Fetal liver: an ideal niche for hematopoietic stem cell expansion

Mapping the Mouse Cell Atlas by Microwell-Seq

(2018) Xiaoping Han et al.   CELL

The hematopoietic stem cell niche: from embryo to adult

(2018) Xin Gao et al.   DEVELOPMENT

BLOS2 maintains hematopoietic stem cells in the fetal liver via repressing Notch signaling

(2017) Qiuping He et al.   EXPERIMENTAL HEMATOLOGY

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq

(2017) Jun Chen et al.   Nature Protocols

Comprehensive Proteomic Characterization of Ontogenic Changes in Hematopoietic Stem and Progenitor Cells

(2017) Maria Jassinskaja et al.   Cell Reports

Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver

(2016) Stanislav Rybtsov et al.   DEVELOPMENT

Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo

(2016) Guangdun Peng et al.   DEVELOPMENTAL CELL

BRPF1 is essential for development of fetal hematopoietic stem cells

(2016) Linya You et al.   JOURNAL OF CLINICAL INVESTIGATION

Improved clinical outcomes of rhG-CSF-mobilized blood and marrow haploidentical transplantation compared to propensity score-matched rhG-CSF-primed peripheral blood stem cell haploidentical transplantation: a multicenter study

(2016) Xiangyu Zhao et al.   Science China-Life Sciences

ATF4 plays a pivotal role in the development of functional hematopoietic stem cells in mouse fetal liver

(2015) Y. Zhao et al.   BLOOD

Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

Design and Analysis of Single-Cell Sequencing Experiments

(2015) Dominic Grün et al.   CELL

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   IMMUNITY

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Fetal liver hematopoietic stem cell niches associate with portal vessels

(2015) J. A. Khan et al.   SCIENCE

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways

(2015) Javed K. Manesia et al.   Stem Cell Research

Three-dimensional growth dynamics of the liver in the human fetus

(2015) Michał Szpinda et al.   SURGICAL AND RADIOLOGIC ANATOMY

Three-dimensional growth dynamics of the liver in the human fetus

(2015) Michał Szpinda et al.   SURGICAL AND RADIOLOGIC ANATOMY

Effect of Developmental Stage of HSC and Recipient on Transplant Outcomes

(2014) Natasha Arora et al.   DEVELOPMENTAL CELL

The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells

(2014) D. M. Gerhardt et al.   GENES & DEVELOPMENT

OPN Induces FoxM1 Expression and Localization through ERK 1/2, AKT, and p38 Signaling Pathway in HEC-1A Cells

(2014) Yunpeng Xie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Validation of noise models for single-cell transcriptomics

(2014) Dominic Grün et al.   NATURE METHODS

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development

(2012) Zhuan Li et al.   Cell Stem Cell

The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny

(2012) Shannon McKinney-Freeman et al.   Cell Stem Cell

Immature hematopoietic stem cells undergo maturation in the fetal liver

(2012) A. Kieusseian et al.   DEVELOPMENT

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

(2012) Junke Zheng et al.   NATURE

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Self-Organization of Human Hepatic Organoid by Recapitulating Organogenesis In Vitro

(2012) T. Takebe et al.   TRANSPLANTATION PROCEEDINGS

Emergence of NK-cell progenitors and functionally competent NK-cell lineage subsets in the early mouse embryo

(2011) Y. Tang et al.   BLOOD

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells

(2011) M. Mochizuki-Kashio et al.   BLOOD

Establishment and regulation of the HSC niche: Roles of osteoblastic and vascular compartments

(2010) Suleyman Coskun et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations

(2010) J. Krosl et al.   BLOOD

Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver

(2010) H. Iwasaki et al.   BLOOD

The use of whole organ decellularization for the generation of a vascularized liver organoid

(2010) Pedro M. Baptista et al.   HEPATOLOGY

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells

(2010) Song Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Placenta as a source of hematopoietic stem cells

(2010) Elaine Dzierzak et al.   TRENDS IN MOLECULAR MEDICINE

Hematopoietic cytokines

(2008) D. Metcalf   BLOOD

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development

(2008) Prashanth Porayette et al.   DEVELOPMENTAL BIOLOGY

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

(2008) Tingting Li et al.   GENOMICS

Murine Hematopoietic Stem Cells and Multipotent Progenitors Express Truncated Intracellular Form of c-kit Receptor

(2008) Jennifer Zayas et al.   STEM CELLS AND DEVELOPMENT