Differences in Monocyte Subsets Using Proteomic and Transcriptomic Methods

(2009) Changqing Zhao et al.   JOURNAL OF PROTEOME RESEARCH

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

(2009) María Pita-Lopez et al.   Immunity & Ageing

Cellular senescence and organismal aging

(2008) Jessie C. Jeyapalan et al.   MECHANISMS OF AGEING AND DEVELOPMENT