Article
Chemistry, Inorganic & Nuclear
Zhiwei Ma, Di Zhang, Jie Guo, Man Li, Tieliang Wang, Haiyan Yin, Hongqi Wang, Jihong Liu
Summary: A new highly sensitive fluorescence turn-on probe (HgP1) based on anthraquinone derivatives has been designed and developed for the detection of Hg2+. The probe shows high selectivity towards Hg2+ in solution over other analytes, with a detection limit of 8.2 nM, and has good biocompatibility for living cell imaging applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Kaiqi Liu, Luminita Marin, Xinjian Cheng
Summary: Fluorescent beta-cyclodextrin (beta-CD) based probes containing naphthalimide group were synthesized to specifically recognize Hg2+/Hg+ in aqueous systems. The probes exhibit enhanced fluorescence intensity when binding with Hg2+/Hg+, and the hydrophobic parts of the probes form special micelle-like structures due to complexation with Hg2+/Hg+. The probes have the potential for detecting Hg2+/Hg+ in aqueous solutions without the use of organic solvents.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Applied
Yabei Chen, Ke Li, Shensong Zhang, Pan Xu, Bo Song
Summary: In this paper, a cationic amphiphile named DPP-10 was designed, synthesized, and applied as a turn-on fluorescence probe for BSA detection and selective cell imaging. DPP-10 exhibited weak fluorescence emission in solution, but its emission was significantly enhanced when BSA was added. The probe showed a low limit of detection, good selectivity for BSA, high photostability, and immunity to ion disturbance.
Review
Chemistry, Inorganic & Nuclear
Xiaojing Nan, Yuchen Huyan, Hongjuan Li, Shiguo Sun, Yongqian Xu
Summary: Transition metal ions play crucial roles in medicine, life sciences, and environmental science, but some like mercury, copper, and iron ions pose serious health and environmental risks due to biomagnification. Monitoring metal ion levels in organisms and the environment is urgent, and reaction-based fluorescent probes offer higher sensitivity and selectivity than traditional methods. Research on these probes for Hg2+, Cu2+, and Fe2+/Fe2+ detection has advanced in the past decade, with potential for interdisciplinary development in the future.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Inorganic & Nuclear
Satyajit Mahata, Sandeep Kumar, Souradeep Dey, Biman B. Mandal, Vadivelu Manivannan
Summary: The probe L, with hydrazinecarbothioamide and 1,8-naphthalimide moieties, has been synthesized and evaluated for its selective and sensitive colorimetric and fluorescent recognition ability towards Hg2+ and Ag+ ions in methanol-HEPES buffer solution. The reversible interaction of L with Hg2+ ion has been monitored using Na(2)EDTA. The potential of probe L in tracking Hg2+ and Ag+ in living cells has been established through fluorescence cell imaging experiments.
INORGANICA CHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Viktor Merz, Julia Merz, Maximilian Kirchner, Julian Lenhart, Todd B. Marder, Anke Krueger
Summary: A chemosensor based on pyrene monomer fluorescence with triazole groups demonstrates high selectivity in detecting Cu2+, Pb2+, and Hg2+ in organic solvents over a wide range of concentrations, even in the presence of common ions. The sensor's strongly emissive fluorescence is quenched by metal ion complex formation, leading to the formation of agglomerates. Conventional linear correlations are not observed for all concentrations, leading to the need for non-linear fits in analysis.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Spectroscopy
Zongcheng Wang, Weikang Su, Huihuang Zheng, Shun Yang, Tingting Yang, Ting Han, Wubliker Dessie, Xingrui He, Yuren Jiang, Yuanqiang Hao
Summary: Fluorescence probe detection of selenocysteine (Sec) content in cells is important for identifying human related diseases. Two turn-on fluorescent probes, A4 and B4, were designed and synthesized for fast and sensitive detection of Sec. Both A4 and B4 show rapid turn-on response, high selectivity, and sensitivity towards Sec, making them applicable for fluorescence imaging of Sec in living cells. A4 has a larger Stokes shift, wider pH range, and lower detection limit compared to B4, due to its excited state intramolecular proton transfer (ESIPT) effect. These two probes can serve as effective tools for detecting Sec in biological systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Yu Teng, Hong Yang, Xiang Li, Yongcheng Wang, Dali Yin, Yulin Tian
Summary: A novel fluorescent strategy was designed using a nitrone-modified 1,8-naphthalimide as a bioorthogonal-activated turn-on probe based on strain-promoted alkyne-nitrone cycloaddition. The resulting fluorescent rearrangement products displayed significant fluorescence enhancement, large stokes shift, and high fluorescence quantum yield, and were successfully applied for protein labeling and live cell mitochondrial visualization.
CHINESE JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Applied
Xiazhen Bao, Kaili Ai, Xuehui Cao, Dongping Chen, Bo Zhou, Congde Huo
Summary: Bioactive small molecules HClO and SO2 are crucial for maintaining normal physiological function. A newly developed dual-site and dual-turn-on fluorescence probe PTBI can simultaneously monitor these molecules in mitochondria, with fast response and low detection limits, providing a powerful tool for studying their physiological and pathological roles.
Article
Chemistry, Applied
Jiahou Geng, Juan Zheng, Wenjun Bai, Hui Yang, Yang Lu, Ning Wang, Yufen Zhao, Jinhui Wang
Summary: A near-infrared fluorescence probe PTP was developed to visualize the distribution of nitroreductase (NTR) in tumor cells, demonstrating a fast response and excellent biocompatibility.
Article
Chemistry, Multidisciplinary
Yanxi Song, Mengjie Yan, Xiaofeng Xia, Zhixiu Pan, Jinjiang Shi, Hongqi Li, Peihong Cong
Summary: A fluorescent probe (probe C) based on coumarin-thiourea conjugate was developed for selective detection of Hg2+. Addition of Hg2+ to probe C induced obvious enhancement of the fluorescence intensity. Probe C exhibited good selectivity toward Hg2+ and good anti-interference performance over other common competitive metal ions.
Article
Optics
Jing Ying Yang, Jia Hong Han, Zhuo Bin Shang, Yu Wang, Shao Min Shuang
Summary: A new Schiff base probe, BPC, based on 4-Cyanobiphenyl, is reported for efficient fluorometric detection of hazardous Cd2+ ions through selective turn-on fluorescence responses. The 1:1 complex formation between BPC and Cd2+ enhances fluorescence signals, with a detection limit lower than WHO drinking water standard, making it applicable for Cd2+ sensing in neutral aqueous media.
JOURNAL OF LUMINESCENCE
(2022)
Article
Spectroscopy
Fei Han, Liang Liu
Summary: Fingerprints play an important role in identifying personal information. An amphiphilic probe HNP was designed for assisting the development (imaging) of latent fingerprints. The study discussed the photophysical parameters, LFPs imaging performance, and biosafety of HNP, showing efficient AIE effect in an aggregated state and successful retrieval of details down to Level 3.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yusuke Okamoto, Naoya Kishikawa, Masayori Hagimori, Mahmoud El-Maghrabey, Shigeru Kawakami, Naotaka Kuroda
Summary: Copper (II) is an important metal ion for the human body and disruption of its homeostasis can lead to neurological diseases. Most reported probes for Cu (II) determination are based on fluorescence quenching mechanism, which has low precision and reliability. In this study, a new turn-on fluorescence probe with high selectivity and sensitivity for Cu2+ detection has been developed and successfully applied for monitoring Cu2+ in tap water.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Physical
Zhigang Gao, Siyan Qiu, Minchuan Yan, Haibo Liu, Shaohui Lu, Huihui Lian, Peng Zhang, Jing Zhu, Mingjie Jin
Summary: Mercury ions are highly toxic, making the monitoring and quantification of mercury ions significant. A novel reaction-based fluorescence probe RANS was designed and synthesized for the detection of Hg2+. The probe exhibited rapid response, high sensitivity, and good selectivity. It could selectively image Hg2+ in living cells with low cytotoxicity and quantitatively detect Hg2+ in real water samples.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Materials Science, Biomaterials
Jiaxi Ru, Xiangquan Mi, Liping Guan, Xiaoliang Tang, Zhenghua Ju, Guolin Zhang, Chunming Wang, Weisheng Liu
JOURNAL OF MATERIALS CHEMISTRY B
(2015)
Article
Chemistry, Analytical
Qingxin Han, Zuolin Mou, Haihong Wang, Xiaoliang Tang, Zhe Dong, Li Wang, Xue Dong, Weisheng Liu
ANALYTICAL CHEMISTRY
(2016)
Article
Chemistry, Multidisciplinary
Wanmin Chen, Xiaoliang Tang, Wei Dou, Zhenghua Ju, Benhua Xu, Wenxuan Xu, Weisheng Liu
CHEMICAL COMMUNICATIONS
(2016)
Article
Chemistry, Inorganic & Nuclear
Benhua Xu, Xiaoliang Tang, Ji'an Zhou, Wanmin Chen, Haile Liu, Zhenghua Ju, Weisheng Liu
DALTON TRANSACTIONS
(2016)
Article
Chemistry, Analytical
Yaming Liu, Jinyu Zhang, Jiaxi Ru, Xiang Yao, Yang Yang, Xinghua Li, Xiaoliang Tang, Guolin Zhang, Weisheng Liu
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Article
Chemistry, Analytical
Min Deng, Chengduan Yang, Deyan Gong, Anam Iqbal, Xiaoliang Tang, Weisheng Liu, Wenwu Qin
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Article
Chemistry, Analytical
Chengduan Yang, Deyan Gong, Xudong Wang, Anam Iqbal, Min Deng, Yali Guo, Xiaoliang Tang, Weisheng Liu, Wenwu Qin
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Article
Chemistry, Analytical
Yang Yang, Yan Feng, Ying-Zhe Wang, Fang-Zhou Qiu, Xiao-Liang Tang, Guo-Lin Zhang, Wei-Sheng Liu
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Article
Materials Science, Biomaterials
Qingxin Han, Zhe Dong, Xiaoliang Tang, Li Wang, Zhenghua Ju, Weisheng Liu
JOURNAL OF MATERIALS CHEMISTRY B
(2017)
Article
Materials Science, Biomaterials
Weifang Luo, Huie Jiang, Xiaoliang Tang, Weisheng Liu
JOURNAL OF MATERIALS CHEMISTRY B
(2017)
Article
Chemistry, Analytical
Huie Jiang, Yan Liu, Weifang Luo, Yujiao Wang, Xiaoliang Tang, Wei Dou, Yumei Cui, Weisheng Liu
ANALYTICA CHIMICA ACTA
(2018)
Article
Chemistry, Multidisciplinary
Li Wang, Cong Xu, Qingxin Han, Xiaoliang Tang, Panpan Zhou, Ruilian Zhang, Guoshu Gao, Benhua Xu, Wenwu Qin, Weisheng Liu
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Analytical
Yang Yang, Fangzhou Qiu, Yingzhe Wang, Yan Feng, Xuerui Song, Xiaoliang Tang, Guolin Zhang, Weisheng Liu
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Multidisciplinary
Wanmin Chen, Xiaoliang Tang, Wei Dou, Bei Wang, Lirong Guo, Zhenghua Ju, Weisheng Liu
CHEMISTRY-A EUROPEAN JOURNAL
(2017)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
