Journal
VIRUSES-BASEL
Volume 10, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/v10040172
Keywords
typhoid fever; Salmonella Typhi; extended-spectrum beta lactamases (ESBL); Democratic Republic of the Congo; bacteriophages
Categories
Funding
- International Science and Technology Center [ISTC-A 2140]
- Science Foundation Ireland [12/R1/2335]
- KU Leuven Orchestrated Research Action
- Fonds Wetenschappelijk Onderzoek Vlaanderen [1S64718N]
- Belgian Directorate of Development Cooperation (DGD) [2.01]
- Baillet-Latour Fund (The Bacterial Infections in the Tropics (BIT) research cluster at ITM Antwerp, Belgium)
- Department of Economy, Science and Innovation in Flanders (EWI funding ITM Antwerp)
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Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum 3-lactamase ( ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.
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