Synthesis and cytotoxicity of novel dispiro derivatives of 5-arylidenoxazolones, potential inhibitors of p53—MDM2 protein-protein interaction

Organic chemistry. History and mutual relations of universities of Russia

(2017) I. S. Antipin et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Discovery of Novel Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2–p53 Interaction

(2016) Andreas Gollner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological testing of (5Z)-2-aryl-5-arylmethylidene-3,5-dihydro-4H-imidazol-4-ones as antimitotic agents

(2016) Anastasia A. Beloglazkina et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis and biological evaluation of novel potent MDM2/p53 small-molecule inhibitors

(2015) Yan A. Ivanenkov et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluation

(2015) Hui Dong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Computational analysis of spiro-oxindole inhibitors of the MDM2-p53 interaction: insights and selection of novel inhibitors

(2015) Wei Huang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs

(2015) E. S. Barskaia et al.   RUSSIAN CHEMICAL BULLETIN

Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy

(2014) Zhuming Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

SAR405838: An Optimized Inhibitor of MDM2-p53 Interaction That Induces Complete and Durable Tumor Regression

(2014) S. Wang et al.   CANCER RESEARCH

Recent advances in the synthesis of biologically active spirooxindoles

(2014) Maria M.M. Santos   TETRAHEDRON

Efficient and Regioselective Synthesis of Novel Functionalized Dispiropyrrolidines and Their Cytotoxic Activities

(2014) Jin-Ming Yang et al.   ACS Combinatorial Science

Diastereomeric Spirooxindoles as Highly Potent and Efficacious MDM2 Inhibitors

(2013) Yujun Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of a Spiroindolinone Pyrrolidinecarboxamide MDM2 Antagonist

(2013) Lianhe Shu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development

(2013) Zhuming Zhang et al.   ACS Medicinal Chemistry Letters

DNA methylation inhibitors in cancer: Recent and future approaches

(2012) Christina Gros et al.   BIOCHIMIE

Excited-State Intramolecular Proton Transfer Molecules Bearingo-Hydroxy Analogues of Green Fluorescent Protein Chromophore

(2011) Wei-Ti Chuang et al.   JOURNAL OF ORGANIC CHEMISTRY

Identification of the Spiro(oxindole-3,3′-thiazolidine)-Based Derivatives as Potential p53 Activity Modulators

(2010) Isabel Gomez-Monterrey et al.   JOURNAL OF MEDICINAL CHEMISTRY