Sinomenine Induces G1-Phase Cell Cycle Arrest and Apoptosis in Malignant Glioma Cells Via Downregulation of Sirtuin 1 and Induction of p53 Acetylation

Cathepsin L knockdown enhances curcumin-mediated inhibition of growth, migration, and invasion of glioma cells

(2016) Yao Fei et al.   BRAIN RESEARCH

Antinociceptive effects of sinomenine in a rat model of postoperative pain

(2016) Qing Zhu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Emerging targeted therapies for glioma

(2016) Julie J Miller et al.   EXPERT OPINION ON EMERGING DRUGS

Sinomenine prevents metastasis of human osteosarcoma cells via S phase arrest and suppression of tumor-related neovascularization and osteolysis through the CXCR4-STAT3 pathway

(2016) TAO XIE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

On-Chip Clonal Analysis of Glioma-Stem-Cell Motility and Therapy Resistance

(2016) Daniel Gallego-Perez et al.   NANO LETTERS

Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling

(2016) Tian Qin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Forkhead Transcription Factor FOXO1 Inhibits Angiogenesis in Gastric Cancer in Relation to SIRT1

(2016) Sue Youn Kim et al.   Cancer Research and Treatment

β-Elemene Selectively Inhibits the Proliferation of Glioma Stem-Like Cells Through the Downregulation of Notch1

(2016) Hai-bin Feng et al.   Stem Cells Translational Medicine

Recent advances in targeted therapy for glioblastoma

(2015) Shivani Mittal et al.   Expert Review of Neurotherapeutics

Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression

(2015) Bilge Debelec-Butuner et al.   Journal of Inflammation-London

SirT1 knockdown potentiates radiation-induced bystander effect through promoting c-Myc activity and thus facilitating ROS accumulation

(2015) Yuexia Xie et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Sinomenine, a COX-2 inhibitor, induces cell cycle arrest and inhibits growth of human colon carcinoma cells in vitro and in vivo

(2015) HAIBO YANG et al.   Oncology Letters

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells

(2015) Michele Dal Bo et al.   Oncotarget

Vascular Normalization Induced by Sinomenine Hydrochloride Results in Suppressed Mammary Tumor Growth and Metastasis

(2015) Huimin Zhang et al.   Scientific Reports

Recent advances in targeted therapy for glioblastoma

(2015) Shivani Mittal et al.   Expert Review of Neurotherapeutics

SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

(2015) Marie Boutant et al.   Molecular Metabolism

SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation

(2014) Melissa J. Wilking et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Suppressive Effect of Sinomenine Combined with 5-Fluorouracil on Colon Carcinoma Cell Growth

(2014) Ji-Xiang Zhang et al.   Asian Pacific Journal of Cancer Prevention

Comparative Pharmacokinetics Study of Sinomenine in Rats after Oral Administration of Sinomenine Monomer and Sinomenium Acutum Extract

(2014) Mao-Fan Zhang et al.   MOLECULES

Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma

(2013) Jing Wang   WORLD JOURNAL OF GASTROENTEROLOGY

SIRT1 promotes proliferation and inhibits apoptosis of human malignant glioma cell lines

(2012) Yan Qu et al.   NEUROSCIENCE LETTERS

Sinomenine Versus NSAIDs for the Treatment of Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

(2008) Min Xu et al.   PLANTA MEDICA