☆ 4.4 Article

Rh(III)-catalyzed [4+1]-annulation of azobenzenes with α- carbonyl sulfoxonium ylides toward 3-acyl-(2H)-indazoles

TETRAHEDRON LETTERS (2018)

Journal

TETRAHEDRON LETTERS

Volume 59, Issue 23, Pages 2284-2287

Publisher

PERGAMON-ELSEVIER SCIENCE LTD

DOI: 10.1016/j.tetlet.2018.05.001

Keywords

Rhodium-catalyzed; Sulfoxonium ylides; 2H-indazoles

Categories

Chemistry, Organic

Funding

National Natural Science Foundation of China [21572025, 21602019]
Innovation & Entrepreneurship Talents Introduction Plan of Jiangsu Province
Natural Science Foundation of Jiangsu Province [BK20171193]
Key University Science Research Project of Jiangsu Province [15KJA150001]
Jiangsu Key Laboratory of Advanced Catalytic Materials Technology [BM2012110]
Advanced Catalysis and Green Manufacturing Collaborative Innovation Center
Young Natural Science Foundation of Jiangsu Province [BK20150263]

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Abstract

A Rh(III) catalyzed [4 + 1] annulation of azobenzenes with alpha- carbonyl sulfoxonium ylides was developed to access 2H-indazoles in moderate to excellent yields with good functional group compatibilities. It proceeded with the sequential insertion of the Rh(III) carbene to the C-H bond and cyclization steps, where sulfoxonium ylides served as efficient and stable carbene precursor. (C) 2018 Published by Elsevier Ltd.

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