The Typhoid Toxin Produced by the Nontyphoidal Salmonella enterica Serotype Javiana Is Required for Induction of a DNA Damage Response In Vitro and Systemic Spread In Vivo

The control of DNA repair by the cell cycle

(2017) Nicole Hustedt et al.   NATURE CELL BIOLOGY

Characterization of pertussis-like toxin from Salmonella spp. that catalyzes ADP-ribosylation of G proteins

(2017) Yukino Tamamura et al.   Scientific Reports

Evolution of host adaptation in the Salmonella typhoid toxin

(2017) Xiang Gao et al.   Nature Microbiology

Animal Models for Salmonellosis: Applications in Vaccine Research

(2016) Ellen E. Higginson et al.   Clinical and Vaccine Immunology

Least-Squares Means: TheRPackagelsmeans

(2016) Russell V. Lenth   Journal of Statistical Software

Typhoid toxin provides a window into typhoid fever and the biology ofSalmonellaTyphi

(2016) Jorge E. Galán   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi

(2016) Rachel A. Miller et al.   mBio

The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection

(2016) Lisa Del Bel Belluz et al.   PLoS Pathogens

Dynamic Duo—The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin

(2016) Rachel Miller et al.   Toxins

Cytotoxic Mechanism ofCytolethal Distending Toxinin NontyphoidalSalmonellaSerovar (SalmonellaJaviana) During Macrophage Infection

(2015) Katherine Williams et al.   DNA AND CELL BIOLOGY

The Flagellar Regulator TviA Reduces Pyroptosis by Salmonella enterica Serovar Typhi

(2015) Sebastian E. Winter et al.   INFECTION AND IMMUNITY

Characterization of the cytolethal distending toxin (typhoid toxin) in non-typhoidal Salmonella serovars

(2015) Lorraine D Rodriguez-Rivera et al.   Gut Pathogens

World Health Organization Estimates of the Global and Regional Disease Burden of 22 Foodborne Bacterial, Protozoal, and Viral Diseases, 2010: A Data Synthesis

(2015) Martyn D. Kirk et al.   PLOS MEDICINE

Salmonella enterica Infections in the United States and Assessment of Coefficients of Variation: A Novel Approach to Identify Epidemiologic Characteristics of Individual Serotypes, 1996–2011

(2015) Amy L. Boore et al.   PLoS One

Host Adaptation of a Bacterial Toxin from the Human Pathogen Salmonella Typhi

(2014) Lingquan Deng et al.   CELL

Salmonella enterica Serovar Typhi Impairs CD4 T Cell Responses by Reducing Antigen Availability

(2014) S. M. Atif et al.   INFECTION AND IMMUNITY

Die another way – non-apoptotic mechanisms of cell death

(2014) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

(2014) Felix Dietlein et al.   TRENDS IN GENETICS

Keeping inflammation at bay

(2014) David Wallach et al.   eLife

Detection and functionality of the CdtB, PltA, and PltB fromSalmonella entericaserovar Javiana

(2014) Ezat H. Mezal et al.   Pathogens and Disease

Salmonella entericadelivers its genotoxin through outer membrane vesicles secreted from infected cells

(2013) Riccardo Guidi et al.   CELLULAR MICROBIOLOGY

Structure and function of the Salmonella Typhi chimaeric A2B5 typhoid toxin

(2013) Jeongmin Song et al.   NATURE

From single-strand breaks to double-strand breaks during S-phase: a new mode of action of theEscherichia coli Cytolethal Distending Toxin

(2012) Y. Fedor et al.   CELLULAR MICROBIOLOGY

A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion

(2012) Hélène Hodak et al.   EMBO REPORTS

Involvement of Toll-like receptor 2 in apoptosis of Aggregatibacter actinomycetemcomitans-infected THP-1 cells

(2012) Satsuki Kato et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Bacterial toxin modulation of the eukaryotic cell cycle: are all cytolethal distending toxins created equally?

(2012) Amandeep Gargi et al.   Frontiers in Cellular and Infection Microbiology

Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica

(2011) Henk C den Bakker et al.   BMC GENOMICS

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

(2011) R. N. Jinadasa et al.   MICROBIOLOGY-SGM

The Global Burden of NontyphoidalSalmonellaGastroenteritis

(2010) Shannon E. Majowicz et al.   CLINICAL INFECTIOUS DISEASES

So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi

(2010) Sébastien C. Sabbagh et al.   FEMS MICROBIOLOGY LETTERS

Helicobacter hepaticusCytolethal Distending Toxin Causes Cell Death in Intestinal Epithelial Cells via Mitochondrial Apoptotic Pathway

(2010) Namal P. M. Liyanage et al.   HELICOBACTER

Role of the ATM-Checkpoint Kinase 2 Pathway in CDT-Mediated Apoptosis of Gingival Epithelial Cells

(2010) Mounia Alaoui-El-Azher et al.   PLoS One

DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints

(2010) Zhongsheng You et al.   TRENDS IN CELL BIOLOGY

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Induces Apoptosis in Nonproliferating Macrophages by a Phosphatase-Independent Mechanism

(2009) S. D. P. Rabin et al.   INFECTION AND IMMUNITY

Perturbation of the Small Intestine Microbial Ecology by Streptomycin Alters Pathology in a Salmonella enterica Serovar Typhimurium Murine Model of Infection

(2009) C. D. Garner et al.   INFECTION AND IMMUNITY

Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

(2009) Hana Blazkova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Delivery of a Salmonella Typhi Exotoxin from a Host Intracellular Compartment

(2008) Stefania Spanò et al.   Cell Host & Microbe

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY