Journal
TETRAHEDRON
Volume 74, Issue 10, Pages 1085-1091Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.01.041
Keywords
Benzylic C-H bond; Amination; Hypervalent iodine; Metal-free; N-Fluorobenzenesulfonimide
Categories
Funding
- National Natural Science Foundation of China [21702054]
- Hubei Province Natural Science Foundation [2016CFB206]
- Hubei Provincial Hundred-Talent Program Fund
Ask authors/readers for more resources
A metal-free remote oxidative benzylic C-H amination of 4-methylanilides with N-fluorobenzenesulfonimide was reported. The reaction was promoted by a hypervalent iodine reagent and can be handled under mild and neutral conditions, providing the highly regioselective benzylic C-H amination products even with multi-substituted 4-methylanilides. It provided a novel and facile method for the construction of C(sp(3))-N bonds. (C) 2018 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
