Journal
TRENDS IN NEUROSCIENCES
Volume 41, Issue 6, Pages 325-327Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tins.2018.03.013
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Funding
- National Institute of Neurological Disorders and Stroke, National Institutes of Health (NIH) [R01NS091070]
- National Institute of General Medical Sciences (NIGMS), NIH [R01GM098931]
- Kavli Institute for Neuroscience
- NIGMS, NIH [5T32GM100884]
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Today, we understand peptide transmitters to be signaling molecules that modulate neural activity. However, in 1982 little was known about neuropeptides and their role in neural communication. The influential 1982 paper by Jan and Jan reported definitive evidence that a presynaptically released neuropeptide evokes postsynaptic responses in an identified cholinergic synapse, thereby fueling a new era in neuroscience.
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