Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement

Dynamo Catalogue : Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms

(2017) Daniel Castaño-Díez et al.   JOURNAL OF STRUCTURAL BIOLOGY

Automated tilt series alignment and tomographic reconstruction in IMOD

(2017) David N. Mastronarde et al.   JOURNAL OF STRUCTURAL BIOLOGY

Imaging complement by phase-plate cryo-electron tomography from initiation to pore formation

(2017) Thomas H. Sharp et al.   JOURNAL OF STRUCTURAL BIOLOGY

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

(2017) Simon A. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen

(2016) Guanbo Wang et al.   MOLECULAR CELL

A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface

(2016) Rob N. de Jong et al.   PLOS BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Semi-automated selection of cryo-EM particles in RELION-1.3

(2015) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

TEMPy: a Python library for assessment of three-dimensional electron microscopy density fits

(2015) Irene Farabella et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystal structure of deglycosylated human IgG4-Fc

(2014) Anna M. Davies et al.   MOLECULAR IMMUNOLOGY

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

(2014) Søren E. Degn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Deciphering the Fine Details of C1 Assembly and Activation Mechanisms: “Mission Impossible”?

(2014) Christine Gaboriaud et al.   Frontiers in Immunology

A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4

(2013) Andrew J. Perry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

(2013) Umakhanth Venkatraman Girija et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation

(2011) Alexandre R. Gingras et al.   STRUCTURE

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

(2010) Gregory L. Moore et al.   mAbs

Identification of the C1q-binding Sites of Human C1r and C1s

(2009) Isabelle Bally et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analogous Interactions in Initiating Complexes of the Classical and Lectin Pathways of Complement

(2009) A. E. Phillips et al.   JOURNAL OF IMMUNOLOGY