Article
Environmental Sciences
Darren J. Koppel, Gwilym A. Price, Kathryn E. Brown, Merrin S. Adams, Catherine K. King, Damian B. Gore, Dianne F. Jolley
Summary: Metal contaminants in Antarctic soils show varied concentrations and activities in different extraction agents, while the DGT method can provide environmentally relevant measurements of metal contaminant lability.
Article
Biotechnology & Applied Microbiology
Marta Turull, Claudia Fontas, Sergi Diez
Summary: In this study, the effects of two different organic amendments on trace metal transfer from soils to crops were investigated. The addition of compost to soil resulted in lower trace metal concentrations in lettuce compared to soils with no amendment. Biochar also showed a reduction in Cr and Pb uptake by lettuce, with higher levels of biochar leading to greater reductions. The DGT method was found to be faster and more cost-effective in predicting metal uptake by plants compared to BCR sequential extraction.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Engineering, Environmental
Mengke Song, Yicheng Su, Longfei Jiang, Ke Peng, Jinling Li, Sisi Liu, Yingtao Sun, Chang-Er Chen, Chunling Luo
Summary: This study utilized the DGT technique to determine the bioavailability of antibiotics in soil and compared the results with plant uptake, soil solutions, and solvent extraction methods. The results showed that DGT had predictive capability for plant uptake of antibiotics and the bioavailability varied in different soils.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Cheng Yao, Feifei Che, Xia Jiang, Zhihao Wu, Junyi Chen, Kun Wang
Summary: The study revealed that under the influence of pollutants discharged by textile plants, the concentrations of antimony compounds in the sediment of shallow lakes are relatively high. Antimony was found to be immobile in the oxygen-rich layer, but released along with other elements in the anoxic environment, depending on the redox conditions and the labile antimony content in the sediment. The mobility of antimony in shallow lakes and wetland sediments should be carefully considered when assessing the potential ecological risks.
Review
Engineering, Environmental
Yixuan Liang, Hanbing Li, Sumei Li, Sha Chen
Summary: Antibiotics, widely used in human and veterinary medicine, are persistent organic compounds that contribute to the development of antibiotic resistance in microbes. This review discusses the use of o-DGT technology to study the behavior of antibiotics in different environmental media. It compares different agarose diffusive gel and binding agents, explores the feasibility of o-DGT in water and soil, and analyzes the potential of using o-DGT in sediment for antibiotic measurements.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Rachel Martins de Barros, Juliette Rougerie, Robin Guibal, Sophie Lissalde, Remy Buzier, Stephane Simon, Gilles Guibaud
Summary: In this study, the performances of L-DGT, conventional DGT, and POCIS were compared for monitoring organic contaminants. The results showed that L-DGT had advantages in sensitivity and robustness during field deployment compared to the conventional DGT. POCIS had the highest sensitivity, but both L-DGT and DGT provided more reliable determination of time-weighted average concentrations (CW). L-DGT was more suitable for low-contaminated contexts requiring higher sensitivity, while POCIS remained the most suitable passive sampler for qualitative evaluation.
ENVIRONMENTAL POLLUTION
(2023)
Review
Environmental Sciences
Xiaowen Ji, Jonathan K. Challis, Markus Brinkmann
Summary: Diffusive Gradient in Thin Films (DGT) for organics has gained attention for studying chemical dynamics, but faces limitations in outer filter membrane and configuration, requiring further investigation; the impact of biofouling on DGT for organics needs systematic study; using DGT combined with bioassays to predict environmental mixtures' effects on biota shows promise for future research.
Article
Environmental Sciences
Po Wang, Bowen Du, Jayme Smith, Wenjian Lao, Charles S. Wong, Eddy Y. Zeng
Summary: A passive sampler based on organic-diffusive gradients in thin films (o-DGT) was developed for monitoring microcystins (MCs) in waterbodies, showing effectiveness in assessing dissolved MCs. o-DGT demonstrated a lower time-weighted average MC concentration compared to grab sampling, indicating its potential limitations in capturing total MC levels in waterbodies.
Article
Environmental Sciences
Karelys Umbria-Salinas, Astolfo Valero, Monica Wallner-Kersanach, Carlos Ferreira de Andrade, Maria Josefa Santos Yabe, Julio Cesar Wasserman, Katia Naomi Kuroshima, Hao Zhang
Summary: The study assessed seasonal variations in the concentrations of labile fractions of metals in shipyards located in estuarine areas on the Brazilian subtropical coast, indicating shipyards as hotspots of trace metals where Ecological Risk Assessment should be carried out.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Liying Yan, Qiuyu Rong, Hao Zhang, Kevin C. Jones, Yanying Li, Jun Luo
Summary: A new DGT device and analytical technique were developed to sample and quantify glucocorticoids in aquatic systems. The device showed independent performance under various environmental conditions and demonstrated reliability for monitoring glucocorticoids in natural waters. The development of this new technique will contribute to a better understanding of the behavior and fate of these compounds in aquatic environments.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Hamid Pouran, Mohammed Alkasbi, Elma Lahive, Stephen Lofts, Hao Zhang
Summary: The study utilized DGT technique to measure the concentration of ZnO NPs in soils, revealing variations in the dissolution of ZnO NPs and the available concentrations of dissolved and nanoparticulate zinc in different soils.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Hongmei Cao, Qingwei Bu, Qingshan Li, Xiaohong Gao, Huaijun Xie, Wenwen Gong, Xiaoxiao Wang, Lei Yang, Jianfeng Tang
Summary: This study developed passive sampling devices called diffusive gradients in thin films (DGTs) for sampling pharmaceuticals in surface waters. The results showed that the HLB-DGT devices exhibited good performance and their results were comparable to conventional grab sampling. Additionally, the study expanded the monitoring range to include three antiviral drugs used for COVID-19 treatment.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Han Wang, Ben Yu, Baochen Li, Ting Zhao, Yimin Cai, Yongming Luo, Haibo Zhang
Summary: This study found that the addition of PE microplastics in paddy soil and saline soil can promote the degradation of SMX, but has different effects on the bioaccessibility of SMX. The addition of PE microplastics in saline soil significantly reduces the bioaccessibility of SMX and increases the risk of SMX re-release.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Xiaowen Ji, Jonathan K. Challis, Jenna Cantin, Ana S. Cardenas Perez, Yufeng Gong, John P. Giesy, Markus Brinkmann
Summary: Dynamic processes of organic contaminants in sediments have toxicological implications in aquatic systems. The study used DGT devices to measure the flux and exchange rates of antipsychotic compounds in sandy sediments. The results showed the continuous removal of these compounds from the sediments and their movement to the adjacent sediment solution. A dynamic model was used to determine the rate constants and distribution coefficients of the antipsychotics. The study highlights the importance of understanding the desorption kinetics of contaminants in sediments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Siday Marrugo-Madrid, Manuel Salas-Moreno, Harry Gutierrez-Mosquera, Carlos Salazar-Camacho, Jose Marrugo-Negrete, Sergi Diez
Summary: To fulfill the requirements of the Minamata Convention on Mercury, it is important to monitor mercury contamination in freshwater ecosystems near artisanal and small scale gold mining (ASGM) areas. This study examined the feasibility of using the diffusive gradient in thin-films (DGT) technique to detect and quantify labile mercury and other metals in a hard-to-reach gold mining district in Colombia. The results showed that the labile mercury concentrations were higher in abandoned mining ponds compared to the river water, and the labile concentrations of other metals were related to their proximity to ASGM activities.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Marek Reichstadter, Yue Gao, Pavel Divis, Tianhui Ma, Camille Gaulier, Martine Leermakers
Summary: Diffusive gradients in thin-films (DGT) is an in situ passive sampling technique used to assess labile trace metal concentrations in different environmental matrices. Two cysteine-modified resins were developed for the DGT technique, allowing simultaneous determination of labile Hg and other trace metals in a broad range of pH and ionic strength. The higher load of functional groups on the modified resins showed better performance in further DGT applications.
Article
Environmental Sciences
Camille Gaulier, Chunyang Zhou, Yue Gao, Wei Guo, Marek Reichstadter, Tianhui Ma, Willy Baeyens, Gabriel Billon
Summary: This study investigated the biogeochemical behavior of Cd, Co, Cr, Cu, Ni and Pb along the Scheldt estuary, highlighting the variations of trace metal speciation and distribution. The mobility and partitioning of trace metals were mainly driven by biogeochemical reactions influenced by estuarine physicochemical parameters. The study confirmed decreasing trend for particulate metals and rising concentrations for dissolved trace metals along the Scheldt.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Ines Tomasek, Hassina Mouri, Antoine Dille, George Bennett, Prosun Bhattacharya, Natacha Brion, Marc Elskens, Karen Fontijn, Yue Gao, Patrick Kirita Gevera, Julian Ijumulana, Mary Kisaka, Martine Leermakers, Ceven Shemsanga, Kristine Walraevens, Joanna Wragg, Matthieu Kervyn
Summary: This study reports the presence of potentially toxic elements (PTEs) in groundwater in the populated flanks of Mt. Meru in the East African Rift Valley, with most elements within acceptable limits for drinking water. However, some samples exceeded the WHO tolerance limits for Uranium and Molybdenum. The study emphasizes the need to expand monitoring of elements in regional groundwater and more routine measurement of PTEs for water safety and effective management.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Chemistry, Analytical
Yue Gao, Chunyang Zhou, Josep Galceran, Carlos Rey-Castro, Jaume Puy, Willy Baeyens, Martine Leermakers
Summary: This article reviews the application of Diffusive Gradients in Thin-films (DGT) in environmental studies, focusing on oxyanions and platinum group elements (PGEs). It summarizes the recent analytical advances in the development and use of DGT for these target element groups, while also highlighting the remaining knowledge gaps.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Wei Guo, Jun Li, Mingyue Luo, Yan Mao, Xiangyi Yu, Marc Elskens, Willy Baeyens, Yue Gao
Summary: Effluents from sewage treatment plants are a significant source of estrogenic substances in water bodies, and this study assessed the presence of steroids, BPA, and phthalates in the effluents of three urban treatment plants in Beijing. The results showed that the concentrations and activities of estrogenic compounds were lower in the tertiary effluent compared to the secondary effluent. The study also revealed the removal mechanisms for these compounds, with biodegradation playing a significant role for some compounds while others were removed through adsorption and sedimentation.
Article
Environmental Sciences
Vendula Smolikova, Natacha Brion, Tianhui Ma, Vincent Perrot, Yue Gao, Pavlina Pelcova, Andrea Ridoskova, Martine Leermakers
Summary: The distribution and geochemistry of arsenic in water and sediments of the Zenne River, a small urban river in Brussels, were investigated. The study found that arsenic concentrations increase downstream, driven by the tidal cycle. Different arsenic species in water and sediment were assessed using DGT technique, and a point source on the tributary Tangebeek was identified as a major contributor to arsenic load in the Zenne River.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Mingyue Luo, Chunyang Zhou, Tianhui Ma, Wei Guo, Lawrence Percival, Willy Baeyens, Yue Gao
Summary: This study investigated the impact of dumping of dredged sludge, shipyard activities, and the mixing of polluted estuary water with less polluted coastal water on the mobilization of trace metals and oxyanions in marine sediments. The results showed that these anthropogenic activities have a significant influence on the levels, distribution, and bioavailability of contaminants in the sediments, posing a real threat to the benthic ecosystem.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Multidisciplinary Sciences
Sebastiaan J. J. van de Velde, Andrew W. W. Dale, Sandra Arndt
Summary: We developed a model to trace iron isotopes in marine sediments and studied the influence of bioturbation on the isotopic signature of benthic dissolved iron (DFe) flux. The model was fitted with published data, and effective fractionation factors were calibrated to match literature values. Our results showed that higher bioturbation increased the benthic DFe flux and its delta Fe-56 signature for higher oxygen concentrations, but decreased them for lower oxygen concentrations. Bioturbation also increased the sedimentary DFe release and decreased the delta Fe-56 signature on a global scale.
ROYAL SOCIETY OPEN SCIENCE
(2023)
Article
Engineering, Environmental
Jordi Sans-Duno, Joan Cecilia, Josep Galceran, Jaume Puy, Willy Baeyens, Yue Gao
Summary: Determining species, concentrations, and physicochemical parameters in natural waters is important for understanding ecosystem functioning. The use of DGT devices with different thicknesses of the resin or diffusive disc provides independent information on relevant parameters. This study presents a method for determining dissociation rate constants of metal complexes and estimating metal bioavailability in environmental waters.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Biology
Alison T. Cribb, Sebastiaan J. van de Velde, William M. Berelson, David J. Bottjer, Frank A. Corsetti
Summary: The radiation of bioturbation during the Ediacaran-Cambrian transition was hypothesized to increase oxygenation in sediments and promote the expansion of the benthic zone. However, the effects of bioturbation on sediment oxygen are not well-studied. We categorized trace fossils as either biomixing or bioirrigation fossils and used modeling to simulate oxygen penetration depths. Our findings suggest that biomixing was the dominant bioturbation behavior and extensive oxygenation of shallow marine sediments globally is unlikely.
Article
Environmental Sciences
Vincent Perrot, Tianhui Ma, Delphine Vandeputte, Vendula Smolikova, Arne Bratkic, Martine Leermakers, Willy Baeyens, Yue Gao
Summary: This study reports on the species and levels of mercury in the surface waters of the Scheldt Estuary and the Belgian Part of North Sea. The concentration of mercury on suspended particles gradually decreased along the estuary with increasing salinity and was strongly correlated with organic matter content and origin. In the North Sea, a significant fraction of total mercury occurs in a soluble form, potentially available for microorganisms. The results highlight the important contribution of the Scheldt estuary to the mercury budget in North Sea coastal waters and emphasize the need for seasonal monitoring of all mercury species.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Sebastiaan J. van de Velde, Astrid Hylen, Mats Eriksson, Rebecca K. James, Mikhail Y. Kononets, Elizabeth K. Robertson, Per O. J. Hall
Summary: Organic carbon (OC) burial efficiency is a critical parameter for reconstructing past marine primary productivities. Previous belief that sediments underlying oxygen-deficient (anoxic) bottom waters have low respiration rates and high OC burial efficiencies is challenged by novel in situ measurements and reaction-transport modelling. It is found that sediments underlying anoxic bottom waters actually have much higher respiration rates, which indicates that reconstructions of past marine primary productivity might be greatly underestimated in a predominantly anoxic ocean based on OC burial rates.
PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2023)
Article
Environmental Sciences
Tianhui Ma, Willy Baeyens, Martine Leermakers, Vendula Smolikova, Mingyue Luo, Guanlei Li, Delphine Vandeputte, Vincent Perrot, Yue Gao
Summary: The geochemical behavior of metals in water and sediment in the tidal section of the Zenne River in Belgium was investigated. Sampling campaigns were conducted in October 2013 and March 2021 to analyze the metal concentrations under dry and rainy weather conditions. The study found that the Zenner River is a main source for Fe, Mn, Pb, Cr, Ni, and Zn, but other sources, including upstream transport, may explain the behavior of Co, Cd, and Cu during a tidal cycle. The research also highlighted the importance of rainfall and wind gust events in trace metal distribution and the contamination of sediments in the tidal Zenne.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Si -Si Liu, Yu -Wei Jia, Xiao-Yuan Guo, Jian-Liang Zhao, Yue Gao, Andy J. Sweetman, Guang-Guo Ying, Li Xu, Chen Tu, Chang -Er Chen
Summary: In this study, the adsorption and desorption kinetics of triclosan on polystyrene (PS) and polyvinyl chloride (PVC) were investigated using batch experiments and the diffusive gradients in thin-films (DGT) technique. The results showed that both intraparticle diffusion and external liquid film diffusion affected the adsorption and desorption processes. The DGT results indicated some restrictions to the desorption of triclosan from microplastic suspensions. Additionally, pH and ionic strength had significant effects on the supply of triclosan to DGT, either independently or interactively.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Geosciences, Multidisciplinary
Sebastiaan J. van de Velde, Dominik Hulse, Christopher T. Reinhard, Andy Ridgwell
Summary: The coupled biogeochemical cycles of iron and sulfur are crucial for the long-term evolution of Earth's oceans, impacting the cycling and bioavailability of iron and phosphate. Even with modern-like oxygen levels, the ocean episodically develops euxinic or ferruginous conditions.
GEOSCIENTIFIC MODEL DEVELOPMENT
(2021)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
