4.4 Article

Direct C(sp3)-H difluoroallylation of diarylmethanes with α-(trifluoromethyl) styrenes at room temperature

Journal

TETRAHEDRON
Volume 74, Issue 31, Pages 4155-4159

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.06.018

Keywords

alpha-(trifluoromethyl)styrenes; gem-difluoroalkenes; Difluoroallylation; Diarylmethanes

Funding

  1. National Natural Science Foundation of China [21472043, 21272070]

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A rapid and convenient method for the synthesis of 3,3-difluoroallylated diarylmethanes by reactions of diarylmethanes with alpha-(trifluoromethyl)styrenes in the presence of LiHMDS at room temperature was developed. (C) 2018 Elsevier Ltd. All rights reserved.

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