Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 254, Issue -, Pages 1069-1077Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2017.07.172
Keywords
Postsynthetic modification; Metal organic framework; Fluorescent probe; pH; Biocompatibility
Funding
- National Natural Science Foundation of China [51372221, 51472217, 51432001, 51632008, U1609219]
- Zhejiang Provincial Natural Science Foundation of China [LZ15E020001]
Ask authors/readers for more resources
A fluorescent pH sensor based on post-synthetically modified nanoscale UiO-67-bpydc by encapsulating Eu3+ cations in the pores was fabricated. The Eu3+ incorporated sample (Eu3+@UiO-67-bpydc) shows excellent luminescence due to the sensitization and protection provided by the parented framework. Subsequently, Eu3+@UiO-67-bpydc was developed as a pH sensor. Eu3+@UiO-67-bpydc shows good chemical resistance to both acidity and alkalinity solutions with pH ranging from 1.06 to 10.99, which makes it potentially useful for wide-range pH sensor. In addition, cycling experiments have demonstrated the utilizability of the sensor. The MU analysis shows that Eu3+@UiO-67-bpydc possesses favourable biocompatibility. Furthermore, fluorescence imaging of Eu3+@UiO-67-bpydc in PC12 cells was also performed to test its feasibility in vivo. Given its exceptional stability and pH-dependent fluorescent intensity, the fluorescent probe should be a promising candidate for application in fluorescent pH sensing in vitro and in vivo. (C) 2017 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available