Collagen analysis by second-harmonic generation microscopy predicts outcome of luminal breast cancer

Using second harmonic generation to predict patient outcome in solid tumors

(2015) K. Burke et al.   BMC CANCER

The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer

(2015) F J A Gujam et al.   BRITISH JOURNAL OF CANCER

Second-harmonic generation scattering directionality predicts tumor cell motility in collagen gels

(2015) Kathleen A. Burke et al.   JOURNAL OF BIOMEDICAL OPTICS

Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts

(2015) Alex J. Walsh et al.   JOURNAL OF BIOMEDICAL OPTICS

Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial

(2015) T.J.A. Dekker et al.   Molecular Oncology

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

A Novel Morphologic-Molecular Recurrence Predictive Model Refines Traditional Prognostic Tools for Invasive Breast Carcinoma

(2014) Yun-Bi Ni et al.   ANNALS OF SURGICAL ONCOLOGY

Alterations in collagen fibre patterns in breast cancer. A premise for tumour invasiveness?

(2014) Anders Brabrand et al.   APMIS

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment

(2014) D. Herrmann et al.   CARCINOGENESIS

FibrilTool, an ImageJ plug-in to quantify fibrillar structures in raw microscopy images

(2014) Arezki Boudaoud et al.   Nature Protocols

CCAST: A Model-Based Gating Strategy to Isolate Homogeneous Subpopulations in a Heterogeneous Population of Single Cells

(2014) Benedict Anchang et al.   PLoS Computational Biology

Fibrotic Focus in Breast Carcinomas: Relationship with Prognostic Parameters and Biomarkers

(2013) S. Shafaq Mujtaba et al.   ANNALS OF SURGICAL ONCOLOGY

Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

(2013) Jérôme Galon et al.   JOURNAL OF PATHOLOGY

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Luminal breast cancer: from biology to treatment

(2013) Michail Ignatiadis et al.   Nature Reviews Clinical Oncology

The Genomic Landscape of Breast Cancer as a Therapeutic Roadmap

(2013) Matthew J. Ellis et al.   Cancer Discovery

Collagen I fiber density increases in lymph node positive breast cancers: pilot study

(2012) Samata M. Kakkad et al.   JOURNAL OF BIOMEDICAL OPTICS

Second harmonic generation reveals matrix alterations during breast tumor progression

(2012) Kathleen Burke et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative assessment of forward and backward second harmonic three dimensional images of collagen Type I matrix remodeling in a stimulated cellular environment

(2012) Thomas Abraham et al.   JOURNAL OF STRUCTURAL BIOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

(2012) Xiyi Chen et al.   Nature Protocols

Optical Biomarkers of Serous and Mucinous Human Ovarian Tumor Assessed with Nonlinear Optics Microscopies

(2012) Javier Adur et al.   PLoS One

Quantifying collagen structure in breast biopsies using second-harmonic generation imaging

(2012) Raghu Ambekar et al.   Biomedical Optics Express

Expression of cyclooxygenase-2 (COX-2) and p53 in neighboring invasive and in situ components of breast tumors

(2011) Katia Piton Serra et al.   ACTA HISTOCHEMICA

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Second Harmonic Generation Imaging Microscopy: Applications to Diseases Diagnostics

(2011) Paul Campagnola   ANALYTICAL CHEMISTRY

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

(2011) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

(2011) R. Rezakhaniha et al.   Biomechanics and Modeling in Mechanobiology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Current and emerging biomarkers in breast cancer: prognosis and prediction

(2010) Marion T Weigel et al.   ENDOCRINE-RELATED CANCER

Breast Cancer Subtypes and the Risk of Local and Regional Relapse

(2010) K. David Voduc et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor stroma derived biomarkers in cancer

(2009) Malin Sund et al.   CANCER AND METASTASIS REVIEWS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Single-wavelength reflected confocal and multiphoton microscopy for tissue imaging

(2009) Wei-Liang Chen et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative discrimination between endogenous SHG sources in mammalian tissue, based on their polarization response

(2009) Sotiris Psilodimitrakopoulos et al.   OPTICS EXPRESS

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Cartilaginous features in matrix-producing carcinoma of the breast: four cases report with histochemical and immunohistochemical analysis of matrix molecules

(2008) Kimihide Kusafuka et al.   MODERN PATHOLOGY

Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma

(2008) Xiaoxing Han et al.   OPTICS EXPRESS