Journal
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume 29, Issue 5, Pages 283-284Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2018.02.011
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In Cell Reports, Christoffersen et al. [1] demonstrate that sphingosine 1-phosphate (S1P) bound to apolipoprotein M (apoM) regulates the activity and mass of brown adipose tissue (BAT). They found mice lacking apoM to have hyperactive BAT with high triglyceride (TG) utilization, resulting in low white adipose tissue (WAT) mass and low body weight.
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