Article
Psychology, Clinical
Rob Sips, Zeno Van Duppen, Zuzana Kasanova, Lena De Thurah, Ana Teixeira, Jasper Feyaerts, Inez Myin-Germeys
Summary: Sudden insights, both aha and anti-aha experiences, are often reported by individuals with psychosis. The dialectic tension between these experiences may undermine a stable personal perspective.
PSYCHOSIS-PSYCHOLOGICAL SOCIAL AND INTEGRATIVE APPROACHES
(2021)
Review
Psychiatry
Barbara Hinterbuchinger, Nilufar Mossaheb
Summary: This narrative review highlights the focus on subclinical psychotic experiences, pointing out the diverse definitions, assessment tools, and concepts of psychotic-like experiences (PLEs) which may lead to inconsistent research results. It strongly recommends the use of a standardized assessment tool to achieve more comparable research findings in the future.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Feten Fekih-Romdhane, Diane El Hadathy, Covadonga Gonzalez-Nuevo, Diana Malaeb, Habib Barakat, Souheil Hallit
Summary: This study developed and validated a novel self-report measure, the Postpartum Psychotic Experiences Scale (PPES), for screening attenuated psychotic symptoms during the postpartum period. The PPES showed good convergent and concurrent validity, with high sensitivity and specificity.
PSYCHIATRY RESEARCH
(2023)
Article
Psychiatry
Christina Dardani, Rik Schalbroeck, Paul Madley-Dowd, Hannah J. Jones, Daniela Strelchuk, Gemma Hammerton, Jazz Croft, Sarah A. Sullivan, Stan Zammit, Jean-Paul Selten, Dheeraj Rai
Summary: This study found associations between childhood autistic traits and psychotic experiences until young adulthood, with childhood trauma playing an important role in mediating the relationship.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Biochemistry & Molecular Biology
Dominique Endres, Eva Luengen, Alkomiet Hasan, Michael Kluge, Sabrina Froehlich, Jan Lewerenz, Tom Bschor, Ida Sibylle Haussleiter, Georg Juckel, Florian Then Bergh, Barbara Ettrich, Lisa Kertzscher, Tatiana Oviedo-Salcedo, Robert Handreka, Martin Lauer, Klaas Winter, Norbert Zumdick, Anna Drews, Jost Obrocki, Yavor Yalachkov, Anna Bubl, Felix von Podewils, Udo Schneider, Kristina Szabo, Margarete Mattern, Alexandra Philipsen, Katharina Domschke, Klaus-Peter Wandinger, Alexandra Neyazi, Oliver Stich, Harald Pruess, Frank Leypoldt, Ludger Tebartz van Elst
Summary: Autoimmune encephalitis can manifest predominantly as psychiatric symptoms, especially in anti-NMDA receptor encephalitis. However, diagnosis in some patients is based on nonspecific findings and further research is needed.
MOLECULAR PSYCHIATRY
(2022)
Review
Behavioral Sciences
Eloi Gine Serven, Ester Boix Quintana, Maria Martinez Ramirez, Nicolau Guanyabens Busca, Desiree Muriana Batiste, Mar Guasp, Cristina Torres Rivas, Eva Davi Loscos, Virginia Casado Ruiz
Summary: Research has found that the cycloid psychosis (CP) phenotype is a common clinical presentation of psychiatric symptoms in patients with anti-NMDA receptor encephalitis (NMDARE), characterized by acute psychotic episodes with a sudden onset and a fluctuating clinical pattern, including confusion, delusions, hallucinations, motility disturbances, and mood oscillations. Patients who display the CP phenotype during their first psychotic episode should undergo cerebrospinal fluid analysis to rule out a possible diagnosis of autoimmune encephalitis.
BRAIN AND BEHAVIOR
(2021)
Article
Psychology, Clinical
M. Espinola-Nadurille, M. Restrepo-Martinez, L. Bayliss, E. Flores-Montes, V Rivas-Alonso, S. Vargas-Canas, L. Hernandez, I Martinez-Juarez, A. Gonzalez-Aguilar, R. Solis-Vivanco, G. L. Fricchione, J. Flores-Rivera, J. Ramirez-Bermudez
Summary: This study aimed to determine the behavioral hallmarks of anti-NMDA receptor encephalitis (ANMDARE). After systematic neuropsychiatric and cognitive assessments on 160 patients, the typical neuropsychiatric patterns of ANMDARE were found to be psychosis, delirium, catatonia, anxiety-depression, and mania. Cognitive function was also significantly impaired, with 34% of patients presenting predominantly neuropsychiatric symptoms without seizures.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
M. J. Bosma, S. R. Cox, T. Ziermans, C. R. Buchanan, X. Shen, E. M. Tucker-Drob, M. J. Adams, H. C. Whalley, S. M. Lawrie
Summary: This study reveals that lower global white matter microstructure is associated with having PLEs in combination with distress, suggesting a direction of future research. Additionally, it replicates the finding that processing speed mediates the relationship between white matter microstructure and g-factor.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Nicola Warren, Cullen O'Gorman, Gemma McKeon, Andrew Swayne, Stefan Blum, Dan Siskind
Summary: Anti-NMDAR encephalitis is an immune-mediated disorder requiring multi-disciplinary treatment. Psychiatric symptoms are common and treated with antipsychotics, but may not be effective in improving psychosis, affective symptoms or catatonia. Primary treatment should focus on immunotherapy, with antipsychotic medications useful for managing agitation and aggression.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychiatry
Lindsay A. Bornheimer, Meghan E. Martz, Takakuni Suzuki, Ivy F. Tso, Cynthia Z. Burton, Juliann Li Verdugo, Tyler Grove, Mary M. Heitzeg, Stephan F. Taylor
Summary: The study found important relationships between affective dysregulation (AD) and psychosis-like symptoms (PLE), which vary with developmental stage. AD in mid-teen years predicted subsequent PLE 3 years later, while increasing PLE in the end of teen years related to a subsequent increase in AD in early 20s.
SCHIZOPHRENIA BULLETIN
(2022)
Article
Neurosciences
Jeremy A. Taylor, Kit Melissa Larsen, Ilvana Dzafic, Marta I. Garrido
Summary: This study applied machine learning methods and EEG data to predict subclinical psychotic-like experiences in healthy individuals, demonstrating that EEG data alone can predict individual psychotic-like experiences. Features within specific time windows contributed to different levels of Prodromal Questionnaire scores, supporting the idea that psychosis may exist on a continuum expanding into the non-clinical population.
Article
Psychiatry
Lukasz Gaweda, Renata Pionke, Jessica Hartmann, Barnaby Nelson, Andrzej Cechnicki, Dorota Frydecka
Summary: The study examined the link between traumatic life events and psychotic-like experiences in young adults, finding that exposure to sexual trauma played a central role in influencing PLEs. The pathways from trauma to PLEs were identified to involve cognitive biases and depressive symptoms, but the shortest pathway did not include these factors. The findings highlight the importance of environmental adversities, dysfunctional information processing, and depression in the network of psychosis risks.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Psychiatry
Ryan Turner, Krisya Louie, Ameerah Parvez, Mustapha Modaffar, Rowan Rezaie, Talya Greene, James Bisby, Peter Fonagy, Michael A. P. Bloomfield
Summary: Developmental trauma is associated with psychotic experiences, and deficits in Theory of Mind (ToM) are a candidate mechanism underlying the association between developmental trauma and psychosis.
PSYCHIATRY RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Petr Bob, Tereza Petraskova Touskova, Ondrej Pec, Jiri Raboch, Nash Boutros, Paul Lysaker
Summary: This study found a significant correlation between hair cortisol levels and stress symptoms as well as complex partial seizure-like symptoms in patients experiencing their initial episode of psychosis. However, there was no significant correlation between hair cortisol levels and symptoms of anxiety and depression. These findings suggest a potential relationship between epileptic-like symptoms and stress responses in patients during their first psychotic episode.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
B. Hinterbuchinger, M. Koch, M. Trimmel, Z. Litvan, J. Baumgartner, E. L. Meyer, F. Friedrich, N. Mossaheb
Summary: This study examines the prevalence of psychotic-like experiences (PLEs) in individuals with different beliefs and finds that a tendency towards supernatural beliefs is associated with higher PLEs scores.
Article
Psychiatry
Zeno Van Duppen, Rob Sips
Article
Psychology, Clinical
Rob Sips, Zeno Van Duppen, Zuzana Kasanova, Lena De Thurah, Ana Teixeira, Jasper Feyaerts, Inez Myin-Germeys
Summary: Sudden insights, both aha and anti-aha experiences, are often reported by individuals with psychosis. The dialectic tension between these experiences may undermine a stable personal perspective.
PSYCHOSIS-PSYCHOLOGICAL SOCIAL AND INTEGRATIVE APPROACHES
(2021)
