Article
Materials Science, Multidisciplinary
Jisu Hong, Yonghwan Kwon, Min Sang Kwon, Chaenyung Cha
Summary: This paper presents a brush copolymer, P(AzPEG), as a multifunctional polymeric cross-linker for carboxylate-containing acrylic adhesives. The density and length of the AzPEG brush can be conveniently controlled to effectively regulate the mechanical and adhesive properties of the adhesive without significant changes in concentration.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Justas Svirelis, John Andersson, Anna Stradner, Andreas Dahlin
Summary: This study presents a physical model to determine the contribution of bulk response from molecules in solution and verifies its accuracy. By properly subtracting the bulk response, an interaction between poly(ethylene glycol) brushes and the protein lysozyme is revealed, and the inaccuracy of the bulk response correction method implemented in commercial instruments is shown. Furthermore, the bulk response correction also reveals the dynamics of self-interactions between lysozyme molecules on surfaces.
Article
Polymer Science
Lukas P. Sadowski, Andrew Singh, Daniel H. Luo, Michael J. Majcher, Ivan Urosev, Meghan Rothenbroker, Vitaliy Kapishon, Niels M. B. Smeets, Todd Hoare
Summary: In this study, brush co-polymer analogues were synthesized via atom transfer radical polymerization (ATRP) and used to fabricate nanoparticles for drug delivery applications. These analogues exhibited high colloidal stability, favorable in vitro cytocompatibility, and effective drug loading. The functionalization of the hydrophobic block allowed for controlled release of the nanoparticles.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Physical
Tanja Traini, Duccio Tatini, Elisa Rossi, Gianluca Ciancaleoni, Pierandrea Lo Nostro
Summary: By investigating the molecular structure and adsorption capacity of a low temperature transition mixture (LTTM), the properties of the absorbing material can be optimized for the development of reusable carbon capture systems. The LTTM, composed of ethylene glycol, potassium hydroxide, and boric acid (3:1:1), can effectively absorb CO2 at room temperature and release it through boric acid catalysis.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Biomedical
Hongsuh Choi, Anna Schulte, Mareike Mueller, Mineon Park, Suenghwan Jo, Holger Schoenherr
Summary: Despite decades of biomedical advances, the colonization of implant devices with bacterial biofilms remains a major cause of implant failure. New strategies and materials, such as polymer coatings with triggered antibiotic release, are needed to suppress bacterial colonization at both early and later stages. The use of thermally responsive polymer coatings on titanium implants showed controlled and thermally triggered release of antibiotics, providing enhanced bactericidal effects in initial in vivo tests.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Chemistry, Physical
Kewang Zhang, Cheng Wang, Siyu Guo, Shujin Li, Zhengying Wu, Shinichi Hata, Jie Li, Yukihide Shiraishi, Yukou Du
Summary: This study successfully prepared trimetallic PdAgCu nanospheres with abundant surface bulges for ethylene glycol oxidation reaction and compared them with bimetallic PdAg nanospheres to investigate the performance enhancement mechanism. The optimized PdAgCu nanospheres exhibited superb mass activity and electrochemical stability. The incorporation of Cu into PdAg nanospheres further enhanced the photoelectrocatalytic performance and increased noble metal atom utilization.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Environmental
Kewang Zhang, Cheng Wang, Huaming You, Bin Zou, Siyu Guo, Shujin Li, Yukou Du
Summary: Coupling the unique surface plasmon resonance (SPR) of plasma metals with electrocatalysis can enhance the efficiency of alcohol oxidation reactions. This study demonstrates the commendable SPR effect of copper in boosting the electrocatalytic efficiency of PdCu nanosheets under visible light illumination, providing new avenues for developing novel and high-efficiency photoelectrocatalysts.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Di Zhang, Chaoyang Zhang, Hongxu Gao, Jing Sui, Ning Sui, Lina Wang, Manhong Liu, William W. Yu
Summary: PdFe nanosheets (NSs) were synthesized through a hydrothermal method and efficiently catalyzed ethylene glycol electrooxidation reaction (EGOR), with a significantly increased mass activity under light irradiation. The high activity is mainly attributed to the high photothermal conversion efficiency and the exposure of high energy facet.
Article
Chemistry, Physical
Sahadev Barik, Amita Mahapatra, Naupada Preeyanka, Moloy Sarkar
Summary: This study investigates the structure and conformational dynamics of proteins in the presence of two deep eutectic solvents (DESs). The results demonstrate that the composition of DESs plays a crucial role in governing the overall stability and conformational dynamics of proteins.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Physics, Applied
Md Ashiqur Rahman, Yohei Yomogida, Mai Nagano, Ryoga Tanaka, Kazuhiro Yanagi
Summary: Using the dispersant PEG, W18O49 nanowire samples with relatively small diameters were successfully prepared, with bundles mainly containing an average diameter of less than 10 nm.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2022)
Article
Chemistry, Analytical
Luca Burratti, Michele Sisani, Irene Di Guida, Fabio De Matteis, Roberto Francini, Paolo Prosposito
Summary: This study describes an innovative approach to integrate silver nanoparticles (AgNPs) into poly(ethylene glycol) diacrylate (PEGDA) hydrogels. The composite material can detect and eliminate Hg(II) ions from water. The sensing properties of Hg(II) and removal efficiency were investigated, showing linear dependence and enhanced removal efficiency of the doped material. The interaction between Hg(II) ions and the modified hydrogel adhered to the Langmuir isotherm model, suggesting chemisorption as the driving mechanism.
Article
Physics, Nuclear
O. P. Artykulnyi, M. M. Avdeev, Ye M. Kosiachkin, V. Petrenko, I Safarik, L. A. Bulavin
Summary: In this study, a neutral polymer poly(ethylene glycol) with a molecular weight of Mw = 20 kDa was investigated on silicon substrates in an aqueous medium using specular neutron reflectometry. The structural changes in the density profile of the polymer brush caused by interactions with micelles of anionic surfactant were observed. The formation of molecular polymer-micelle associates in the bulk of the solution was found to be related to the observed effect.
NUCLEAR PHYSICS AND ATOMIC ENERGY
(2021)
Review
Chemistry, Multidisciplinary
Andreas Frutiger, Alexander Tanno, Stephanie Hwu, Raphael F. Tiefenauer, Janos Voros, Nako Nakatsuka
Summary: The differentiation between specific and nonspecific binding in molecular interactions has been achieved in nature through precise control of biomolecules. However, artificial biosensors have struggled to overcome this issue. Through theoretical models and classification frameworks, it is possible to gain a better understanding and optimize the performance of biosensors, while exploring ways to address the challenge of nonspecific binding.
Article
Biochemical Research Methods
Shokoofeh Maghari, Erik Reimhult, Parviz Ghezellou, Alireza Ghassempour
Summary: The present study evaluated the influence of surface properties of nanoparticles (NPs) on the intensity of mass signals in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and laser desorption/ionization mass spectrometry (LDI-MS) experiments. The results indicated that the surface ligands of NPs significantly enhanced the signal intensity based on electrostatic interaction and laser energy absorption in LDI-MS analyses. In MALDI-MS experiments, achieving colloidal stability of NPs in the matrix solution led to a significant signal improvement.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2022)
Article
Instruments & Instrumentation
Tayebeh Saghaei, Erik Reimhult, Peter D. J. van Oostrum
Summary: We present a technique for rapidly changing the contents of a small sample chamber with minimal sample consumption. Our design eliminates dead volume and minimizes mixing, making it an exciting alternative to traditional solutions. It also functions as an efficient bubble trap.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2022)
Article
Food Science & Technology
R. R. Birke, T. Causon, R. Turetschek, F. Emerstorfer, T. Karner, K. J. Domig, S. Hann
Summary: The quantification of nitrate and nitrite in molasses is an emerging requirement for the sugar industry. Establishing a validated analytical methodology is necessary for compliance with EU-guidelines. The study shows that quantification of nitrate and nitrite in molasses can be achieved with excellent precision under repeatability conditions.
Article
Microbiology
Lucija Podrzaj, Johanna Burtscher, Konrad J. Domig
Summary: This study investigated the genetic diversity and functional traits of C. tyrobutyricum strains related to late blowing defects in cheese. Comparative genomics analysis revealed a high level of genetic diversity and identified key genes related to translation, energy production, and defense mechanisms. The findings provide important insights into the spoilage potential of C. tyrobutyricum in cheese.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Raju Koorakula, Matteo Schiavinato, Mahdi Ghanbari, Gertrude Wegl, Nikolaus Grabner, Andreas Koestelbauer, Viviana Klose, Juliane C. Dohm, Konrad J. Domig
Summary: The emergence of resistance against common antibiotics in the gut microbiota is a major issue. Phytogenic feed additives (PFAs) have the potential to improve animal health by positively affecting the gut microbial ecosystem. This study found that PFAs can decrease the abundance of antibiotic resistance genes and could be an alternative to antibiotics in poultry farming.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Florian Hemetsberger, Benjamin Zwirzitz, Nadia Yacoubi, Wolfgang Kneifel, Karl Schedle, Konrad J. Domig
Summary: The study investigates the impact of heat treatment and soybean variety on the gut microbiota of chickens. The results show that both factors affect the abundance of certain bacterial species in the chicken's gut, highlighting the sensitivity of the microbial community to dietary differences.
Article
Veterinary Sciences
Luca Porfiri, Johanna Burtscher, Richard T. Kangethe, Doris Verhovsek, Giovanni Cattoli, Konrad J. Domig, Viskam Wijewardana
Summary: This study evaluated the effects of gamma irradiation and heat inactivation on different strains of lactic acid bacteria (LAB) and their ability to preserve metabolic activity and immune modulation. The results showed that gamma irradiation could retain metabolic activity and immune modulation, while heat inactivation could not. Different strains of LAB and inactivation methods had varying impacts on immune modulation, highlighting the potential of gamma irradiation in producing safe non-replicative metabolically active LAB and its application as a vaccine adjuvant.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agronomy
Yvonne Kummer, Christian Fikar, Johanna Burtscher, Martina Strobl, Reinhard Fuchs, Konrad J. Domig, Patrick Hirsch
Summary: This study aimed to simulate the impact of an African swine fever outbreak in Austria and evaluated control strategies and identified bottlenecks. A hybrid approach of discrete-event and agent-based simulation was used. The results compared two control strategies and showed that with a preventive culling strategy, fewer farms would be infected and fewer pigs would be culled.
Article
Multidisciplinary Sciences
Raju Koorakula, Mahdi Ghanbari, Matteo Schiavinato, Gertrude Wegl, Juliane C. Dohm, Konrad J. Domig
Summary: This study aimed to determine the impact of different sample storage and RNA extraction strategies on the recovery and integrity of microbial RNA extracted from livestock fecal samples. Differences in the extraction method and sample type (pig or chicken) significantly affected the quantity and quality of RNA. Storing the fecal samples in RNALater and using the PM kit for extraction yielded the best results in terms of RNA yield and integrity.
Review
Food Science & Technology
Nicola Pacher, Johanna Burtscher, Sophia Johler, Danai Etter, Denisse Bender, Lars Fieseler, Konrad J. Domig
Summary: As the spoilage of bread threatens global food security, this review provides an overview of the routes of entry of Bacillus endospores into bread, the bacterial species implicated in rope spoilage, the factors influencing rope development, and the methods used to assess bacterial rope-forming potential. However, there are still key knowledge gaps and challenges that need to be addressed in future research.
Article
Nanoscience & Nanotechnology
Katharina Schmidt, Simone Hageneder, Bernadette Lechner, Barbara Zbiral, Stefan Fossati, Yasaman Ahmadi, Maria Minunni, Jose Luis Toca-Herrera, Erik Reimhult, Ivan Barisic, Jakub Dostalek
Summary: This study tailored rolling circle amplification (RCA) for affinity biosensors relying on optical probing with confined surface plasmon field. By combining surface plasmon resonance (SPR) and surface plasmon-enhanced fluorescence (PEF) methods, the impact of long RCA-generated single-stranded DNA (ssDNA) chains on sensor response enhancement was investigated. The reported RCA implementation improved the limit of detection (LOD) for model target analyte, showing enhancement in sensor response and potential for single-molecule detection.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Microbiology
Botond Bendeguz Suranyi, Benjamin Zwirzitz, Csilla Mohacsi-Farkas, Tekla Engelhardt, Konrad J. Domig
Summary: In order to enhance agricultural productivity and feed the growing population, irrigation is crucial. However, the use of poorly characterized water sources increases the prevalence of foodborne diseases. Therefore, analyzing microorganisms in irrigation water can help prevent such cases.
Article
Biochemistry & Molecular Biology
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Platt, Erik Reimhult
Summary: Core-shell superparamagnetic iron oxide nanoparticles have great potential as a therapeutic and diagnostic platform in biological systems. This study investigates the biological effects of multifunctional cyclodextrin-appended SPIONs (CySPION) in mutant Npc1-deficient CHO cells. The results show that CySPIONs have low cytotoxicity, are strongly endocytosed, and localized in the lysosomal compartment. The pH-sensitive chemistry of these nanoparticles allows for the release of monomeric cyclodextrins, promoting the removal of accumulated cholesterol. Additionally, CySPIONs demonstrate high transport across blood-brain barrier models, suggesting their potential as a therapeutic approach for cholesterol-related brain diseases.
Article
Food Science & Technology
Sophie Hillinger, Julia Saeckler, Konrad J. Domig, Stefanie Dobrovolny, Rupert Hochegger
Summary: Insects could potentially become a reliable food source for humans in the future and help solve issues with the current food chain. A new DNA metabarcoding method that targets a specific mitochondrial DNA fragment was developed to identify and differentiate insects in food. The method was successfully able to correctly identify insect species in various samples.
Article
Microbiology
Guruprakash Subbiahdoss, Sarah Osmen, Erik Reimhult
Summary: The Komagataeibacter bacteria in kombucha can produce cellulosic biofilms using hydrocarbons as the sole source of carbon and energy. The presence of biosurfactants in kombucha leads to a faster decrease in interfacial tension and the formation of stable and elastic biofilm membranes.
