Article
Clinical Neurology
Nawaraj Bhattarai, Christopher Price, Peter McMeekin, Mehdi Javanbakht, Luke Vale, Gary A. Ford, Lisa Shaw
Summary: The PASTA pathway may be considered cost-effective, especially in areas where stroke specialist availability is limited, as the trial results showed lower costs and more dominant cost-effectiveness in the PASTA group.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Article
Medicine, Research & Experimental
Lili Song, Xin Hu, Lu Ma, Xiaoying Chen, Menglu Ouyang, Laurent Billot, Qiang Li, Paula Munoz-Venturelli, Carlos Abanto, Octavio Marques Pontes-Neto, Arauz Antonio, Mohammad Wasay, Asita de Silva, Nguyen Huy Thang, Jeyaraj Durai Pandian, Kolawole Wasiu Wahab, Chao You, Craig S. Anderson
Summary: INTERACT3 is a pragmatic, international, multicenter, stepped-wedge cluster-randomized controlled trial aiming to determine the effectiveness of a multifaceted care package in adult patients with acute intracerebral hemorrhage.
Article
Biochemistry & Molecular Biology
Jozine M. ter Maaten, Iris E. Beldhuis, Peter van der Meer, Jan A. Krikken, Douwe Postmus, Jenifer E. Coster, Wybe Nieuwland, Dirk J. van Veldhuisen, Adriaan A. Voors, Kevin Damman
Summary: Measurement of natriuresis has been suggested as a first step towards personalized treatment of acute heart failure, but there were no significant differences in all-cause mortality or heart failure rehospitalization compared to standard of care.
Article
Geriatrics & Gerontology
Maureen Markle-Reid, Kathryn Fisher, Kimberly M. Walker, Marla Beauchamp, Jill I. Cameron, David Dayler, Rebecca Fleck, Amiram Gafni, Rebecca Ganann, Ken Hajas, Barbara Koetsier, Robert Mahony, Chris Pollard, Jim Prescott, Tammy Rooke, Carly Whitmore
Summary: This study aimed to test the effectiveness of a Transitional Care Stroke Intervention (TCSI) compared to usual care in older adults with stroke and multimorbidity. The results showed that the TCSI did not significantly reduce the risk of hospital readmission, but it improved physical functioning, stroke self-management, and patient experience without increasing healthcare costs. The challenges caused by the COVID-19 pandemic and the shift to virtual delivery may have influenced the results. A larger study is needed to determine the effectiveness and scalability of the intervention in different geographic settings and populations.
Article
Medicine, General & Internal
Bobby G. Warren, Aaron Barrett, Amanda Graves, Carly King, Nicholas A. Turner, Deverick J. Anderson
Summary: This study compared the efficacy of an enhanced daily disinfection strategy with standard disinfection in acute care hospital rooms. The results showed that the enhanced strategy reduced environmental bioburden and decreased contamination with patient-associated clinically important pathogens.
Article
Health Care Sciences & Services
Yiyi Cai, Claire Shuiqing Zhang, Anthony Lin Zhang, Cliff Da Costa, Charlie Changli Xue, Zehuai Wen
Summary: This preliminary study on electroacupuncture for poststroke spasticity found no significant difference in outcomes between the intervention group and control group in terms of MAS, Fugl-Meyer Assessment, or Barthel Index. Longer treatment and follow-up periods are recommended for future full-scale trials to evaluate the effectiveness and safety of EA more accurately.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Cardiac & Cardiovascular Systems
Valerie Santschi, Gregoire Wuerzner, Bruno Pais, Arnaud Chiolero, Philippe Schaller, Lyne Cloutier, Gilles Paradis, Michel Burnier
Summary: The interprofessional team-based care (TBC) intervention can help decrease long-term systolic blood pressure among uncontrolled hypertensive patients, although there was no significant effect on blood pressure at 6 months of follow-up. At 12 months, the TBC group tended to have better control in systolic blood pressure but not in diastolic blood pressure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Critical Care Medicine
Peerapat Thanapongsatorn, Kamolthip Chaikomon, Nuttha Lumlertgul, Khanitha Yimsangyad, Akarathep Leewongworasingh, Win Kulvichit, Phatadon Sirivongrangson, Sadudee Peerapornratana, Weerachai Chaijamorn, Yingyos Avihingsanon, Nattachai Srisawat
Summary: The study showed that implementing comprehensive care by an MDCT can improve outcomes for severe AKI survivors, including better feasibility outcomes such as dietary records, drug reconciliation, and drug alerts, as well as reduced urine albumin levels and improved blood pressure control.
Article
Clinical Neurology
Laurent Billot, Lili Song, Xin Hu, Lu Ma, Menglu Ouyang, Xiaoying Chen, Chao You, Craig S. Anderson
Summary: The INTEnsive care bundle with blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT3) is an international study comparing the effectiveness of a goal-directed care bundle in patients with acute intracerebral hemorrhage. The study involves 110 hospitals in low- and middle-income countries and will be conducted from 2017 to 2022 using a stepped-wedge design. The results will be analyzed using statistical methods.
CEREBROVASCULAR DISEASES
(2023)
Article
Critical Care Medicine
Garrett Rampon, Shijing Jia, Ritwick Agrawal, Nicholas Arnold, Alejandro Martin-Quiros, Ernest A. Fischer, James Malatack, Nikhil Jagan, Amen Sergew, Amy Hajari Case, Kristin Miller, Maged Tanios, Gheorghe Doros, Craig S. Ross, Michael A. Garcia, Kari R. Gillmeyer, Nicholas G. Griffiths, Badr Jandali, Katherine L. Modzelewski, Justin M. Rucci, Steven Q. Simpson, Allan J. Walkey, Nicholas A. Bosch
Summary: This study aimed to investigate the effectiveness of smartphone-guided self-prone positioning therapy in nonintubated patients with COVID-19. The results showed that this intervention did not promote strong adherence to prone positioning among the patients.
Article
Urology & Nephrology
Dale E. Lupu, Annette Aldous, Elizabeth Anderson, Jane O. Schell, Hunter Groninger, Michael J. Sherman, Joseph R. Aiello, Samuel J. Simmens
Summary: This study examined the impact of coaching in CKD clinics on patient engagement with advance care planning (ACP). The results showed that coached patients had higher scores on the ACP engagement scale and were more likely to have a documented advance directive or portable medical order. However, the effect of coaching may be influenced by the healthcare environment in which it is delivered.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Medicine, General & Internal
Teresa A. Hillier, Kathryn L. Pedula, Keith K. Ogasawara, Kimberly K. Vesco, Caryn E. S. Oshiro, Suzanne L. Lubarsky, Jan Van Marter
Summary: In this study comparing one-step screening with two-step screening for gestational diabetes mellitus, the one-step approach resulted in more diagnoses of gestational diabetes mellitus but did not have a significant impact on the incidence of adverse perinatal and maternal outcomes.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Rehabilitation
Barbara J. Lutz, Anna M. Kucharska-Newton, Sara B. Jones, Matthew A. Psioda, Sabina B. Gesell, Sylvia W. Coleman, Anna M. Johnson, Meghan D. Radman, Samantha Levy, Janet Prvu Bettger, Janet K. Freburger, Aileen Chou, Joan Celestino, Wayne D. Rosamond, Cheryl D. Bushnell, Pamela W. Duncan
Summary: This study investigated the caregiver strain among caregivers of stroke patients at home and found that female caregivers reported higher levels of strain. Despite providing significant amount of care over a long duration, overall caregiver strain was relatively low.
TOPICS IN STROKE REHABILITATION
(2023)
Article
Clinical Neurology
Won Kee Chang, Won-Seok Kim, Min Kyun Sohn, Sungju Jee, Yong-Il Shin, Sung-Hwa Ko, Minsu Ock, Hyun Joo Kim, Nam-Jong Paik
Summary: This study aims to examine the feasibility of Early Supported Discharge (ESD) in Korea through a multicenter randomized controlled trial involving 90 post-acute stroke patients. The ESD group will receive personalized discharge planning and home-based rehabilitation, while the CR group will follow hospital policies for rehabilitation practices. The study will contribute evidence on the applicability of ESD in Korea, with outcomes measured at various time points up to 3 months post-onset.
FRONTIERS IN NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Aaron J. Chau, Rebecca L. Sudore, Ron D. Hays, Chi-Hong Tseng, Anne M. Walling, Maryam Rahimi, Lisa Gibbs, Kanan Patel, Fernando Javier Sanz Vidorreta, Neil S. Wenger
Summary: This study aimed to assess the effect of phone outreach, in addition to standard mail survey recruitment, in a population-based ACP pragmatic trial at three academic health systems in California. The results showed that phone outreach significantly enhanced the recruitment of underrepresented seriously ill patients, which is important for addressing the issue of representativeness in research.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Rehabilitation
Janet K. Freburger, Dongmei Li, Anna M. Johnson, Erin P. Fraher
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2018)
Article
Health Care Sciences & Services
Sabina B. Gesell, Cheryl D. Bushnell, Sara B. Jones, Sylvia W. Coleman, Samantha M. Levy, James G. Xenakis, Barbara J. Lutz, Janet Prvu Bettger, Janet Freburger, Jacqueline R. Halladay, Anna M. Johnson, Anna M. Kucharska-Newton, Laurie H. Mettam, Amy M. Pastva, Matthew A. Psioda, Meghan D. Radman, Wayne D. Rosamond, Mysha E. Sissine, Joanne Halls, Pamela W. Duncan
BMC HEALTH SERVICES RESEARCH
(2019)
Article
Cardiac & Cardiovascular Systems
Pamela W. Duncan, Cheryl D. Bushnell, Sara B. Jones, Matthew A. Psioda, Sabina B. Gesell, Ralph B. D'Agostino, Mysha E. Sissine, Sylvia W. Coleman, Anna M. Johnson, Blair F. Barton-Percival, Janet Prvu-Bettger, Adrienne G. Calhoun, Doyle M. Cummings, Janet K. Freburger, Jacqueline R. Halladay, Anna M. Kucharska-Newton, Gladys Lundy-Lamm, Barbara J. Lutz, Laurie H. Mettam, Amy M. Pastva, James G. Xenakis, Walter T. Ambrosius, Meghan D. Radman, Betsy Vetter, Wayne D. Rosamond
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2020)
Article
Rehabilitation
Amy M. Pastva, Peter C. Coyle, Sylvia W. Coleman, Meghan D. Radman, Karen M. Taylor, Sara B. Jones, Cheryl D. Bushnell, Wayne D. Rosamond, Anna M. Johnson, Pamela W. Duncan, Janet K. Freburger
Summary: The Movement Matters Activity Program for Stroke (MMAP) is designed to maximize survivor health, recovery, and functional independence in the community and to promote evidence-based rehabilitative care. Implementation of MMAP faced challenges and was influenced by provider- and system-level factors. Successful implementation appeared to be related to empowered MMAP champions in vertically integrated systems that embraced innovation.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Letter
Medicine, General & Internal
Wayne D. Rosamond, Anna M. Johnson, Jessica K. Zegre-Hemsey
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Article
Critical Care Medicine
Jessica K. Zegre-Hemsey, Mary E. Grewe, Anna M. Johnson, Evan Arnold, Christopher J. Cunningham, Brittany M. Bogle, Wayne D. Rosamond
Article
Clinical Neurology
Pamela W. Duncan, Cheryl Bushnell, Mysha Sissine, Sylvia Coleman, Barbara J. Lutz, Anna M. Johnson, Meghan Radman, Janet Pvru Bettger, Richard D. Zorowitz, Joel Stein
Summary: Despite advancements in acute care therapies for stroke, there are still gaps and challenges in postacute stroke care. Global attention needs to be focused on improving postacute care and outcomes for stroke survivors to enhance recovery and secondary prevention efforts.
Letter
Emergency Medicine
Wayne D. Rosamond, Anna M. Kucharska-Newton, Sara B. Jones, Matthew A. Psioda, Barbara J. Lutz, Anna M. Johnson, Sylvia W. Coleman, Samantha R. Schilsky, Mehul D. Patel, Pamela W. Duncan
ACADEMIC EMERGENCY MEDICINE
(2022)
Article
Rehabilitation
Janet K. Freburger, Amy M. Pastva, Sylvia W. Coleman, Kennedy M. Peter, Anna M. Kucharska-Newton, Anna M. Johnson, Matthew A. Psioda, Pamela W. Duncan, Cheryl D. Bushnell, Wayne D. Rosamond, Sara B. Jones
Summary: The study aims to examine the impact of a comprehensive transitional care model on the utilization of skilled nursing facility (SNF) and inpatient rehabilitation facility (IRF) care for stroke patients in the 12 months following discharge home, as well as identify predictors for SNF or IRF admission after discharge home.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Cardiac & Cardiovascular Systems
Cheryl D. Bushnell, Anna M. Kucharska-Newton, Sara B. Jones, Matthew A. Psioda, Anna M. Johnson, Laurie C. Daras, Jacqueline R. Halladay, Janet Prvu Bettger, Janet K. Freburger, Sabina B. Gesell, Sylvia W. Coleman, Mysha E. Sissine, Fang Wen, Gary P. Hunt, Wayne D. Rosamond, Pamela W. Duncan
Summary: In a pragmatic trial of patients with complex minor stroke/transient ischemic attack discharged from 40 diverse hospitals, there was no difference in the risk of readmission or mortality with COMPASS-TC compared to usual care. The study could not conclusively determine the reason for the lack of effectiveness of the intervention.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Emergency Medicine
Anna Johnson, Christopher Cunningham, Evan Arnold, Wayne Rosamond, Jessica Zegre-Hemsey
Summary: The use of drones in emergency medicine has been expanding rapidly in recent years due to advancements in technology and decreasing costs. Current applications include delivering medical supplies such as defibrillators and blood products, as well as aiding in search and rescue operations and disaster response. Challenges to their widespread use in emergency medicine include regulatory issues, safety concerns, and privacy considerations, but research suggests that drones are feasible, cost-effective, and will be widely accepted.
OPEN ACCESS EMERGENCY MEDICINE
(2021)
Article
Rehabilitation
Barbara J. Lutz, Anna M. Kucharska-Newton, Sara B. Jones, Matthew A. Psioda, Sabina B. Gesell, Sylvia W. Coleman, Anna M. Johnson, Meghan D. Radman, Samantha Levy, Janet Prvu Bettger, Janet K. Freburger, Aileen Chou, Joan Celestino, Wayne D. Rosamond, Cheryl D. Bushnell, Pamela W. Duncan
Summary: This study investigated the caregiver strain among caregivers of stroke patients at home and found that female caregivers reported higher levels of strain. Despite providing significant amount of care over a long duration, overall caregiver strain was relatively low.
TOPICS IN STROKE REHABILITATION
(2023)
Article
Medicine, Research & Experimental
Sabina B. Gesell, Sylvia W. Coleman, Laurie H. Mettam, Anna M. Johnson, Mysha E. Sissine, Pamela W. Duncan
Summary: This qualitative study investigated how stakeholders contributed to a multisite pragmatic clinical trial, resulting in changes to study design and protocol. Stakeholder input influenced aspects such as the care model, provider training, and support for caregivers and community-based service providers. The involvement of stakeholders added value to both research and health service delivery, warranting further studies to test the impact of stakeholder-informed elements of study implementation.
JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE
(2021)
Article
Gerontology
Barbara J. Lutz, Alexandria E. Reimold, Sylvia W. Coleman, Amy K. Guzik, Laurie P. Russell, Meghan D. Radman, Anna M. Johnson, Pamela W. Duncan, Cheryl D. Bushnell, Wayne D. Rosamond, Sabina B. Gesell
Article
Medicine, Research & Experimental
Sabina B. Gesell, Jacqueline R. Halladay, Laurie H. Mettam, Mysha E. Sissine, B. Lynette Staplefoote-Boynton, Pamela W. Duncan
JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE
(2020)