Article
Chemistry, Physical
Rusiri Rathnasekara, Grant Mayberry, Parameswar Hari
Summary: In this study, the thermoelectric, electrochemical, and dielectric properties of four different ZnO morphologies were investigated. ZnO nanorods exhibited the most favorable properties in terms of thermoelectric, electrochemical, and dielectric performance.
Article
Chemistry, Physical
Muhammad Shafa, Iqbal Ahmad, Shahid Hussain, Muhammad Asif, Yi Pan, Rustem Zairov, Asma A. Alothman, Mohamed Ouladsmane, Zahid Ullah, Nabi Ullah, Chen Lai, Uzma Jabeen
Summary: A nanoalloy-based electrochemical sensor for H2O2 detection has been fabricated using chemical reduction methodology. The prepared samples were characterized by X-ray diffraction and scanning electron microscopy. Among all the compositions, Ag-Cu (9:1) nanoalloys showed the best performance in detecting H2O2.
SURFACES AND INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Rizwan Wahab, Manawwer Alam
Summary: This study utilized aluminum oxide quantum dots (γ-Al2O3QDs) for concentration-based analysis of hydrogen peroxide (H2O2). The γ-Al2O3 was synthesized through a hydrothermal solution process and characterized in detail. The γ-Al2O3 QDs were employed for the detection of H2O2 and their sensing efficiency was evaluated with a three-electrode system.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2023)
Article
Chemistry, Analytical
Fikret Ari, Bahar Ince, Mehmet Altay Unal, Mustafa Kemal Sezginturk, Sibel A. Ozkan
Summary: Although there is still room for improvement in diagnostic and treatment options for various cancers, electrochemical biosensors using quartz tuning forks (QTF) have emerged as a promising platform. This research explores the functionalization and isolation of QTF for biomarker determination, demonstrating their unique response and sensitivity. The results show that QTF-based immunosensors have high detection sensitivity and low cost, making them ideal for point-of-care diagnostic devices.
MICROCHEMICAL JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
Roma Agrahari, Radha Rani
Summary: A litre-scale multi-modular microbial fuel cell was operated using exo-electrogenic inoculum enriched from cow-dung for 45 days in batch mode, under three different circuit connections. Electrochemical analysis showed that the individual circuit had the highest power output and the lowest internal resistance. Additionally, the study reported COD removal rate and columbic efficiency of the MFC.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Materials Science, Multidisciplinary
Naseem Akhtar, Malika Rani, Arshad Mahmood, Kashmala Tariq, G. Murtaza, Asma A. Alothman, Rahaf S. AL-zahrani, Sajid Ali, Naveed Kasuar Janjua, Aqeel Shah
Summary: This work successfully synthesized NaCr2O4/GO nanocomposite using co-precipitation method for energy storage applications. Characterizations such as SEM and XRD were performed to investigate the optical and structural properties. The nanocomposite showed reduced crystalline size and high specific capacitance, making it suitable for various applications.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Chemistry, Analytical
Karen Y. P. S. Avelino, Alberto G. Silva-Junior, Maira G. R. Pitta, Abdelhamid Errachid, Maria D. L. Oliveira, Cesar A. S. Andrade
Summary: Systemic sclerosis (SSc) is an autoimmune disease that affects connective tissue. A nano-engineered immunosensor surface was developed for detecting the oncostatin M receptor (sOSMR) protein in clinical samples. The biosensor showed a differential diagnostic character for limited cutaneous (lSSc) and diffuse cutaneous (dSSc) SSc subtypes. The sensing strategy demonstrated high sensitivity and potential for SSc-related biomarker research.
Article
Engineering, Electrical & Electronic
Saima Kaleem, Shahid Mehmood, Madeeha Chaudhry, Awais Ali, Muhammad Fahad Bhopal, Arshad Saleem Bhatti
Summary: Digoxin, a commonly used medication for heart conditions, requires strict monitoring due to its narrow therapeutic range. This study developed a sensitive detection method using Au-NPs and GO composites for digoxin. The electrochemical sensor showed promising performance for future digoxin drug detection applications.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Energy & Fuels
Rubia Shafique, Malika Rani, Arshad Mahmood, Razan A. Alshgari, Kiran Batool, Tahira Yaqoob, Naveed Kausar Janjua, Safia Khan, Shamim Khan, Ghulam Murtaza
Summary: A novel method of synthesizing MXene/CoCr2O4 nanoelectrode material with high stability and conductivity has been reported. The optimized nanocomposite shows superior electrochemical performance in alkaline electrolyte, indicating its potential applications in electrochemical devices such as supercapacitors.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Article
Chemistry, Physical
Anbazhagan Murugan, Vadivel Siva, Abdul Samad Shameem, Sultan Asath Bahadur
Summary: Nano-crystalline quaternary Cu2ZnSnS4 (CZTS) thin films were deposited on conducting and nonconducting substrates using the SILAR method with varying dipping times. The films were characterized structurally, vibrationally, optically, morphologically, compositionally, and electrochemically. The films exhibited a mingled phase of wurtzite and kesterite structures, with good optical absorption and a wide range of bandgap values.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Litun Swain, Gurudas Pakhui, Ashish Jain, Suddhasattwa Ghosh
Summary: This study analyzed the purification of LiCl-KCl eutectic melt by chlorine and the effect of LiCl-KCl + xwt.% H2O prepared by thermal equilibration of eutectic mixture with H2O at 500 degrees C on the moisture content. The analysis was done using acid-base titration and electrochemical impedance spectroscopy (EIS) at an inert tungsten electrode. The study found that the cathodic reduction of H2O led to the formation of OH- film, which contributed to capacitive response and resistance to other faradaic processes. Additionally, the study explored the anodic dissolution of a uranium electrode in LiCl-KCl eutectic melts using EIS.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
S. Blessi, Ayyar Manikandan, S. Anand, M. M. L. Sonia, V. Maria Vinosel, P. Paulraj, Y. Slimani, M. A. Almessiere, M. Iqbal, S. Guner, A. Baykal
Summary: This study analyzed the effect of zinc substitution on mesoporous tin dioxide nanoparticles, revealing improvements in crystallite size, surface area, and electrochemical performance after zinc doping.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Analytical
Litun Swain, Gurudas Pakhui, Ashish Jain, Suddhasattwa Ghosh
Summary: At 500 degrees C, the voltammetric response of LiCl-KCl eutectic melts containing H2O impurity exhibits complex electrochemical characteristics involving Faradaic and non-Faradaic processes. Characterization and analysis of the melts require the use of electrochemical impedance spectroscopy and acid-base titration method.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
M. Hasheena, A. Ratnamala, M. Noorjahan, G. Deepthi Reddy, K. Shiprath, H. Manjunatha, K. Chandra Babu Naidu
Summary: This work focuses on the design and fabrication of a selective and sensitive electrochemical sensor for the detection of the neurotransmitter drug dopamine. The SnS-C quantum dots were synthesized using a microwave irradiation approach and characterized using various techniques. The performance of the modified electrodes was investigated using electrochemical testing methods, and it was found that the sensor exhibited a low LOD of 30 nM and high selectivity.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2022)
Article
Chemistry, Analytical
H. T. Purushothama, Y. Arthoba Nayaka, K. V. Basavarajappa, R. O. Yathisha, P. Manjunatha, M. M. Vinay
Summary: An electrochemical sensor using PR-PGE has been developed for the selective and sensitive determination of Atenolol, with optimized parameters and analytical performance demonstrated in pharmaceutical samples.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Review
Instruments & Instrumentation
E. Akanny, A. Bonhomme, F. Bessueille, S. Bourgeois, C. Bordes
Summary: SERS technique has been widely used in bacteria analysis, offering advantages in terms of analysis time, sensitivity, and sample preparation compared to traditional bacteria culture methods. Over the past 20 years, various SERS methods have been developed for bacteria analysis, with a comprehensive study of related technical issues.
APPLIED SPECTROSCOPY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Meryem Belkilani, Maryam Shokouhi, Carole Farre, Yves Chevalier, Sylvain Minot, Francois Bessueille, Adnane Abdelghani, Nicole Jaffrezic-Renault, Carole Chaix
Summary: The interactions between mono-rhamnolipids and model membranes were studied using a biomimetic approach and multiparametric surface plasmon resonance (MP-SPR) technique. The results demonstrated the efficiency of the MP-SPR technique in detecting and measuring the binding of rhamnolipids to phospholipid liposomes.
Article
Chemistry, Medicinal
Federico Capuana, Alkystis Phinikaridou, Rachele Stefania, Sergio Padovan, Begona Lavin, Sara Lacerda, Eyad Almouazen, Yves Chevalier, Laurence Heinrich-Balard, Rene M. Botnar, Silvio Aime, Giuseppe Digilio
Summary: The use of Gd-4-TESMA, a tetrameric probe specifically designed for molecular imaging of tropoelastin within atherosclerotic plaques, shows great promise in enhancing the characterization of plaque progression compared to monomeric counterparts.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Biophysics
Emna Moujehed, Zied Zarai, Haifa Khemir, Neila Miled, Mohamed Salah Bchir, Corinne Gablin, Francois Bessueille, Anne Bonhomme, Didier Leonard, Frederic Carriere, Ahmed Aloulou
Summary: The study showed that using LIP2 lipase from Yarrowia lipolytica (YLLIP2) can effectively degrease sheepskins, reducing the need for harmful chemicals in the leather industry. The enzymatic treatment produced higher quality leather compared to chemical treatment, with cleaner effluent physicochemical parameters. This opens up new possibilities for a more efficient and environmentally friendly approach in leather production.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Mili Khawla, Hsine Zouhour, Chevalier Yves, Hbaieb Souhaira, Mlika Rym
Summary: X-ZnS quantum dots were synthesized in aqueous solution with excellent properties for detecting tetracycline, and MPA-ZnS QDs showed a larger linear range and a lower limit of detection compared to MPS-ZnS QDs.
Article
Nanoscience & Nanotechnology
Meryem Belkilani, Carole Farre, Yves Chevalier, Sylvain Minot, Francois Bessueille, Adnane Abdelghani, Nicole Jaffrezic-Renault, Carole Chaix
Summary: In this study, a phospholipid-based liposome layer was used as a biomimetic membrane model to investigate the binding between the pH-dependent fusogenic peptide from the influenza virus and the liposomes. The interaction was monitored using a multiparameter surface plasmon resonance approach, and it was found that the peptide could enter the lipid bilayer of liposomes at acidic pH, inducing vesicle swelling, while no insertion of the peptide was observed at alkaline pH, causing liposome contraction.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Chemical
Barthelemy Brunier, Yves Chevalier, Elodie Bourgeat-Lami, Nida Sheibat-Othman
Summary: This study investigates particle nucleation in surfactant-free emulsion polymerization of styrene using Laponite clay as a Pickering stabilizer. The effective number of clay platelets contributing to the surface charge of the polymer particles is calculated to estimate their stabilizing efficiency. A coagulative nucleation mechanism is proposed, and the coagulation coefficient is calculated using the Derjaguin-Landau-Verwey-Overbeek theory. The Hamaker constant involved in the attractive potential of the clay-polymer composite particles is measured experimentally. The model fits the experimental data regarding the number of nucleated particles and the nucleation period. It is found that a higher effective number of clay platelets is needed for surface charge than for full polymer latex surface coverage at the end of nucleation. Moreover, efficient stabilization against coagulation requires almost complete coverage.
MACROMOLECULAR REACTION ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Antoine Bard, Sylvain Minot, Clementine Symonds, Jean-Michel Benoit, Alban Gassenq, Francois Bessueille, Bruno Andrioletti, Camilo Perez, Kevin Chevrier, Yannick De Wilde, Valentina Krachmalnicoff, Joel Bellessa
Summary: A new method of hybridizing two materials and transferring energy through a surface plasmon over micrometric distances is proposed in this paper. The energy transfer mechanism is observed and evaluated through experiments.
ADVANCED OPTICAL MATERIALS
(2022)
Article
Chemistry, Analytical
Pouyan Razmshoar, S. Hajir Bahrami, Mohammad Rabiee, Isaac A. M. Frias, Marie Hangouet, Marie Martin, Francois Bessueille, Abdelhamid Errachid, Nicole Jaffrezic-Renault
Summary: A study was conducted to develop an impedimetric immunosensor for the detection of interleukin-10 cytokine using electrospun polystyrene fibers and polyamidoamine dendritic polymer on a gold electrode. Experimental results showed that the immunosensor exhibited good sensitivity, selectivity, and stability.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Polymer Science
Merymene Boukadida, Najeh Jaoued-Grayaa, Amira Anene, Yves Chevalier, Souhaira Hbaieb
Summary: The study investigates the ability of molecularly imprinted polymers (MIPs) with flexible cross-linking agents to selectively uptake guest molecules. New polyacrylamide polymers were synthesized for histamine (HA) extraction using MIPs immobilized on silica surface (SiO2). The prepared MIPs showed a strong absorption capacity for HA, with MIP4 made with the BA(4) cross-linker demonstrating higher selectivity compared to other MIPs. The Langmuir-Volmer and Volmer models accurately fit the adsorption isotherms and provide thermodynamic parameters. The higher performance of MIP4 is attributed to a higher density of molecular imprints and moderate flexibility of the material.
Article
Chemistry, Analytical
Sylvain Minot, Corinne Gablin, Alban Gassenq, Antoine Bard, Clementine Symonds, Jean -Michel Benoit, Joel Ballessa, Didier Leonard, Francois Bessueille
Summary: Layer-by-layer self-assembly and micro-nanostructured surface preparation techniques can be combined to achieve dye transfer, and surface analysis imaging techniques can provide valuable information for the development of this process.
Article
Pharmacology & Pharmacy
Melissa Marques Goncalves, Daniela Florencio Maluf, Roberto Pontarolo, Cyro Ketzer Saul, Eyad Almouazen, Yves Chevalier
Summary: The nanoprecipitation of hydrogel nanoparticles by complex coacervation was studied using the chitosan-polyphosphate pair of polyelectrolytes at pH 4. Different polyphosphates with varying molar masses and electrical charges were investigated as alternatives to tripolyphosphate. By inverting the order of mixing, negatively charged nanoparticles with diameters of 100-200 nm could be precipitated. This charge inversion allowed for more efficient encapsulation of positively charged proteins, such as bovine serum albumin.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Crystallography
Jean Tallon, Barbara Browning, Emilie Gagniere, Claire Bordes, Franck Bardin, Geraldine Agusti, Yves Chevalier, Melaz Tayakout
Summary: In this study, the phase transition of amorphous calcium carbonate to crystalline forms was investigated in a water/oil emulsion. The effects of different acid types and the addition of 12-hydroxystearic acid (HSA) were examined on the transition kinetics and crystal habits. It was found that an acidic environment accelerated the transition kinetics, while the presence of HSA hindered the transition and led to the formation of elongated rod-shaped crystals and less stable vaterite crystals.
JOURNAL OF CRYSTAL GROWTH
(2023)
Article
Chemistry, Physical
Mathis Benyaya, Marie-Alexandrine Bolzinger, Yves Chevalier, Salome Ensenat, Claire Bordes
Summary: To address health and ecological concerns, the cosmetic and pharmaceutical industries are seeking to design surfactant-free emulsions. Pickering emulsions, stabilized by colloidal particles, show promise in this regard. This article explores the use of three different types of particles (neutral, anionic, and cationic), either alone or in binary mixtures, as stabilizers for Pickering emulsions. The study focuses on the influence of particle charge on emulsion properties and the synergies between different types of particles.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
