Article
Chemistry, Inorganic & Nuclear
Lixin Zhang, Congli Wang, Hongfang Jiu, Qianwen Xu, Xin Li, Wei Song, Shiyu Luo, Jiahui Zhao
Summary: In this study, a closely packed carbon-encapsulated CuO/Cu2O heterohedron catalyst with remarkable catalytic activity and stability was reported for the hydrogen evolution reaction in alkaline media.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Physical
Huan Chen, Lei Shao, Junchao Ma, Wenxiu He, Bing Zhang, Xu Zhai, Yu Fu
Summary: Hierarchical hollow CuO/Cu2O and Cu2O/Cu/C composites are successfully constructed by calcining hierarchical tubular MOF in different atmospheres. The as-prepared hollow CuO/Cu2O is composed of nanosheets with a diameter of 20-30 nm, while the hierarchical hollow Cu2O/Cu/C is composed of larger particles with a diameter of about 65 nm. Selecting suitable MOF as sacrificed template and calcining in effective atmosphere provide a facile strategy for constructing derivant with functional structures and increased properties.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Materials Science, Multidisciplinary
Xingwen Zhou, Wei Guo, Yu Yao, Ran Peng, Peng Peng
Summary: This study presents a method for one-step fabrication of integrated sensor's working electrode and electrical contacts on a flexible substrate through laser writing of a low-cost Cu ionic precursor. The obtained Cu2O/Cu porous structure has low sheet resistance for signal transmission and remarkable sensing performance for glucose detection, showing potential for directly detecting trace amounts of glucose in body fluids.
ADVANCED ENGINEERING MATERIALS
(2021)
Article
Chemistry, Analytical
Lu Fang, Yu Cai, Bobo Huang, Qingpeng Cao, Qin Zhu, Tingting Tu, Xuesong Ye, Bo Liang
Summary: A highly sensitive nonenzymatic glucose sensor based on Cu/Cu2O composite nanoparticles was developed, showing improved performance and reliability by decorating the nanoparticles on a single carbon fiber. The sensor exhibited good anti-interference ability, long-time stability, and potential applications in clinical diagnosis and health monitoring.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Fangzhao Pu, Huanran Miao, Wenjing Lu, Xiaojing Zhang, Zhimao Yang, Chuncai Kong
Summary: A ternary flower-like Cu2O-Cu-Au nanocomposite was designed as electrochemical material for glucose detection, showing high sensitivity and detection limit due to the compound and synergistic effect of Cu and Cu2O, as well as the unique structure and active substances. The CCAu electrode demonstrated comparable performance to a commercial analyzer in testing blood glucose concentration in human serum, indicating its great potential in practical electrochemical sensors.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yuanmeng Zhao, Yunhao Jiang, Yan Mo, Yueming Zhai, Juejing Liu, Andrew C. C. Strzelecki, Xiaofeng Guo, Changsheng Shan
Summary: It is critical to develop high-performance electrocatalysts for electrochemical nonenzymatic glucose sensing. In this work, a single-atom Pt supported on Cu@CuO core-shell nanowires (Pt-1/Cu@CuO NWs) for electrochemical nonenzymatic glucose sensor is designed. The Pt-1/Cu@CuO NWs exhibit outstanding electrocatalytic performance towards glucose, with lower onset potential and higher response current compared to Cu NWs. Sensors fabricated using Pt-1/Cu@CuO NWs also show high sensitivity, low detection limit, wide linear range, excellent selectivity, and great long-term stability. The work provides a new pathway for exploring highly active single-atom catalysts for electrochemical nonenzymatic glucose sensing.
Article
Chemistry, Multidisciplinary
Meijuan Yuan, Xiaotian Guo, Huan Pang
Summary: In this study, metallic Cu with a unique interconnected structure was prepared using Magnolia grandiflora leaves as the biomass reductant, and Cu/CuO, Cu/Cu2O, and CuS nanosheets were fabricated based on this structure. Electrochemical sensors were then made using the three derivations to study their sensing performance of glucose. The results showed that the nanosheets encapsulating the metallic Cu superstructure guarantee excellent conductivity and stability.
MATERIALS TODAY CHEMISTRY
(2021)
Article
Chemistry, Physical
Marzieh Shakiba, Maryam Afsharpour
Summary: In this work, a novel synthesis method of graphenic SiC nanotube (g-SiCNT) and its Cu-doped structure (Cu/g-SiCNT) was presented. A Cu/g-SiCNT/CuO nanocomposite was prepared for glucose oxidation, which showed better response compared to CuO nanoparticles and CNT/CuO electrodes. The nanocomposite exhibited linear response and excellent electrochemical glucose sensing properties with high sensitivity and detection limit. The synthesized sensor demonstrated good selectivity, reproducibility, and stability towards glucose, and was successfully applied in real blood plasma samples.
APPLIED SURFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Nadyah Alanazi, Tamil Selvi Gopal, Muthumareeswaran Muthuramamoorthy, Amani Ali E. Alobaidi, Reem Abdullah Alsaigh, Mohammed Hamad Aldosary, Saravanan Pandiaraj, Maram Almutairi, Andrews Nirmala Grace, Abdullah Alodhayb
Summary: Fine-tuning the morphology of nanostructures from 2D to 3D through structural engineering improves biosensing. In this study, a 3D ternary composite (MXene graphene aerogel-Cu2O composite) was synthesized by hydrothermal process and coprecipitation method. The composite exhibited a low crystallite size, spherical-shaped Cu2O, and a large surface area with a porous structure. A sensing electrode was fabricated and showed high sensitivities, wide linear ranges, low detection limit, and good stability, selectivity, and reproducibility. The 3D network of MXene and rGO nanosheets enhances charge transfer and promotes the sensing activity of nonenzymatic glucose sensors.
ACS APPLIED NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Zhaodi Ren, Rui Dong, Yuanan Liu
Summary: A free-standing Cu/Cu2O/CuO modified by graphene was prepared through thermal annealing and electrochemical exfoliation. The hybrid electrode exhibited high sensitivity, excellent anti-interference ability, good cycling stability, and time stability as a glucose sensor. This work provides a new approach to study the effects of graphene in improving the properties of metal oxides, particularly in glucose sensors.
Article
Engineering, Biomedical
Qie Fang, Hengjia Wang, Xiaoqian Wei, Yinjun Tang, Xin Luo, Weiqing Xu, Liuyong Hu, Wenling Gu, Chengzhou Zhu
Summary: Developing functional nanomaterials for nonenzymatic glucose electrochemical sensing platforms is important and challenging. Cu aerogels are synthesized as a model system for sensitive nonenzymatic glucose sensing. In situ electrochemical investigations and Raman characterizations reveal the catalytic mechanism of Cu-based nonenzymatic glucose sensing.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Environmental Sciences
Uthirakumar Periyayya, Devendiran Madhu, Kalaiarasan Subramaniyam, Hoki Son, In-Hwan Lee
Summary: A simple oxidation method was used to prepare CuO nanodisks on a flexible Cu sheet, with the crystal structure and surface morphology analyzed using various techniques. The in situ transformation of nanodisk surface after recycling accelerated dye degradation due to electron transfer. Efficient charge carrier separation was observed in the photodegradation system of Cu/CuO nanodisks, which was attributed to the generation of superoxide radical under daylight irradiation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Physical
P. Sagar, N. S. Arun Kumar, L. Shreenivasa, N. Srinivasa, Debasis De, R. T. Yogeeshwari, Ashoka Siddaramanna
Summary: A one-pot synthesis method has been developed to prepare CuO, binary Cu2O/CuO and Cu/Cu2O nanocomposites, and metallic Cu with different amounts of citric acid. The CuO synthesized with an oxidizer-to-fuel ratio of 1:0.5 and 1:1 shows excellent OER activity as compared to Cu2O/CuO, Cu/Cu2O, and pure metallic copper. The CuO derived from an oxidizer-to-fuel ratio of 1:1 exhibits a low overpotential and excellent stability over 25 hours.
Article
Nanoscience & Nanotechnology
Pattarachaya Preechakasedkit, Nithiwach Nawaukkaratharnant, Kanyapat Teekayupak, Atchara Lomae, Nipapan Ruecha
Summary: This paper presents a one-step nonenzymatic glucose sensor using a NaOH/PVA/PEO blend film and a rGO/Cu-Cu2O-modified electrode. The sensor allows direct measurements of real samples without sample preparation and pretreatment. The proposed sensor demonstrates good analytical performance and high storage stability.
JOURNAL OF SCIENCE-ADVANCED MATERIALS AND DEVICES
(2023)
Article
Nanoscience & Nanotechnology
ShaoZhen Wang, Mi Zheng, Xue Zhang, MingPeng Zhuo, Qingqing Zhou, Yang Su, Min Zheng, Guotao Yuan, ZuoShan Wang
Summary: In this study, flowerlike CuO/Au nanoparticles with 2D nanomaterial characteristics and excellent glucose sensing performance were prepared through microwave hydrothermal synthesis of sea urchinlike CuO followed by self-generated acid etching in the presence of HAuCl4 and NaBH4. The Au nanoparticles with an average size of 15 nm were uniformly distributed on the surface of CuO nanoflakes during the acid etching process. The green and economical authigenic acid etching method demonstrated controlled preparation of 2D nanomaterials with specific properties.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Physical
Amine Laradji, Ying-Bo Shui, Bedia Begum Karakocak, Lynn Evans, Paul Hamilton, Nathan Ravi
Article
Biochemistry & Molecular Biology
Hana Barosova, Bedia Begum Karakocak, Dedy Septiadi, Alke Petri-Fink, Vicki Stone, Barbara Rothen-Rutishauser
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Review
Toxicology
Irini M. Dijkhoff, Barbara Drasler, Bedia Begum Karakocak, Alke Petri-Fink, Giuseppe Valacchi, Marc Eeman, Barbara Rothen-Rutishauser
PARTICLE AND FIBRE TOXICOLOGY
(2020)
Article
Chemistry, Physical
Arthur Cresce, Nico Eidson, Marshall Schroeder, Lin Ma, Yakira Howarth, Chongyin Yang, Janet Ho, Robert Dillon, Michael Ding, Alexander Bassett, Joseph Stanzione, Robinson Tom, Thiagarajan Soundappan, Chunsheng Wang, Kang Xu
JOURNAL OF POWER SOURCES
(2020)
Article
Biotechnology & Applied Microbiology
Barbara Drasler, Bedia Begum Karakocak, Esma Bahar Tankus, Hana Barosova, Jun Abe, Mauro Sousa de Almeida, Alke Petri-Fink, Barbara Rothen-Rutishauser
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Nanoscience & Nanotechnology
Bedia Begum Karakocak, Amine Laradji, Tina Primeau, Mikhail Y. Berezin, Shunqiang Li, Nathan Ravi
Summary: This study demonstrates the use of hyaluronan-conjugated nitrogen-doped carbon quantum dots (HA-nCQDs) for imaging of tumor cells and potential as carriers for targeted drug delivery. By grafting hyaluronic acid onto nCQDs, targeted internalization by cancer cells was achieved. Results show that HA-nCQDs can be used for imaging CD44-specific tumors and hold promise for targeted drug delivery into CD44-rich cells.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Amine M. Laradji, Alexander Kolesnikov, Bedia B. Karakocak, Vladimir J. Kefalov, Nathan Ravi
Summary: The study synthesized hyaluronic acid-based nanogels for triggered release and delivery of therapeutics to the posterior segment of the eye via topical application. The nanogels released drugs in a reducing environment and efficiently delivered a model drug to the mouse retina's photoreceptors, resulting in a partial recovery of photoreceptor function.
Article
Toxicology
Hana Barosova, Kirsty Meldrum, Bedia Begum Karakocak, Sandor Balog, Shareen H. Doak, Alke Petri-Fink, Martin J. D. Clift, Barbara Rothen-Rutishauser
Summary: The study compared the response of A549 cells grown in submerged and air-liquid interface (ALI) conditions in different laboratories, finding high variability in results. By repeating the experiment and improving the protocol, it was shown that using detailed protocols, identical reagents, personnel training, and endpoint analysis are crucial for obtaining reproducible results in independent laboratories.
TOXICOLOGY IN VITRO
(2021)
Article
Environmental Sciences
Sivarasan Ganesan, Sadha Sivam, Mari Elancheziyan, Sellappan Senthilkumar, Sankar Ganesh Ramakrishan, Thiagarajan Soundappan, Vinoth Kumar Ponnusamy
Summary: Valorization of chicken feather waste into high-value nanomaterial for the development of cost-effective electrochemical environmental monitoring sensor with excellent detection performance towards hydroquinone and catechol, demonstrating good stability and reproducibility.
ENVIRONMENTAL POLLUTION
(2022)
Article
Polymer Science
Amine Laradji, Bedia B. Karakocak, Alexander Kolesnikov, Vladimir J. Kefalov, Nathan Ravi
Summary: The ocular immune privilege protects the eye from immune responses but hinders drug delivery to the back of the eye. Hyaluronic acid-coated gold nanoparticles show potential as drug delivery vehicles to the retina, with enhanced distribution in the posterior segment and no adverse effects on visual function in mice.
Article
Multidisciplinary Sciences
Tzu-Yu Pan, Wei-Chung Tsai, Chun-Hsiang Tan, Ching-Mei Cheng, Wei Chen, Thiagarajan Soundappan, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Chia-Fang Wu, Vinoth Kumar Ponnusamy, Ming-Tsang Wu
Summary: This study developed a fast microextraction technique coupled with HPLC-MS/MS to simultaneously quantify warfarin and four NOACs in human urine samples. The method showed excellent linearity, precision, detection limits, and relative recoveries, making it a reliable and rapid monitoring tool in clinical settings.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Engineering, Biomedical
Manuela Estermann, Ricardo Coelho, Francis Jacob, Yen-Lin Huang, Ching-Yeu Liang, Ana Bela Faia-Torres, Dedy Septiadi, Barbara Drasler, Bedia Begum Karakocak, Irini Magdelina Dijkhoff, Alke Petri-Fink, Viola Heinzelmann-Schwarz, Barbara Rothen-Rutishauser
Summary: Reliable and predictive experimental models are urgently needed for studying the metastatic mechanisms of ovarian cancer cells in the omentum. The lack of certain omental cell types that influence cancer cell metastasis hinders the application of current tissue models. This study introduces a 3D multi-cellular human omentum tissue model that mimics the metastatic processes of ovarian cancer cells and allows the study of their interaction with endothelial cells and the effects of chemotherapeutic drugs. This model may serve as a platform for future patient-specific investigations in personalized oncology.
Article
Nanoscience & Nanotechnology
Fabienne Schwab, Barbara Rothen-Rutishauser, Aline Scherz, Thierry Meyer, Bedia Beguem Karakocak, Alke Petri-Fink
Summary: Waste containing nanomaterials, known as nanowaste, is a global safety concern that requires specific environmentally sound waste management and regulation.
NATURE NANOTECHNOLOGY
(2023)
Meeting Abstract
Respiratory System
Bedia Begum Karakocak, Gowsinth Gunasingam, Silvia Angeloni, Adrian Auderset, Alke Petri-Fink, Barbara Rothen-Rutishauser
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY
(2021)
Meeting Abstract
Ophthalmology
Nathan Ravi, Bedia Begum Karakocak, Amine M. Laradji
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2020)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
