Journal
SEMINARS IN DIAGNOSTIC PATHOLOGY
Volume 35, Issue 2, Pages 143-152Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semdp.2017.11.012
Keywords
Adenocarcinoma; Arginase; CDX2; CK7; CK20; GATA3; HPV; Napsin; Neuroendocrine; P63; PAX8; PSA; PSAP Squamous Cell Carcinoma; TIT1; Uroplakin; WT1
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Pathologists use immunohistochemistry is their day-to-day practices to assist in distinguishing site of origin of metastatic carcinomas. Here, the work-up is discussed neuroendocrine carcinomas, squamous cell carcinomas and adenocarcinomas with particular attention to tumor incident rates and predictive values of the best-performing immunohistochemical markers.
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