Article
Biophysics
Nadia Najafabadipour, Somayeh Mojtabavi, Hossein Jafari-Nodoushan, Nasrin Samadi, Mohammad Ali Faramarzi
Summary: The study utilized osmolytes-stabilized laccase to remove levofloxacin in urea-containing solution, with sorbitol and proline identified as the most efficient laccase protectants. The presence of these osmolytes significantly improved the enzyme activity and bio-removal efficiency of levofloxacin. Additionally, spectroscopic analysis revealed different biotransformation products of levofloxacin, indicating various reaction pathways such as demethylation and hydroxylation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Dermatology
Jinjing Jia, Xiumei Mo, Fenggen Yan, Junfeng Liu, Siqi Ye, Yu Zhang, Ying Lin, Hongyi Li, Dacan Chen
Summary: The study found varying levels of Th1/Th2/Th17/Treg imbalance in patients with atopic dermatitis. YAP was downregulated in Treg cells and upregulated in Th17 cells, while it was downregulated in the AD epidermis. Changes in YAP expression may lead to T cell imbalance and hinder epidermal healing in AD.
JOURNAL OF DERMATOLOGICAL SCIENCE
(2021)
Article
Cell Biology
Longxiu Yang, Yuan Qin, Chongdong Jian
Summary: This study developed a classifier using RNA expression data to accurately distinguish AD patients and healthy individuals, and identified 3 core genes that may be related to the pathogenesis of AD. Analysis revealed that these core genes played a pivotal role in determining AD.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Xiangjia Zhu, Jiaqi Meng, Chaofeng Han, Qingfeng Wu, Yu Du, Jiao Qi, Ling Wei, Hao Li, Wenwen He, Keke Zhang, Yi Lu
Summary: This study reveals that highly myopic patients exhibit higher anxiety levels and elevated levels of CC chemokine ligand 2 (CCL2) and monocytes in the blood. Using mouse models and various experimental methods, the researchers found that high myopia increases infiltration of monocytes/macrophages into the eyes and brains, leading to disruption of the blood-ocular barrier and blood-brain barrier. However, highly myopic mice deficient in Ccl2 show reduced infiltration and barrier disruption, as well as less anxiety. Furthermore, administration of CCL2-neutralizing antibodies provides significant relief from high myopia-related anxiety.
Article
Agronomy
Min Zhou, Xinyu Zhang, Biying Pan, Jiaqi Zhu, Xiaoxiao Qian, Xian Li, Kangkang Xu, Bin Tang, Can Li
Summary: High concentrations of carbon dioxide can effectively control most storage pests. However, excessively high concentrations of carbon dioxide can have negative effects on the biochemical and physiological characteristics of Tribolium castaneum.
Review
Medicine, General & Internal
Masaru Honma, Hiroyoshi Nozaki
Summary: Psoriasis is a chronic inflammatory skin disease with bothersome symptoms, but recent advances in molecular-targeted therapies have shown promising clinical effects in treating severe symptoms and related skin diseases. Biomarkers such as cytokines, chemokines play a crucial role in defining therapeutic strategies, and blood protein markers show great potential in daily clinical practice.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biotechnology & Applied Microbiology
Junjie Wang, Zeyu Li, Fenfen Yin, Rui Zhang, Ying Zhang, Zhengxin Wang, Xiumei Sheng
Summary: GLIPR1 plays a dual role in cancer, acting as an oncoprotein in some types such as gliomas and breast cancers, while functioning as a tumor suppressor in others like prostate cancers and lung cancers. The mechanisms of GLIPR1 in different tumors remain unclear, but it shows potential in cancer treatment through gene therapy and protein therapy.
CANCER GENE THERAPY
(2022)
Article
Agronomy
Maria Vazquez-Hernandez, Irene Romero, Maria Teresa Sanchez-Ballesta, Carmen Merodio, Maria Isabel Escribano
Summary: Plant cells respond to environmental stressors through the increase of stress-related proteins and osmotically active compounds. In table grape postharvest storage, a second 3-day 20 kPa CO2 treatment reduces the occurrence of cold storage disorders by counteracting cell damage and oxidative stress. The study focuses on how this treatment modulates stress defense strategies and the expression of protective compounds in table grapes.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Xin He, Xinyu Gao, Weidong Xie
Summary: This article reviews the interaction between skin metabolism and aging, covering glucose, protein, and lipid metabolism, and explores relevant strategies for regulating skin metabolism. It is found that skin aging affects the metabolism of glucose, protein, and lipids, and the metabolism of these substances also affects the process of skin aging. Regulating specific metabolic disorders in the skin is an important anti-aging strategy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Entomology
Zi-Qi Wu, Li-Wen Guan, Bi-Ying Pan, Hai-Tian Xu, Yu-Jia Luo, Min Zhou, Jia-Yong Zhang, Shi-Gui Wang, Can Li, Bin Tang
Summary: This study found that silencing the HIF1-alpha gene in the Tribolium castaneum insect under low oxygen conditions resulted in decreased ATP and NAD+ levels, increased soluble trehalase activity, and enhanced expression of genes related to trehalose metabolism and insulin metabolic pathway. These findings highlight the important role of the HIF1-alpha gene in regulating metabolism in T. castaneum.
JOURNAL OF STORED PRODUCTS RESEARCH
(2022)
Review
Cell Biology
Xue Zhou, Youdong Chen, Lian Cui, Yuling Shi, Chunyuan Guo
Summary: This article reviews the crucial role of keratinocytes in the pathogenesis of psoriasis, emphasizing the significance of targeting keratinocytes for the treatment of psoriasis.
CELL DEATH & DISEASE
(2022)
Review
Health Care Sciences & Services
Jinjing Jia, Yuqian Wang, Xiumei Mo, Dacan Chen
Summary: Psoriasis and skin tumors are chronic diseases with limited understanding of their causes and treatment options. YAP, a member of the Hippo signaling pathway, plays an important role in these diseases by regulating cell apoptosis, proliferation, and differentiation, as well as maintaining the skin structure. Recent studies have shown increased expression of YAP in psoriasis and skin tumors, indicating its potential role in disease pathogenesis. Research on new drugs targeting YAP may provide novel approaches for the treatment of skin diseases.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Jun Tanaka, Tomoya Takashima, Naojiro Abe, Tamo Fukamizo, Tomoyuki Numata, Takayuki Ohnuma
Summary: Two rice GH18 chitinases, Oschib1 and Oschib2, belonging to family 8 of PR proteins, were expressed, purified, and characterized. Oschib1 and Oschib2 preferentially cleaved the second glycosidic linkage from the non-reducing end of substrate chitin oligosaccharides. They inhibited the growth of Fusarium solani but had weak or no antifungal activity against Aspergillus niger and Trichoderma viride.
Article
Plant Sciences
Peng Zhang, Xiaoding Ma, Lina Liu, Chanjuan Mao, Yongkang Hu, Bingxiao Yan, Jia Guo, Xinyu Liu, Jinxia Shi, Gang-Seob Lee, Xiaowu Pan, Yiwen Deng, Zhengguang Zhang, Zhensheng Kang, Yongli Qiao
Summary: In this study, a lesion mimic mutant (LMM) called spl38 was identified in rice, which is essential for plant defense and cell death. The spl38 mutant showed enhanced resistance to rice pathogens and delayed flowering, while overexpression of OsMED16 increased susceptibility. OsMED16 interacts with OsPR3 to negatively regulate cell death and immunity in rice, possibly through the chitin signaling pathway.
Article
Plant Sciences
Hiroshi Fukayama, Fumihiro Miyagawa, Naoki Shibatani, Aiko Koudou, Daisuke Sasayama, Tomoko Hatanaka, Tetsushi Azuma, Yasuo Yamauchi, Daisuke Matsuoka, Ryutaro Morita
Summary: CO2-responsive CCT protein (CRCT) functions as a positive regulator of starch synthesis-related genes, specifically in the leaf sheath of rice. It binds to the promoter regions of these genes, forms complexes in vivo, and interacts with 14-3-3-like proteins to control the expression of key starch synthesis-related genes, despite differences in expression sites.
PLANT CELL AND ENVIRONMENT
(2021)
Article
Plant Sciences
Maria Vazquez-Hernandez, Irene Romero, Maria Teresa Sanchez-Ballesta, Carmen Merodio, Maria Isabel Escribano
Summary: This study analyzed the in silico sequencing and in vitro functional characteristics of two dehydrin isoforms, revealing differences in structure and function between VviDHN2 and VviDHN4. While both showed slight antifungal activity, VviDHN4 demonstrated multifunctionality as a molecular shield, chaperone, reactive oxygen species scavenger, and antifreeze agent. These findings emphasize the importance of specific amino acid composition and posttranslational modifications in modulating dehydrin biological function.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Plant Sciences
Silvia Medda, Maria Teresa Sanchez-Ballesta, Irene Romero, Leonarda Dessena, Maurizio Mulas
Summary: For the myrtle species, different genotypes produce dark-blue or white berries depending on peel color, with dark-blue cultivars showing increased anthocyanin content and specific flavonoid gene expression compared to white cultivars. The transcript levels of UFGT in dark-blue cultivars corresponded with anthocyanin accumulation, while gene expression for flavonols and flavan-3-ols were modulated differently during ripening.
Article
Plant Sciences
Sabrine Hdira, Loua Haddoudi, Mohsen Hanana, Irene Romero, Asma Mahjoub, Hatem Ben Jouira, Ndiko Ludidi, Maria Teresa Sanchez-Ballesta, Chedly Abdelly, Mounawer Badri
Summary: Results showed that TN1.11 exhibited higher salt tolerance compared to the other lines, while TN6.18 was the most susceptible to salinity. Functional characterization of the MtERF1 gene revealed its expression mainly in roots and inducibility by NaCl and low temperature, with a greater increase in expression under salt stress in the salt-tolerant line TN1.11.
Article
Biochemistry & Molecular Biology
Irene Romero, Maria Vazquez-Hernandez, Manuel Tornel, M. Isabel Escribano, Carmen Merodio, M. Teresa Sanchez-Ballesta
Summary: The study found that ethanol vapor can reduce decay incidence, weight loss, and rachis browning index of It 681-30 grapes stored at low temperature and during the shelf-life period at 20 degrees C, and also modulate the expression of different genes. Additionally, the expression of aquaporin transcripts was activated in samples with higher weight loss.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agriculture, Multidisciplinary
Irene Romero, M. Isabel Escribano, Carmen Merodio, M. Teresa Sanchez-Ballesta
Summary: This article discusses the application of short-term high-CO2 treatments and multi-omics approach to maintain the postharvest quality of soft fruits. It also highlights the importance of high-throughput transcriptomic technologies in understanding the mechanisms modulated by short-term gaseous treatments.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Irene Romero, Raquel Rosales, M. Isabel Escribano, Carmen Merodio, M. Teresa Sanchez-Ballesta
Summary: Short-term gaseous treatments can improve rachis quality during table grape postharvest by reducing oxidative stress and cell wall degradation. This improvement is achieved through the modulation of the non-enzymatic and enzymatic antioxidant systems, as well as the expression of ethylene and ABA regulatory genes. This study provides new insights into the mechanisms underlying the beneficial effects of gaseous treatments on rachis browning.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Ivan del Olmo, Irene Romero, Maria Dolores Alvarez, Rosa Tarradas, Maria Teresa Sanchez-Ballesta, Maria Isabel Escribano, Carmen Merodio
Summary: This study analyzed the transcriptomic changes of wild strawberries under different storage conditions using RNA-seq and identified key genes related to cell wall integrity, softening, and oxidative stress. High CO2 treatment increased firmness and maintained cell turgor, while air-cold storage and non-cold storage at ambient temperature led to gene transcription changes associated with softening and cell wall disassembly in strawberries.
FRONTIERS IN PLANT SCIENCE
(2022)
Editorial Material
Plant Sciences
Maria Teresa Sanchez-Ballesta, Itay Maoz, Carlos R. Figueroa
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Horticulture
Peng Jia, Rui Yan, Yuan Wang, Feng-huan Gao, Yang Liu, Qing-long Dong, Hao-an Luan, Xue-mei Zhang, Han Li, Su-ping Guo, Guo-hui Qi
Summary: The KNOX gene plays crucial roles in plant development, and this study identified 19 KNOX gene members in kiwifruit. One of the genes, AcKNOX11, is selectively expressed in flower buds and shoots, and its expression can be induced by ABA and melatonin. Functional analysis revealed that AcKNOX11 delays flowering, reduces plant height, alters leaf shape, and inhibits seed germination through ABA-melatonin interaction.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Dan Hua, Wen-Shu Chen, Rong-Yu Rao, Xu-Feng Chen, Huan-Huan Chen, Ning-Wei Lai, Lin-Tong Yang, Xin Ye, Li -Song Chen
Summary: This study revealed that nitrogen deficiency can lead to increased production of reactive oxygen species (ROS) and methylglyoxal (MG), but also enhances the ability of leaves and roots to detoxify these molecules. The effects of nitrogen deficiency on ROS and MG generation and their detoxification systems were found to be different in leaves and roots, with roots being more affected.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Shenghan Yang, Chonlong Chio, Wensheng Qin, Yanxi Pei, Guangpeng Pei, Yuen Zhu, Hua Li
Summary: This study evaluates the immobilization and deactivation of pathogen-produced enzymes and toxic metabolites by biochar in tomato Fusarium wilt and finds that biochar can effectively prevent disease occurrence.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Deborah Pagliaccia, Michelle Ortiz, Michael Rodriguez, Sophia Abbott, Agustina De Francesco, Madison Amador, Valeria Lavagi, Benjamin Maki, Francesca Hopkins, Jonathan Kaplan, Samantha Ying, Georgios Vidalakis
Summary: This study investigates the effectiveness of organic soil amendments (bokashi, biochar, and their combination) in promoting soil health, nutrient availability, and plant growth. The results show that these amendments can significantly alter soil parameters and have positive effects on soil and plant health.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Yu-Jeong Kwon, Min Jeong Hong, Minkyu Park, Dawon Jeon, Gah-Hyun Lim, Sungyul Chang, Dong-Hwan Kim, Jin-Baek Kim, Jundae Lee, Yeong Deuk Jo
Summary: Flowing LOCUS T (FT)-like genes play crucial roles in flowering induction in plants. Pepper FT-like genes are mostly expressed in leaves and interact with FLOWERING LOCUS D, promoting or delaying flowering. The unique evolutionary process of pepper FT-like genes provides insights for improving productivity.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Ziwen Su, Juan Yan, Binbin Zhang, Meng Sun, Zhixiang Cai, Zhijun Shen, Ruijuan Ma, Mingliang Yu
Summary: Bagging is a crucial cultivation measure that affects the quality of peach fruit by regulating exposure to light. This study investigated the effects of bagging on the content of phenolic compounds in peach fruit and identified the most sensitive compounds to bagging treatment. The study also explored the regulatory role of bagging on phenolic synthetic-related genes. The results showed that bagging affected the accumulation of different phenolics in different peach cultivars and light intensity played a significant role in the accumulation of anthocyanins and other phenolic substances in peach fruit. Additionally, the expression of structural genes and transcription factors related to phenolic synthesis was regulated by bagging and light conditions. These findings provide a foundation for understanding the regulation mechanism of light on the synthesis of phenolic compounds in peach fruit.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Yanfang Zhang, Xinzhi Cui, Zhilei Du, Xiulian Li, Bangdi Liu, Meng Liu, Xiangquan Zeng, Fengjun Guo, Xinguang Fan, Shuyang Sun
Summary: In this study, melatonin treatment effectively improved the aroma quality of apricots during low temperature storage by maintaining firmness and soluble solids content, inhibiting ethylene production, and regulating enzyme activities related to aroma synthesis.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Sang-Mo Kang, Shifa Shaffique, Md. Injamum-Ul-Hoque, Sarah Owdah Alomrani, Yong-Sung Park, In-Jung Lee
Summary: Salinity is a global environmental problem that affects the physiology and morphology of plants. Melatonin has been found to improve photosynthesis, antioxidant activities, and seedling characteristics in milk thistle plants exposed to salinity stress, thereby enhancing their salt tolerance.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Nadia Borgini, Haifa Benmoussa, Mohamed Ghrab, Mehdi Ben Mimoun
Summary: This study investigates the agroclimatic requirements of Prunus species cultivars growing in warm areas using Partial Least Squares regression. The findings reveal that the chilling and heat requirements of the cultivars appear discontinuous, with overlaps or transition periods between the two phases. The warm mean temperatures occurring during the chilling period are the main determinant of the flowering of the studied cultivars.
SCIENTIA HORTICULTURAE
(2024)
Review
Horticulture
Kayise Hypercia Maseko, Thierry Regnier, Belinda Meiring, Obiro Cuthbert Wokadala, Tonna Ashim Anyasi
Summary: Bananas are a significant tropical fruit with diverse cultivars, providing essential minerals, vitamins, and phytochemicals. The Cavendish group is preferred, but identifying suitable cultivars and maturity stages is crucial for various applications.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Godfrey Ouma, Joshua Wanyama, Isa Kabenge, Joseph Jjagwe, Mukulu Diana, John Muyonga
Summary: Irrigation plays a crucial role in increasing eggplant yields amidst climate change, but the deficit irrigation level for optimal growth remains uncertain. This study examined the effect of deficit drip irrigation on eggplant performance and found that irrigating at 75% field capacity maximizes yield and water saving in sandy clay loam soil.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Andrea Marcone, Giorgio Impollonia, Michele Croci, Henri Blandinieres, Stefano Amaducci
Summary: This study used Sentinel-2 satellite images to estimate biophysical and biochemical parameters of spinach crops and found that canopy-level parameters were estimated more accurately. The estimation of the canopy-scale parameter AGB using MCARI showed the highest accuracy, while the estimation of the leaf-scale parameter LCC using NDWI showed the lowest accuracy. At the field scale, the validation results for AGB estimation using SR were the best.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Chengsheng Gong, Guangjun Guo, Baogui Pan, Changzhou Gao, Xianwei Zhu, Shubin Wang, Jinbing Liu, Weiping Diao
Summary: This study investigated the role of key cytokines and metabolic factors in the formation of plant-type traits in pepper. Through integrated analysis of RNA-seq and metabolite determination, the study identified the low content of gibberellin and high content of auxin as important factors causing plant dwarfing, and jasmonic acid as a metabolic factor affecting branch traits. A total of 131 candidate genes involved in metabolite synthesis and the formation of plant-type traits were identified.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Yue Ma, Jia-Chen Hu, Yang Yu, Xin Cheng, Yan-Li Du, Qiang Zhao, Ji-Dao Du
Summary: Cadmium and drought stress significantly inhibited the growth of adzuki bean seedling plants, with the combined stress showing the highest degree of inhibition. Cd+D treatment reduced Cd accumulation in adzuki bean seedling roots. The treatment altered antioxidant enzyme activities and cell cycle phases in the roots, leading to changes in reactive oxygen species content.
SCIENTIA HORTICULTURAE
(2024)
Article
Horticulture
Lucette Adet, Danae M. A. Rozendaal, Arthur Tapi, Pieter A. Zuidema, Philippe Vaast, Niels P. R. Anten
Summary: This study investigated the effects of water stress on cocoa trees and found that they are highly sensitive to water stress, with different genotypes exhibiting varied responses. Potassium application did not mitigate the negative effects of water stress. There was significant variation among genotypes in terms of leaf and crown traits, and positive interactions between genotype and irrigation were observed. These findings provide insights into the acclimation strategies of cocoa trees and can be useful for selecting drought-tolerant genotypes.
SCIENTIA HORTICULTURAE
(2024)