Editorial Material
Infectious Diseases
Kamal Makhoul, Yousef Shukha, Lana Abu Hanna, Samy Nitecki, Maxim Leiderman, Tony Hayek, Shadi Hamoud
Summary: COVID-19 is a disease with multisystemic involvement, caution should be taken with the complications that may lead to arterial and venous thromboembolic events, even resulting in amputation of the affected limbs.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Farina Mohamad Yusoff, Masato Kajikawa, Takayuki Yamaji, Yuji Takaeko, Yu Hashimoto, Aya Mizobuchi, Yiming Han, Shinji Kishimoto, Tatsuya Maruhashi, Ayumu Nakashima, Yukihito Higashi
Summary: The study aimed at evaluating outcomes of CLI patients treated with LIPUS, showing a significant reduction in major amputations and deaths in the LIPUS group compared to historical controls.
Review
Cell & Tissue Engineering
Laura Lozano Navarro, Xueyi Chen, Lady Tatiana Girata Viviescas, Andrea K. Ardila-Roa, Maria L. Luna-Gonzalez, Claudia L. Sossa, Martha L. Arango-Rodriguez
Summary: Peripheral arterial disease affects hundreds of millions of people worldwide and can lead to limb amputation or death. Revascularization is crucial for preventing amputation, but a significant portion of patients are not suitable for traditional surgical treatment, resulting in higher amputation rates. Mesenchymal stem cells have emerged as a promising cell-based therapy for peripheral arterial disease due to their regenerative properties.
STEM CELL RESEARCH & THERAPY
(2022)
Article
Surgery
Chanean Ruangsetakit, Sanit Navikaputra, Kanin Pruekprasert, Tossapol Prapassaro, Nattawut Puangpunngam, Kiattisak Hongku, Suteekhanit Hahtapornsawan, Khamin Chinsakchai, Chumpol Wongwanit, Nuttawut Sermsathanasawadi
Summary: The aim of this study was to validate the Critical Limb Ischemia Frailty Index (CLIFI) as a predictor of 2-year amputation-free survival after infrapopliteal endovascular treatment for chronic limb-threatening ischemia (CLTI) in Thai patients. The results showed that the Geriatric Nutritional Risk Index (GNRI) was an independent risk factor for amputation within two years after revascularization, but the CLIFI did not significantly predict 2-year amputation in this patient population.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Surgery
Jorge A. Miranda, Zachary Pallister, Sherene Sharath, Lucas Ferrer, Jayer Chung, Brian Lepow, Joseph L. Mills, Miguel Montero-Baker
Summary: This study reviewed the outcomes of venous arterialization (VA) in chronic limb-threatening ischemia (CLTI). The findings suggest that superficial and deep VA are feasible options for limb salvage in patients who cannot undergo conventional revascularization methods.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Medicine, General & Internal
Alessia Scatena, Pasquale Petruzzi, Filippo Maioli, Francesca Lucaroni, Cristina Ambrosone, Giorgio Ventoruzzo, Francesco Liistro, Danilo Tacconi, Marianna Di Filippi, Nico Attempati, Leonardo Palombi, Leonardo Ercolini, Leonardo Bolognese
Summary: The study showed that treatment with autologous PBMNC implants in NO-CLI patients with DFUs significantly reduced amputation rate, improved survival, and promoted wound healing. Autologous PBMNC injection may effectively prevent amputations in patients with DFUs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Waseem Wahood, Sue Duval, Edwin A. Takahashi, Eric A. Secemsky, Sanjay Misra
Summary: This study analyzes the disparities in the treatment of critical limb ischemia (CLI) among different races over a 14-year period. The findings indicate that non-White patients are more likely to receive invasive treatments, including major amputations and revascularization, compared with White patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Keren Lehavot, Jessica P. Young, Rachel M. Thomas, Rhonda M. Williams, Aaron P. Turner, Daniel C. Norvell, Joseph M. Czerniecki, Anna Korpak, Alyson J. Littman
Summary: This study aims to describe the experiences of women Veterans with lower extremity amputation (LEA) related to prosthetic care provision and devices. The findings revealed that women Veterans with LEA have a high demand for individualized assessment and a tailored prosthetic limb prescription process. They also expressed the desire for prosthetists who listen to and understand their needs.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Linda J. Resnik, Mathew L. Borgia, Melissa A. Clark, Emily Graczyk, Jacob Segil, Pengsheng Ni
Summary: This study validated the Patient Experience Measure (PEM) for assessing psychosocial outcomes of sensory-enabled upper limb prostheses. Through a sample of 677 individuals, a six-scale model was identified through exploratory and confirmatory factor analysis, showing good fit and reliability. The PEM provides a reliable and valid tool for measuring the psychosocial impact of advanced prosthetic technologies.
Article
Peripheral Vascular Disease
Margaret Nalugo, Nikolai Harroun, Chenglong Li, Larisa Belaygorod, Clay F. Semenkovich, Mohamed A. Zayed
Summary: A reported increased incidence of lower extremity amputations in individuals with diabetes treated with canagliflozin raises concerns about the drug's potential impact on peripheral tissue recovery following ischemic events. Canagliflozin appears to impede tissue recovery and may affect peripheral limb perfusion, indicating the need for further clinical investigation in diabetic individuals with a history of peripheral artery disease.
Article
Surgery
Eva Torbjornsson, Ann-Mari Fagerdahl, Lena Blomgren, Lennart Bostrom, Carin Ottosson, Jonas Malmstedt
Summary: The study revealed that patients with CLTI undergoing amputation with ischemic pain as an indication have a significantly higher risk of reamputation, while older age is associated with an increased risk of mortality.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Medicine, General & Internal
Sorin Barac, Roxana Ramona Onofrei, Petru Vlad Neagoe, Alexandra Ioana Popescu, Stelian Pantea, Andreea Luciana Rata
Summary: In an observational study on patients with acute limb ischemia and SARS-CoV-2 infection, it was found that the presence of SARS-CoV-2 did not influence amputation-free survival rate, but was associated with arterial thrombosis and acute ischemic events. The standard treatment of open surgery or endovascular revascularization in these patients is crucial for lower limb salvage.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Zane B. Perkins, Alexander J. Kersey, Joseph M. White, Alexis L. Lauria, Brandon W. Propper, Nigel R. M. Tai, Todd E. Rasmussen
Summary: The study found that successful limb salvage is closely related to the duration of ischemia, with a 10% reduction in the probability of successful limb salvage for every hour delay to revascularization. Military trauma systems should prioritize rapid hemorrhage control and early limb revascularization.
Article
Peripheral Vascular Disease
Jeremy B. Provance, John A. Spertus, Philip G. Jones, Mark A. Hoffman, Matthew C. Bunte, Todd R. Vogel, Carlos Mena-Hurtado, Kim G. Smolderen
Summary: This study used an EHR database to investigate the 30-day major amputation rates following PVI in patients with CLI. The results showed that amputation rates varied across institutions, and patient-level factors and site characteristics accounted for most of the variation in these rates.
Review
Medicine, General & Internal
Madhan Jeyaraman, Somumurthy Nagarajan, Nicola Maffulli, R. P. Packkyarathinam, Naveen Jeyaraman, N. Arulkumar, Manish Khanna, Sankalp Yadav, Ashim Gupta
Summary: Critical limb ischemia (CLI) is a serious consequence of peripheral artery disease, leading to significant morbidity and economic burden. Current treatment modalities are unsatisfactory, and stem cell therapy (SCT) offers promising results by promoting angiogenesis and improving blood supply to the ischemic limb.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Surgery
Jesse A. Columbo, Ravinder Kang, Emily L. Spangler, Karina Newhall, Benjamin S. Brooke, Hasan Dosluoglu, Eugene S. Lee, Joseph D. Raffetto, Peter K. Henke, Gale S. Tang, Leila Mureebe, Panagoitis Kougias, Jason Johanning, Shipra Arya, Salvatore T. Scali, David H. Stone, Bjoern D. Suckow, Kristine Orion, Vivienne Halpern, Jessica O'Connell, Daniel Inhat, Peter Nelson, Edith Tzeng, Wei Zhou, Michael Barry, Brenda Sirovich, Philip P. Goodney
ANNALS OF VASCULAR SURGERY
(2020)
Article
Surgery
Jesse A. Columbo, Pablo Martinez-Camblor, Alistair James O'Malley, Bjoern D. Suckow, Andrew W. Hoel, David H. Stone, Andres Schanzer, Marc L. Schermerhorn, Art Sedrakyan, Philip P. Goodney
Summary: For patients undergoing endovascular abdominal aortic aneurysm repair, the likelihood of reintervention is high, but clinical factors at the time of repair can predict those at highest risk.
Article
Surgery
Peter B. Anderson, Zachary J. Wanken, Jennifer L. Perri, Jesse A. Columbo, Ravinder Kang, Emily L. Spangler, Karina Newhall, Benjamin S. Brooke, Hasan Dosluoglu, Eugene S. Lee, Joseph D. Raffetto, Peter K. Henke, Gale L. Tang, Leila Mureebe, Panagiotis Kougias, Jason Johanning, Shipra Arya, Salvatore T. Scali, David H. Stone, Bjoern D. Suckow, Kristine Orion, Vivienne Halpern, Jessica O'Connell, Daniel Inhat, Peter Nelson, Edith Tzeng, Wei Zhou, Michael Barry, Brenda Sirovich, Philip P. Goodney
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Surgery
Victoria Teveris, Jesse Columbo, Peter Bartline, Philip Goodney, David Stone, Bjoern Suckow
ANNALS OF VASCULAR SURGERY
(2020)
Article
Surgery
Spencer W. Trooboff, Zachary J. Wanken, Barbara Gladders, Brian P. Lucas, Kayla O. Moore, J. Aaron Barnes, Art Sedrakyan, Jesse A. Columbo, Bjoern D. Suckow, David H. Stone, Philip P. Goodney
ANNALS OF VASCULAR SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Jesse A. Columbo, Robert M. Zwolak, Edward J. Arous, Philip P. Goodney, Michael P. Lilly, H. Gilbert Welch
Article
Surgery
Dean J. Arnaoutakis, Salvatore T. Scali, Dan Neal, Kristina A. Giles, Thomas S. Huber, Richard J. Powell, Philip P. Goodney, Bjoern D. Suckow, Jeanwan Kang, Jesse A. Columbo, David H. Stone
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Surgery
Zachary J. Wanken, Peter B. Anderson, Sarah Y. Bessen, John B. Rode, Jesse A. Columbo, Spencer W. Trooboff, Kayla O. Moore, Philip P. Goodney
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Surgery
J. Aaron Barnes, Jesse A. Columbo, Aravind S. Ponukumati, Robert M. Zwolak, Frederick T. Olive, Philip P. Goodney, Richard J. Powell, Nikolaos Zacharias
ANNALS OF VASCULAR SURGERY
(2020)
Letter
Cardiac & Cardiovascular Systems
Zachary J. Wanken, Spencer W. Trooboff, Barbara Gladders, Jesse A. Columbo, Niveditta Ramkumar, Andrea M. Austin, David H. Stone, Matthew W. Mell, Art Sedrakyan, Philip P. Goodney
Article
Cardiac & Cardiovascular Systems
Spencer W. Trooboff, Zachary J. Wanken, Barbara Gladders, Jesse A. Columbo, Jon D. Lurie, Philip P. Goodney
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2020)
Review
Surgery
Zachary J. Wanken, J. Aaron Barnes, Spencer W. Trooboff, Jesse A. Columbo, Tarun K. Jella, Daniel J. Kim, Arian Khoshgowari, Natalie B. V. Riblet, Philip P. Goodney
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Surgery
Jesse A. Columbo, J. Aaron Barnes, Douglas W. Jones, Bjoern D. Suckow, Daniel B. Walsh, Richard J. Powell, Philip P. Goodney, David H. Stone
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Surgery
Nikolaos Zacharias, Philip P. Goodney, Joseph P. DeSimone, David H. Stone, Zachary J. Wanken, Bjoern D. Suckow, Jesse A. Columbo, Richard J. Powell
ANNALS OF VASCULAR SURGERY
(2020)
Article
Surgery
J. Aaron Barnes, Jesse A. Columbo, David P. Kuwayama
JOURNAL OF VASCULAR SURGERY CASES AND INNOVATIVE TECHNIQUES
(2020)