Journal
TICKS AND TICK-BORNE DISEASES
Volume 9, Issue 2, Pages 415-417Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.ttbdis.2017.12.008
Keywords
CXCL13; Borrelia burgdorferi; Neuroborreliosis; Cerebrospinal fluid
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We report the case of an 80-year-old patient with acute onset confusion initially suspected to reflect delirium in incipient Alzheimer's disease. Cerebrospinal fluid tests revealed an unusually severe form of neuroborreliosis, which resolved following antibiotic treatment. This was mirrored in the measurement of CXCL13, which is suggested as a complementary biomarker. Clinical implications for screening, differential diagnosis and treatment are discussed.
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