Journal
SEMINARS IN PEDIATRIC NEUROLOGY
Volume 28, Issue -, Pages 60-65Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.spen.2018.05.007
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Funding
- NINDS, United States [R01NS72338, RO1NS060653]
- NICHD, United States [U01HD087180-01]
- June and Steve Wolfson Family Foundation
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS060653] Funding Source: NIH RePORTER
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Infants born with critical congenital heart disease are at risk for neurodevelopmental morbidities later in life. In-utero differences in fetal circulation lead to vulnerabilities which lead to an increased incidence of stroke, white matter injury, and brain immaturity. Recent work has shown these infants may be most vulnerable to brain injury during the early neonatal period when they are awaiting their cardiac surgeries. Novel imaging and monitoring modalities are being employed to investigate this crucial time period and elucidate the precise timing and cause of brain injury in this population. (C) 2018 Elsevier Inc. All rights reserved.
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