Article
Medicine, Research & Experimental
Dongliang Zhang, Ying Wang, Lei Liu, Zeng Li, Shengke Yang, Weixin Zhao, Xiang Wang, Hong Liao, Shukui Zhou
Summary: This study established prostate cancer models using cell sheet technology and compared their efficiency of tumor formation with cell suspension injection. The results showed that the orthotopic tumor formation rate in the cell sheet injection group was significantly better than that in the cell suspension injection group. Furthermore, the tumors in the cell sheet injection group had a higher density of micro-vessels, more collagen deposition, and a lower apoptotic rate. Cell sheet technology has potential applications in preclinical drug development, drug resistance mechanisms, and individualized therapy for prostate cancer.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Raymond Lam, Steven Naoum, Paul Abbott, Mithran S. Goonewardene
Summary: This study assessed pulp blood flow and pulp sensibility changes in healthy and traumatized teeth undergoing maxillary expansion. The results suggest that patients with transverse discrepancies and a history of trauma may benefit from MARME, as MARME had less impact on PBF compared to RME.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Alfredo Franco Queiroz, Mirian Marubayashi Hidalgo, Alberto Consolaro, Sonia Regina Panzarini, Alline Batistussi Franca, Moriel Evangelista Melo, Wilson Roberto Poi
Summary: The use of systemic antibiotic therapy with amoxicillin or tetracycline for 7 days did not contribute to pulp repair following extrusive luxation or avulsion in rats. However, amoxicillin may have some effects when used for a longer period of time in cases of avulsion.
DENTAL TRAUMATOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Wei Duan, Yufei Chen, Qi Zhang, Xiang Lin, Xiaoyu Yang
Summary: This study proposed a two-phase deep learning solution for accurately extracting and segmenting single teeth and pulp cavities, achieving high accuracy in experimental results.
DENTOMAXILLOFACIAL RADIOLOGY
(2021)
Article
Education, Scientific Disciplines
Wen Sun, Hongyu Chen, Yi Zhong, Wei Zhang, Fengqing Chu, Lin Li, Yue Chen, Xiang Wang, Qirui Wang, Yuxin Wang, Yongyue Wei, Laikui Liu, Yan Xu
Summary: A study introduced an online dental learning platform with 3D tooth models based on micro-computed tomography, and found that the use of this platform had a positive impact on dental anatomy education according to a cohort study. Participants in the Digital group showed improved scores and positive attitudes towards the 3D models.
ANATOMICAL SCIENCES EDUCATION
(2022)
Article
Materials Science, Biomaterials
Mariano S. Pedano, Kumiko Yoshihara, Xin Li, Bernardo Camargo, Kirsten Van Landuyt, Bart Van Meerbeek
Summary: This study aimed to evaluate a series of innovative resin-modified calcium-silicate pulp-capping cements (Rm-CSCs) in terms of flexural strength, shear bond strength to dentin, pH, and calcium release. The results showed that the experimental Rm-CSCs performed well in flexural strength and bond strength to dentin, with one variant (Exp_HEAA) demonstrating superior calcium release and pH maintenance. Additionally, Exp_HEAA exhibited pulp-healing initiation in direct contact with human dental pulp tissue in the ex-vivo human vital tooth-culture model.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Surgery
Masahiro Iseki, Masamichi Mizuma, Shohei Wakao, Yoshihiro Kushida, Katsuyoshi Kudo, Masahiko Fukase, Masaharu Ishida, Tomoyuki Ono, Mitsuhiro Shimura, Ichiro Ise, Yukie Suzuki, Teruko Sueta, Ryuta Asada, Shinobu Shimizu, Yoshiyuki Ueno, Mari Dezawa, Michiaki Unno
Summary: The study demonstrates that allogeneic Muse cell administration via the portal vein can effectively improve liver dysfunction in a swine model of PHLF, with significant reparative effects.
Article
Medicine, General & Internal
Venkatalakshmi Aparna Potruli, BESHiA ARNolD, S. A. N. T. A. N. A. SENTHil KuMAR, SATHiSH KuMAR JEyAGopAl, P. A. V. A. N. A. BASkER
Summary: Pulp polyp is a reactive lesion that can occur as a result of chronic caries or dental trauma. It is commonly found in molars and rarely in anterior teeth. This case report presents an unusual presentation of pulp polyp in an 11-year-old girl, causing pain, discomfort, and bleeding on irritation. The unique worm-shaped appearance posed a diagnostic dilemma, but was confirmed through histological examination.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
M. Guivarc'h, C. Jeanneau, T. Giraud, L. Pommel, I About, A. A. Azim, Frederic Bukiet
CLINICAL ORAL INVESTIGATIONS
(2020)
Article
Dentistry, Oral Surgery & Medicine
Mariel Webber, Lucila Piasecki, Eduardo Inocente Jussiani, Avacir Casanova Andrello, Paulo Jose dos Reis, Katharina A. Azim, Adham A. Azim
JOURNAL OF ENDODONTICS
(2020)
Article
Dentistry, Oral Surgery & Medicine
Hacer Aksel, Steven Makowka, Fatima Bosaid, Mary Grace Guardian, Debanjan Sarkar, Adham A. Azim
Summary: The study found that heat application can alter the setting time and flow characteristics of root canal sealers; different sealers showed distinct chemical properties after heat application; HiFlow exhibited the best flow and lower viscosity at high temperatures, while BioRoot experienced weight loss and reduced flow characteristics.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
A. A. Azim, H. Albanyan, K. A. Azim, L. Piasecki
Summary: The success and survival rate of endodontic microsurgery was very high, and the occurrence of a major procedural error during surgery was the only factor affecting the outcome. GTR did not improve the outcome, but did affect the quality of apical bone remodelling following EMS.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Adham A. Azim, Howard H. Wang, Maksim Serebro
Summary: Endodontic microsurgery on the palatal root of maxillary molars can be challenging due to its proximity to the maxillary sinus floor and may require multiple surgical interventions, potentially leading to technical difficulties. Combining non-surgical retreatment and obturation of the palatal root with surgical intervention from the buccal side and sinus lift can effectively treat such conditions, as evidenced by healing and apical repositioning observed in follow-up cone-beam computed tomographic imaging.
JOURNAL OF ENDODONTICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Adham A. Azim, Theeb Alquria, Howard H. Wang, Lucila Piasecki
Summary: Management of patients with apical fenestration and clinical symptoms has traditionally involved apical root resection and placement within the bony crypt. However, in this case report, it was found that these traditional methods were not sufficient, leading to further bone loss and persistence of symptoms. A corrective surgery involving guided bone regeneration and decortication of the cortical plate was successful in resolving the patient's symptoms and increasing bone volume.
JOURNAL OF ENDODONTICS
(2021)
Letter
Dentistry, Oral Surgery & Medicine
Adham A. Azim
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Review
Cell & Tissue Engineering
Hacer Aksel, Xiaofei Zhu, Philippe Gauthier, Wenjing Zhang, Adham A. Azim, George T-J Huang
Summary: This review discusses the limitations of current management protocols for avulsed teeth, the application of cell-based therapy in periodontal ligament regeneration, the challenges of PDL regeneration on denuded roots, and the establishment of a new clinical protocol based on cell-based PDL regeneration studies.
STEM CELL RESEARCH & THERAPY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Ibrahim Alaugaily, Adham A. Azim
Summary: This study aimed to identify the clinical and radiographic characteristics of cracked teeth and teeth with vertical root fracture (VRF), and to find the association between the type of fracture and other features. Patterns of bone loss on CBCT imaging can differentiate between cracked teeth and teeth with VRF.
JOURNAL OF ENDODONTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Adham A. Azim, Khalid Merdad, Ove A. Peters
Summary: This survey aimed to determine the consensus among endodontic specialists and practitioners worldwide on the diagnosis of selected case scenarios, and to suggest modifications to the current diagnostic terms. The survey found a lack of consensus among clinicians, regardless of their training and region of practice, on the appropriate diagnostic terms for specific clinical conditions.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fatima Bosaid, Hacer Aksel, Adham A. Azim
Summary: All calcium silicate-based sealers showed similar antibacterial activity in neutral conditions, but BioRoot RCS demonstrated greater effectiveness in acidic conditions compared to EndoSequence BC and NeoMTA Plus. The pH values of the sealers ranged from 8.2 to 8.8 in neutral conditions, but decreased significantly in acidic conditions, with BioRoot RCS maintaining the highest pH. Acidic pH had a reducing effect on the antibacterial activity of the calcium silicate-based sealers.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Shehabeldin Saber, Shaimaa Abu El Sadat, Alya Taha, Nawar Naguib Nawar, Adham Abdel Azim
Summary: This study analysed the relationship between mandibular posterior teeth and surrounding anatomical structures using 170 CBCT images. The results showed that as teeth became more posterior, buccal bone thickness increased, lingual bone thickness decreased, and proximity to the mandibular canal became closer.
EUROPEAN ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sarah Alfadda, Theeb Alquria, Eda Karaismailoglu, Hacer Aksel, Adham A. Azim
Summary: The study showed that calcium hypochlorite (Ca[OCl](2)) had the best disinfection effect on root canals, but it also reduced cell viability and mineralization activity. However, the adverse effects on cells could be neutralized with 10% ascorbic acid.
JOURNAL OF ENDODONTICS
(2021)
Review
Dentistry, Oral Surgery & Medicine
Juzer Shabbir, Tazeen Zehra, Naheed Najmi, Arshad Hasan, Madiha Naz, Lucila Piasecki, Adham A. Azim
Summary: The majority of studies reviewed did not show clear benefits of minimally invasive access cavity designs, and some raised concerns about disinfection, filling, and restoring teeth with this approach. Therefore, there may be more risks than benefits associated with using minimally invasive access cavity designs for endodontic treatment, and clinicians should carefully consider when to apply this method.
JOURNAL OF ENDODONTICS
(2021)