Article
Cell & Tissue Engineering
Sungjun Kim, Yunyoung Choi, Wonjeong Lee, Kyobum Kim
Summary: This study developed interpenetrating network hydrogels using thiolated gelatin and poly(ethylene glycol) diacrylate with radical initiators, and investigated their physico-chemical characteristics. The results showed that the polymer concentration significantly manipulated the hydrogel characteristics, and no toxicity was observed on fibroblast and HaCaT cells for all hydrogel formulations.
TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Bao Le-Vinh, Christian Steinbring, Nguyet-Minh Nguyen Le, Barbara Matuszczak, Andreas Bernkop-Schnurch
Summary: Chitosan and its derivatives with high cell adhesion properties were designed and tested for their suitability as scaffold materials in tissue engineering. The attachment of a thiol group to chitosan significantly improved cell adhesion, with higher modification levels leading to better results. The resulting chitosan-based cryogels showed promise for 3D cell culture and tissue engineering.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Engineering, Chemical
Cody O. Crosby, Brett Stern, Nikhith Kalkunte, Shahar Pedahzur, Shreya Ramesh, Janet Zoldan
Summary: This article proposes the development of interpenetrating polymer network (IPN) hydrogels as biomaterial scaffolds in tissue engineering, aiming to address the current challenges in clinical translation. The authors review recent advancements in improving the mechanical strength, substrate-scale stiffness, electrical conductivity, and degradation of IPN hydrogels and highlight their incorporation into state-of-the-art tissue engineering technologies. These materials have critical importance in engineering functional tissues for transplantation, disease modeling, and drug screening.
REVIEWS IN CHEMICAL ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Aleksandra Serafin, Mario Culebras, Maurice N. Collins
Summary: Tissue engineering is proposed as a potential solution to organ shortages. Various hydrogel formulations have been studied, including organic and biocompatible materials that mimic the native tissue. However, comparing studies is difficult due to differences in material concentrations and preparation methods. The current study aims to investigate popular biomaterials and their behaviors for targeted tissue engineering strategies.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Multidisciplinary
Simona Summonte, Giuseppe Francesco Racaniello, Angela Lopedota, Nunzio Denora, Andreas Bernkop-Schnuerch
Summary: Thiomers, such as thiolated hyaluronic acid and chitosan, are widely studied for their high reactivity in hydrogel synthesis. They exhibit in situ gelling properties and can undergo various click reactions, making them versatile materials for tissue engineering, regenerative medicine, and drug delivery.
JOURNAL OF CONTROLLED RELEASE
(2021)
Review
Materials Science, Multidisciplinary
Yuanfeng Li, Junjie Chi, Xing Dong, Anh-Tuan Le, Keqing Shi, Yong Liu, Jian Xiao
Summary: G-quadruplex hydrogel is a self-assembled supramolecular hydrogel formed by guanine derivatives, which shows wide biomedical applications such as drug delivery, tissue engineering, and biosensing. Its advantages include biocompatibility, tunable multifunctionality, and cost-effective fabrication process. This review focuses on the fabrication and characterization of G-quadruplex hydrogels, as well as their applications in the biomedical area, aiming to promote the development of this field.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Xu Xue, Yan Hu, Sicheng Wang, Xiao Chen, Yingying Jiang, Jiacan Su
Summary: Bone tissue engineering provides promising tools for the treatment of bone-related diseases using biomimetic hydrogels. This article discusses the fabrication of biomimetic hydrogels using thermal sensitive polymers, mineral ions, chemically triggered agents, photo crosslinking initiators, and enzyme triggers. These hydrogels accelerate bone regeneration and the article also highlights key factors influencing therapeutic effects.
BIOACTIVE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Mengdi Xu, Luqin Hua, Lihao Gong, Jianlei Lu, Jinhui Wang, Chuanzhuang Zhao
Summary: The research demonstrates that tuning the interactions between polymer-polymer and polymer-AIEgen can activate aggregation-induced emission and design temperature- and pH-responsive hydrogels. These hydrogels not only record information but also function as luminescent soft actuators.
SCIENCE CHINA-CHEMISTRY
(2021)
Review
Engineering, Biomedical
Nikolas Di Caprio, Jason A. Burdick
Summary: Cellular spheroids are being explored as building blocks for tissue engineering and as tissue models. Biomaterials are being used to guide spheroid formation and function, and also facilitate the fabrication of tissue constructs. This review provides an overview of recent studies on the role of engineered biomaterials in supporting spheroids in biomedical applications.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Chemical
Vukasin Ugrinovic, Vesna Panic, Pavle Spasojevic, Sanja Seslija, Bojan Bozic, Rada Petrovic, Djordje Janackovic, Djordje Veljovic
Summary: This paper reports on the synthesis of PMAA/gelatin IPN hydrogels with adjustable properties through free-radical polymerization; it investigates the influence of different components in the precursor solution on the hydrogels' properties. The hydrogels exhibit pH sensitivity and promote cell proliferation.
POLYMER ENGINEERING AND SCIENCE
(2022)
Article
Chemistry, Applied
L. Barbier, M. Protat, P. Pipart, A. Marcellan, Y. Tran, D. Hourdet
Summary: Thermoassociating copolymers based on temperature-responsive poly(N-isopropylacrylamide-stat-N-tert-butylacrylamide) grafted onto hyaluronan were synthesized. By adjusting the composition of LCST side chains, an abrupt and reversible sol/gel transition of entangled solutions could be accurately controlled in the range of 10 to 35 degrees C. The thermoassociative behavior of these copolymers, which can form sticky gels at body temperature, shows great potential for biomedical applications such as injectable gels for drug delivery or tissue engineering.
CARBOHYDRATE POLYMERS
(2023)
Article
Biotechnology & Applied Microbiology
Keisuke Fukada, Koji Tachibana, Yuta Kurashina, Yosuke Kaneko, Tatsuaki Matsumoto, Takeshi Miyamoto, Yasuo Niki, Masaya Nakamura, Hiroaki Onoe
Summary: This paper presents a scalable microfiber-shaped tissue for macroscale tendon tissue reconstruction in vitro. The microfiber-shaped tendon-like tissues maintained their morphology and showed proper expression of tenomodulin and actin filaments. A macro-scale tendon tissue assembly was successfully constructed by bundling the microfiber-shaped tendon-like tissues, allowing for uniform cell distribution.
BIOTECHNOLOGY AND BIOENGINEERING
(2022)
Review
Engineering, Biomedical
Chaojie Yu, Fanglian Yao, Junjie Li
Summary: Recently, injectable conducting polymer-based hydrogels have gained attention in tissue engineering due to their controlled conductivity and minimally invasive procedures. Functional CPs play a crucial role in designing these hydrogels and have potential applications in neurological treatment, myocardial repair, and skeletal muscle regeneration.
ACTA BIOMATERIALIA
(2022)
Article
Biochemistry & Molecular Biology
Mohana Haghbin, Rahime Eshaghi Malekshah, Mahsa Sobhani, Zhila Izadi, Babak Haghshenas, Maryam Ghasemi, Behrooz Sadeghi Kalani, Hadi Samadian
Summary: The main purpose of this study is to synthesize and characterize a hydrogel composed of Persian gum and loaded with gentamicin (Gen)-loaded Clinoptilolite. The results showed that the fabricated hydrogel nanocomposite exhibits favorable physicochemical and biological properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Biomedical
Yunfan Zhang, Xueyu Dou, Lingyun Zhang, Hufei Wang, Ting Zhang, Rushui Bai, Qiannan Sun, Xing Wang, Tingting Yu, Decheng Wu, Bing Han, Xuliang Deng
Summary: In this study, a semi-interpenetrating network composite gel was prepared to fulfill the mechanical and cell compatibility requirements of hydrogels. The gel successfully encapsulated ASA via electrostatic interactions and achieved sustained release, promoting stem cell proliferation and differentiation. In vivo studies confirmed the potential of this gel in bone tissue engineering.
BIOACTIVE MATERIALS
(2022)
Article
Genetics & Heredity
Sang-Eun Nam, Hye-Jin Eom, Hyoung Sook Park, Jae-Sung Rhee
Summary: In this study, we report the complete mitochondrial genome information of the six-line wrasse Pseudocheilinus hexataenia. The genome is circular with a length of 17,111 bp and exhibits typical Labriformes gene composition. Phylogenetic analysis shows a close relationship between P. hexataenia and the goldsinny wrasse Ctenolabrus rupestris.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Environmental Sciences
Bo-Mi Kim, Yeonhui Lee, Jhee-Yeong Hwang, Young-Ki Kim, Tae Wan Kim, Il-Nam Kim, Seunghyun Kang, Jin-Hyoung Kim, Jae-Sung Rhee
Summary: This study investigated the effects of salinity fluctuations on the Antarctic harpacticoid copepod Tigriopus kingsejongensis, finding that female copepods were more tolerant to hypo- and hypersalinity compared to males. Lifespan was significantly shortened under hypo- and hypersalinity, but there was no significant difference in sex ratio between salinity treatments. Multigenerational experiments showed that exposure to certain salinities reduced body length compared to control.
ENVIRONMENTAL RESEARCH
(2022)
Article
Engineering, Environmental
Bo-Mi Kim, Bomi Kim, Sang-Eun Nam, Hye-Jin Eom, Somyeong Lee, Kitae Kim, Jae-Sung Rhee
Summary: This study found that the toxicity of Cr(VI) reduced by citric acid in ice was significantly lower, resulting in reduced harm to aquatic animals. Animals showed increased tolerance to Cr(VI) after reduction in ice, with no impact on antioxidant capacity.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Genetics & Heredity
Sang-Eun Nam, Hye-Jin Eom, Hyoung Sook Park, Jae-Sung Rhee
Summary: This study presents the complete mitochondrial genome of the rainbow krib and compares it with other cichlid species. The findings contribute to a better understanding of the mitochondrial genome evolution in cichlids and highlight the importance of more complete mitogenomes for further research.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Genetics & Heredity
Sang-Eun Nam, Jaehee Kim, Jae-Sung Rhee
Summary: The complete mitochondrial genome of the freshwater water flea Moina macrocopa was sequenced and annotated, with a length of 16,072 bp. Phylogenomic analysis revealed that M. macrocopa is closely related to members of the Daphniidae family.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Genetics & Heredity
Sang-Eun Nam, Jae-Sung Rhee
Summary: Here, we report the complete mitochondrial genome information of the firemouth cichlid, Thorichthys meeki, and find its close relationship with Thorichthys aureus.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Environmental Sciences
Somyeong Lee, Md. Niamul Haque, Jae -Sung Rhee
Summary: This study evaluated the acute and chronic effects of dichlofluanid, a broad-spectrum fungicide, on the marine mysid Neomysis awatschensis. The results showed higher sensitivity to dichlofluanid in juvenile mysids compared to adults, with lower survival rate and reduction in food consumption. Exposure to dichlofluanid induced oxidative imbalance and affected enzymatic activities. Chronic exposure to sublethal concentrations of dichlofluanid resulted in decreased survival rate in juveniles and growth retardation in multigenerational monitoring. Consistent exposure to environmentally relevant concentrations of dichlofluanid could be detrimental to the mysid population.
ENVIRONMENTAL POLLUTION
(2022)
Review
Biochemistry & Molecular Biology
Sang-Eun Nam, Dae-Yeul Bae, Jang-Seu Ki, Chi-Yong Ahn, Jae-Sung Rhee
Summary: This mini review highlights the power of multi-omics approach in monitoring the health of freshwater animals, while discussing the challenges and limitations in integrating multidimensional datasets.
MOLECULAR & CELLULAR TOXICOLOGY
(2023)
Article
Genetics & Heredity
Sang-Eun Nam, Somyeong Lee, Yeonhui Lee, Jae-Sung Rhee
Summary: In this study, we sequenced and annotated the complete mitochondrial genome of Neoamphitrite affinis, a polychaete worm species. The genome is circular and consists of protein-coding genes, transfer RNA genes, ribosomal RNA genes, and a non-coding region. Phylogenomic analysis confirmed the relationship between N. affinis and the Terebellidae family.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Environmental Sciences
Jaehee Kim, Md Niamul Haque, Somyeong Lee, Do-Hee Lee, Jae-Sung Rhee
Summary: The combined effects of hexavalent chromium and microplastics on aquatic organisms are not well understood. This study found that microplastics can exacerbate the toxicity of hexavalent chromium, leading to decreased survival rates and reproductive ability in aquatic animals.
Article
Genetics & Heredity
Hye-Jin Eom, Jae-Sung Rhee
Summary: We sequenced and annotated the complete mitochondrial genome of the sea-pen Cavernularia obesa (Valenciennes, 1850). The genome is 18,641 bp long with a GC ratio of 34.7%. It contains 13 protein-coding genes, two rRNA genes, 22 tRNA genes, and a non-coding region. Phylogenomic analysis confirmed the published phylogenetic relationship placing C. obesa in the Pennatulacea order within Octocorallia. This mitochondrial genome resource will be valuable for future phylogenetic studies in water fleas.
MITOCHONDRIAL DNA PART B-RESOURCES
(2023)
Article
Biochemistry & Molecular Biology
Jaehee Kim, Yugyeong Sim, Jinyoung Jeong, Jee-Hyun Jung, Jae-Sung Rhee
Summary: This study evaluated the potential harmful effects of fragmented polyvinyl chloride (PVC) on a water flea model. The results showed that PVC fragments can be temporarily bioconcentrated through ingestion and then egested in feces. Higher concentrations of PVC fragments significantly increased mortality and inhibited growth, reproduction, and antioxidant defense.
MOLECULAR & CELLULAR TOXICOLOGY
(2023)
Article
Food Science & Technology
Yun Kyung Shin, Do Yeon Seo, Hye-Jin Eom, Mira Park, Minji Lee, Young-Eun Choi, Young-Seok Han, Jae-Sung Rhee, Youn-Jung Kim
Summary: This study confirms that K. mikimotoi induces oxidative stress and DNA damage in P. major, with gill and blood samples serving as potential biomarkers for detecting the degree of oxidative stress in fish.
Article
Genetics & Heredity
Hayoung Kwon, Hyoung Sook Park, Jae-Sung Rhee
Summary: In this study, the complete mitochondrial genome sequence of P. prolixa was reported. It consisted of 13 protein-coding genes, 22 transfer RNA genes, and 2 ribosomal RNA genes. Phylogenetic analysis confirmed the classification of P. prolixa within the Comatulida family.
MITOCHONDRIAL DNA PART B-RESOURCES
(2023)
Article
Engineering, Marine
Young-Joo Yun, Sung-Ah Kim, Jaehee Kim, Jae-Sung Rhee
Summary: This study analyzed the acute and chronic effects of diuron on the harpacticoid copepod Tigriopus japonicus. The acute exposure experiment showed that 1/10 LC50 diuron significantly reduced the copepod's feeding rate and acetylcholinesterase activity. Chronic exposure revealed adverse multigenerational effects, with the second generation being the most sensitive to diuron.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)