Article
Chemistry, Inorganic & Nuclear
Wen Lu, Jichao Chen, Jiuzhou Shi, Zhong Li, Li Xu, Weina Jiang, Shilong Yang, Buhong Gao
Summary: The novel acylhydrazone coumarin fluorescent chemosensor C-4 showed high selectivity and sensitivity towards Ni2+, with a low detection limit of 2.1 x 10(-11) M. It could be successfully applied for the detection of Ni2+ in water samples and demonstrated high potential for investigating biological processes involving Ni2+ in Hela cells.
INORGANICA CHIMICA ACTA
(2021)
Article
Chemistry, Organic
Xianjiao Meng, Jinzhong Zhao, Yongpo Zhang, Zhichun Li, Changchun Yuan, Wenbing Ma
Summary: The novel fluorescent chemosensor 1 showed a significant off-on-off fluorescence response towards Al3+ and pyrophosphate (PPi) in aqueous solution, with detection limits of 0.26 mu mol/L for Al3+ and 0.1 mu mol/L for PPi. The binding stoichiometry was found to be 1:1, and the effective determination pH range for Al3+ and PPi was from 2 to 10, with a cycle response test reaching 4 times.
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xiaojun He, Feng Ding, Xiaoshuai Sun, Yujing Zheng, Wei Xu, Lisong Ye, Hong Chen, Jianliang Shen
Summary: A multifunctional pH probe NNBDH has been developed, which can sensitively sense pH changes in different environments and provide treatment for diseases such as combating the superbug MRSA. This probe has excellent response speed and stability, suitable for water, live cells, and animal tissues.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Alen Sam Thomas, Apurba Pramanik, Sara Amer, Vered Marks, Mindy Levine
Summary: This study reports the design, synthesis, and application of a highly solvatochromic coumarin derivative (compound 1) for water detection. The solvatochromism of compound 1 is attributed to the presence of an electron-withdrawing aldehyde substituent and an electron-donating diethylamino group. Compound 1 shows significant fluorescence responsiveness to polar protic solvents, especially with a pronounced decrease in fluorescence upon the addition of small amounts of water. This water-based responsiveness is utilized in the development of a fluorescent water sensor with rapid, sensitive, and irreversible fluorescence quenching to both liquid water and water vapor.
Article
Chemistry, Physical
Aditya Kumar Purohit, Hemanta K. Kisan, Sumanta Sahu, Pravin Kumar Kar
Summary: A novel Zn(ll)-terpyridine complex was synthesized and used as a selective fluorescent probe for pyrophosphate P2O74- (PPi). The sensing mechanism and properties of the complex were studied through theoretical calculations.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Analytical
Peraya Hiranmartsuwan, Sirilak Wangngae, Jukkrit Nootem, Anyanee Kamkaew, Rathawat Daengngern, Worawat Wattanathana, Kantapat Chansaenpak
Summary: In this study, two pyridylhydrazone-tethered BODIPY compounds were synthesized and characterized. These compounds have the ability to selectively detect hypochlorous acid (HOCl) through a fluorescence turn-on mechanism. In cell imaging experiments, they showed excellent biocompatibility and visualization of endogenous HOCl in living cells.
Article
Spectroscopy
Hong Chen, Jiamin Luo, Shijin Chen, Yueheng Qi, Tong Zhou, Xiumei Tian, Feng Ding
Summary: Researchers have developed a novel dual-functional chemosensor, CMHN, which can sensitively detect changes in HClO and pH. The sensor has been successfully applied in imaging detection of HClO and pH changes in aqueous solutions, live cells, and zebrafish, demonstrating high sensitivity, quick response time, and high selectivity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Jianwei Wu, Chenming Chan, Jia Li, Yaqiao Shi, Zhaoli Xue, Long Zhao
Summary: This study designs and synthesizes a 2,6-substituted BODIPY molecule, LM-BDP, as a fluorescent probe for detecting S2- in aqueous media. The electronic and crystal structures of the probe are studied using density functional theory (DFT) calculations and single-crystal X-ray diffraction analysis. Spectroscopy investigations show that LM-BDP exhibits a noticeable color change from pink to dark red and a fluorescence shift from yellow to pink channel with decreased intensity upon addition of S2-. The probe shows high selectivity and sensitivity with a detection limit of 0.29μM in less than 100 s, and it demonstrates significant fluorescence contrast in test-stripe and RAW 264.7 cell experiments, making it a suitable candidate for detecting exogenous S2-.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Review
Chemistry, Applied
Danish Khan, Shaily
Summary: This article summarizes the application of coumarin probes in the detection of various species. It emphasizes the mechanisms involved and highlights the recent developments in the design of such probes. Additionally, it draws attention to the application protocol and shortcomings of reported coumarin-based fluorescent probes, providing insights for future progress in this field. It is believed that this review can serve as a reference guide for novices and contribute to advancements in biological and chemical research.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Review
Chemistry, Analytical
Soma Sarkar, Abhik Chatterjee, Kinkar Biswas
Summary: In this paper, we have discussed the important modified rhodamine compounds used as chemosensors in the last 7-8 years. The review covers chemosensors for the detection of metal ions such as Al(III), Cu(II), Hg(II), Co(II), Fe(III), Au(III), Cr(III), and anions like CN-. The paper provides a clear description of the selectivity, sensitivity, photophysical properties, binding affinity, limit of detection, and application of these chemosensors. Additionally, functionalized rhodamine-based chemosensors emitting in the near-infrared region and targeting lysosomes for pH detection are discussed, along with their versatile applicability in medicine. The photophysical properties of spirolactam rhodamine photoswitches and their applications in single-molecule localization microscopy and 3D light photoactivable dye displays are also highlighted, along with the real-time detection of radical intermediates.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Spectroscopy
Xiao-Lei Xue, Yang Wang, Hao Zhang, Shaojin Chen, Shu-Yan Niu, Lingyun Cui, Kun-Peng Wang, Zhi-Qiang Hu
Summary: Biothiols such as cysteine, homocysteine, and glutathione, which are important in life activities, have been the subject of recent research on their quantitative tracking and analysis in living organisms. A fluorescent probe called COUN was designed and synthesized for the color recognition of cysteine, homocysteine, and glutathione. The probe specifically recognized homocysteine, showing significant fluorescence enhancement. Moreover, the probe showed good linear relationships with different concentrations of cysteine, homocysteine, and glutathione.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Physical
Chen Zhao, Hongmei Xu, Yating Meng, Yu Wang, Shaomin Shuang, Chuan Dong
Summary: A new fluorescent probe DPHA was designed and synthesized for the sequential detection of aluminum ions and pyrophosphate. DPHA exhibited sensitive fluorescence sensing of Al3+ and overcame interference from other common cations. Due to its good biocompatibility, DPHA showed potential for monitoring metal ions and pyrophosphate in living cells and zebrafish.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Inorganic & Nuclear
Shuyue Ma, Kang-Nan Wang, Miaomiao Xing, Fei Feng, Qiling Pan, Duxia Cao
Summary: A coumarin derivative CBE fluorescent chemosensor was developed for efficient detecting H2O2 in living cells through boronic ester elimination. The probe can specifically recognize H2O2 with high sensitivity and selectivity, providing a rapid response and detection within 16 minutes.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Jorge Espina-Casado, Tania Fontanil, Alfonso Fernandez-Gonzalez, Santiago Cal, Alvaro J. Obaya, Marta Elena Diaz-Garcia, Rosana Badia-Laino
Summary: Carbon dots were synthesized from glutathione and surface-modified with beta-Cyclodextrin and FP, showing potential applications as drug carriers. The fluorescence changes allowed distinction of cancer cells with no alterations in cell morphology, enabling bioimaging and cancer diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Feng Ding, Han Wen, Ruijiang Zhuo, Jiawei Li, Hui Zheng, Yuru Deng, Jianliang Shen, Xiaojun He
Summary: This study presents a novel chemosensor CMTH based on coumarin for highly sensitive and selective detection of HClO in various organisms, with ultrafast response time and good water solubility being its key features.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
