Article
Multidisciplinary Sciences
Nupur Mittal, Aniket Saha, Viswatej Avutu, Varun Monga, David R. Freyer, Michael Roth
Summary: Enrollment of adolescent and young adult (AYA) in cancer clinical trials (CCT) is not optimal, with various barriers and facilitators identified. Improving coordination between pediatric and medical oncology, providing supportive research infrastructure, and having advocates may help increase AYA enrollment in clinical trials.
SCIENTIFIC REPORTS
(2022)
Review
Cardiac & Cardiovascular Systems
Josep Redon, Tomas Seeman, Denes Pall, Lagle Suurorg, Konstantinos Kamperis, Serap Erdine, Elke Wuehl, Giuseppe Mancia
Summary: The current knowledge on antihypertensive pharmacological treatment in children and adolescents is still limited, with a focus on mixed cohorts of children with primary and secondary hypertension, and a lack of studies assessing the effect of antihypertensive drugs on hypertensive organ damage.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Oncology
Vidya Puthenpura, Lingyun Ji, Xinxin Xu, Michael E. E. Roth, David R. R. Freyer, A. Lindsay Frazier, Asher M. M. Marks, Farzana D. D. Pashankar
Summary: This study identified higher rates of loss to follow-up among young patients, racial and ethnic minorities, and residents of low socioeconomic status areas participating in pediatric cancer clinical trials. Targeted interventions are needed to ensure equitable follow-up and improved assessment of long-term outcomes.
Article
Hematology
Yannis K. Valtis, Kristen E. Stevenson, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Giacomo Gotti, Andrew M. Brunner, Mary Nauffal, Daniel J. DeAngelo, Marlise R. Luskin
Summary: Adolescent and young adult patients with acute lymphoblastic leukemia have better outcomes when treated on pediatric regimens. However, these regimens increase the risk of osteonecrosis and fractures, especially in younger patients. Recent protocols using pegaspargase may further increase the risk of osteonecrosis. Surgical intervention improves the overall survival of patients with osteonecrosis.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyunjoo Song, Seungjae Lee, Ji Hoon Park, Hae Young Kim, Hooney Daniel Min, Jong-June Jeon, Kyoung Ho Lee
Summary: This study aimed to investigate whether patient triaging with scoring systems can reduce CT use for adolescents and young adults suspected of having appendicitis. The results showed that using clinical scoring systems for selective CT use led to a considerable loss of diagnostic accuracy, with no reduction in CT use when targeting specific sensitivity and specificity values.
Article
Oncology
Renata Abrahao, Elysia M. Alvarez, Austin R. Waters, Crystal C. Romero, Melissa M. Gosdin, Hiba Naz, Brad H. Pollock, Anne C. Kirchhoff, Theresa H. M. Keegan
Summary: Efforts to increase participation of adolescents and young adults (AYAs) in cancer clinical trials (CTs) have been met with low enrollment rates. Barriers identified by oncologists include lack of available CTs, strict eligibility criteria, lack of awareness of open CTs, and poor communication between pediatric and adult oncologists. AYAs report financial and psychosocial barriers, lack of understanding of CTs, and their benefits as obstacles to enrollment. Improved availability of CTs, increased awareness, better communication, and comprehensive support are seen as key strategies to enhance AYA enrollment in CTs.
PEDIATRIC BLOOD & CANCER
(2022)
Article
Psychology, Developmental
Molly J. Richards, Amanda Bogart, Jeanelle Sheeder
Summary: The purpose of this study is to evaluate how adolescents and young adults learn about sexual consent and how they communicate and interpret sexual consent and refusal. The results indicate that there are differences in how males and females express and interpret consent and refusal. Education about sexual consent should incorporate real-life communication practices to prevent sexual assault and promote healthy relationships.
JOURNAL OF ADOLESCENT HEALTH
(2022)
Article
Oncology
M. Soleimani, C. Kollmannsberger, A. Bates, B. Leung, Cheryl Ho
Summary: The study finds that AYA with testicular cancer have unique needs and report more anxiety symptoms in emotional, informational, and practical concerns.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Cell Biology
Jun Ah Lee, Jiwon Lim, Hye Young Jin, Meerim Park, Hyeon Jin Park, Jong Woong Park, June Hyuk Kim, Hyun Guy Kang, Young-Joo Won
Summary: The study compared the clinical features and survival rates of osteosarcoma in adolescents and young adults (AYA) with other age groups. It found that AYA had the highest male-to-female ratio, with most tumors located in extremities. The treatment mainly consisted of local treatment and systemic chemotherapy, and the 5-year overall survival rate of AYA was closer to that of children.
Article
Oncology
Mollie R. Canzona, David E. Victorson, Karly Murphy, Marla L. Clayman, Bonnie Patel, Nicole Puccinelli-Ortega, Thomas W. McLean, Onengiya Harry, Denisha Little-Greene, John M. Salsman
Summary: This study aimed to construct a conceptual model of FC among AYAs with cancer, identifying 13 characteristic themes grouped into four domains to guide future measurement development. The findings highlight the importance of affective experiences, communication factors, and timing factors in shaping AYAs' fertility and fertility preservation experiences.
Article
Education & Educational Research
Ge Wei
Summary: This narrative inquiry focuses on the evolving professional identities of Ping, an experienced Chinese teacher, using the concept of "perezhivanie" to analyze the interconnectedness between intellectual-rational and social-political dimensions. Through narrative inquiry, three images are used to illustrate Ping's construction of her teacher identities, highlighting the impact of her experiences on becoming and being a teacher. The emergence of an imagined professional identity from Ping's accounts has significant implications for teacher education and reform policies in a changing society.
TEACHING AND TEACHER EDUCATION
(2021)
Article
Oncology
Bryan A. Sisk, Megan Keenan, Ginny L. Schulz, Erica Kaye, Justin N. Baker, Jennifer W. Mack, James M. DuBois
Summary: This study identified eight interdependent communication functions in adolescent and young adult (AYA) oncology based on interviews with 37 AYA cancer patients. The findings highlighted the integral role of parents in communication and can be used by clinicians to improve communication experiences for AYA patients.
PEDIATRIC BLOOD & CANCER
(2022)
Article
Psychiatry
Alexander Eckert, Matthias Domhardt, Christina Reinauer, Gabriele Berger, Angela Galler, Andreas Boeckmann, Martina Henn, Thomas Haak, Reinhard W. Holl
Summary: This study aimed to investigate the relationship between NSSI and T1D, revealing that NSSI is significantly correlated with worse diabetes outcomes in adolescent T1D patients. Increased awareness is needed for NSSI in the care of adolescents and young adults with T1D.
PSYCHIATRY RESEARCH
(2021)
Review
Family Studies
Teghan Leech, Diana Dorstyn, Amanda Taylor, Wenjing Li
Summary: Smartphone apps show promise as a stand-alone self-management tool in mental health service delivery, producing significant symptom improvement. While longer-term benefits are still uncertain, some individual studies show positive trends up to 6 months post. Further controlled trials with follow-up data are needed to confirm these findings.
CHILDREN AND YOUTH SERVICES REVIEW
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Faiez Zannad, Cynthia Chauhan, Patrick O. Gee, Nick Hartshorne-Evans, Adrian F. Hernandez, Marilyn K. Mann, Robin Martinez, Roxana Mehran
Summary: Patients are crucial end-users in medical therapies and should be actively involved as contributors and decision-makers throughout the product development process. While there is increasing recognition of this, cardiovascular research lags behind in terms of patient involvement and awareness of clinical trials in the field.
EUROPEAN HEART JOURNAL
(2022)
Article
Oncology
Lyndel Moore, Lauren Matheson, Jo Brett, Verna Lavender, Anne Kendall, Bernadette Lavery, Eila Watson
Summary: Most participants had positive views on patient-initiated follow-up (PIFU) pathways, but a significant minority faced uncertainties and difficulties in accessing ongoing care, performing breast self-examination, managing treatment side-effects, and fear of recurrence. The study highlighted the importance of education on BSE and recognizing signs of recurrence, effective information sharing about side effects, personalized care preferences, and emotional wellbeing on PIFU.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Hospitality, Leisure, Sport & Tourism
Peter Lugosi, Colette O'Brien, Hossein Olya, Ryan C. Pink, Verna Lavender
Summary: This study examines the impact of physical servicescape dimensions and ambient conditions on visitor satisfaction in a cancer treatment context. A case study strategy was adopted in a UK hospital's cancer and haematology clinic, using discussions with clinical staff, observations, and a survey. Ambient conditions were found to have a greater influence on satisfaction compared to design and layout. Wayfinding and privacy features were shown to significantly affect satisfaction. Managing these dimensions can compensate for deficiencies in other areas of the physical servicescape.
INTERNATIONAL JOURNAL OF HOSPITALITY MANAGEMENT
(2023)
Article
Medicine, General & Internal
Susie Aldiss, Faith Gibson, Cecilia Vindrola-Padros, Jo Wray, Paula Kelly
Summary: Despite lower rates of illness, morbidity, and mortality in children during the COVID-19 pandemic, their health and well-being have been significantly impacted, especially during hospitalization. This study investigated the perceptions of hospital staff on the impact of COVID-19 on aspects of care delivery, preparedness, and staffing specific to a specialist children's hospital. The findings highlighted the importance of family involvement in children's healthcare during the pandemic.
Review
Medicine, General & Internal
Jenny Harris, Emma Ream, Jo Armes, Faith Gibson, Afrodita Marcu, Catherine Treena Parsons, Ann Robinson, Sherin Varghese, Karen Poole
Summary: This study aimed to investigate the psychosocial issues affecting women with cancer during pregnancy and their partners, determine available supportive care or educational interventions, and identify knowledge gaps for future research. Twelve studies were included, highlighting the need for further research on the long-term psychosocial impact of cancer on women and their families.
Article
Nutrition & Dietetics
James Evans, Dan Green, Faith Gibson, Graeme O'Connor, Julie Lanigan
Summary: This study compared the complications, nutritional and clinical outcomes of gastrostomies and nasogastric tubes in pediatric bone marrow transplant patients, and found that gastrostomies were safe and effective alternatives.
CLINICAL NUTRITION ESPEN
(2023)
Review
Respiratory System
George Peat, Sally-Ann Delaney, Faith Gibson, Lorna K. Fraser, Joe Brierley
Summary: This systematic review and qualitative evidence synthesis aimed to clarify what shared decision-making constitutes in relation to long-term ventilation initiation for children and young people. The findings from 13 studies clarify the components and approaches supportive of shared decision-making in discussions about long-term ventilation. This review provides a valuable resource to implement shared decision-making practices in the context of long-term ventilation decisions for children and young people.
EUROPEAN RESPIRATORY REVIEW
(2023)
Article
Psychology, Educational
Kate Oulton, Faith Gibson, Charlotte Kenten, Jessica Russell, Lucinda Carr, Angela Hassiotis, Paula Kelly, Sam Kerry, Irene Tuffrey-Wijne, Mark Whiting, Jo Wray
Summary: This study aimed to explore the emotional and physical impact on children and young people with intellectual disabilities when coming into the hospital. Through interviews, surveys, and photography, it revealed the challenges and needs they face, highlighting the importance of individualized care.
JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES
(2023)
Review
Medicine, General & Internal
Priya Patel, Paula D. Robinson, Patrick van der Torre, Deborah Tomlinson, Jennifer Seelisch, Sapna Oberoi, Jessica E. Morgan, Pamela S. Hinds, Miriam Goette, Faith Gibson, Nathan Duong, Hailey Davis, S. Nicole Culos-Reed, Danielle Cataudella, Vanessa Miranda, L. Lee Dupuis, Lillian Sung
Summary: The objective of this study was to update a clinical practice guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients. The results showed that physical activity significantly reduced fatigue, and the panel recommended the use of relaxation, mindfulness, or both to manage fatigue in pediatric patients.
Review
Oncology
Alison Finch, Silvie Cooper, Rosalind Raine, Rachel M. Taylor, Faith Gibson
Summary: Ambulatory Care (AC), introduced in the UK National Health Service in 2004, allows patients to receive inpatient cancer treatment on an outpatient basis. This scoping review aims to understand the origins of the clinical pathway and explore the drivers for the development of AC in the UK. Financial considerations, bed capacity optimization, advances in technology and supportive care, and professional motivation to improve patient experience were identified as the main drivers for AC.
EUROPEAN JOURNAL OF CANCER CARE
(2023)
Review
Oncology
Connor Evans, Lucy Shepherd, Gemma Bryan, Helen Fulbright, Scott Crowther, Sara Wakeling, Andy Stewart, Claire Stewart, Julia Chisholm, Faith Gibson, Bob Phillips, Jessica Morgan
Summary: This systematic review focuses on early phase studies of pediatric relapsed/refractory rhabdomyosarcoma, aiming to provide accurate information for future research and assist families and clinicians in making difficult treatment choices. The review reveals poor outcomes for children participating in early phase studies for relapsed/refractory rhabdomyosarcoma, emphasizing the need for improved reporting quality and consistency.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Meeting Abstract
Oncology
James Evans, Dan Green, Graeme O'Connor, Julie Lanigan, Faith Gibson
PEDIATRIC BLOOD & CANCER
(2022)
Meeting Abstract
Oncology
Faith Gibson, Gemma Bryan, Jess Morgan, Bob Phillips, Susie Aldiss
PEDIATRIC BLOOD & CANCER
(2022)
Meeting Abstract
Oncology
Katie Powers, Jac Airdrie, Sophie Thomas, Faith Gibson, Chloe Geagan, Nic Davies, Sam Malins
Meeting Abstract
Oncology
Jac Airdrie, Chloe Geagan, Nicholas Davies, Katie Powers, Ingram Wright, Heather Borrill, Faith Gibson, Steve Clifford, Stephen Lowis, Simon Bailey, Jennifer Limond, Ray Owen, Richard Grundy, James Lemon, Louise Hayes, Sam Malins, Sophie Thomas
Article
Public, Environmental & Occupational Health
Ana Martins, Susie Aldiss, Rachel M. Taylor, Faith Gibson
Summary: This study aimed to evaluate the key worker role in principal treatment centers for children with cancer in England, Wales, and Scotland. Data was gathered through questionnaires, interviews, focus groups, and reports over a two-year period. The effectiveness of key workers was found to revolve around care coordination, expert knowledge, and relationships, which were vital for improving family experience and delivering individualized care.
INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH AND WELL-BEING
(2022)
