Article
Medicine, General & Internal
Patrick J. Campbell, David R. Axon, Ann M. Taylor, Karen Smith, Matthew Pickering, Heather Black, Terri Warholak, Chanadda Chinthammit
Summary: Limited evidence exists on the relationships between adherence, healthcare utilization, and economic outcomes among Medicare Supplemental beneficiaries. This study aimed to assess the relationship between adherence and utilization and cost over a 1-year period, finding that adherence was associated with lower healthcare utilization and expenditures across different disease cohorts.
Article
Cardiac & Cardiovascular Systems
R. Angel Garcia, John A. Spertus, Mary C. Benton, Philip G. Jones, Daniel B. Mark, Jonathan D. Newman, Sripal Bangalore, William E. Boden, Gregg W. Stone, Harmony R. Reynolds, Judith S. Hochman, David J. Maron
Summary: The ISCHEMIA trial examined the association between medication adherence and health status outcomes in patients with chronic coronary disease. The study found that nonadherence to medication was associated with worse health status at baseline and 12 months, regardless of treatment strategy. Strategies to improve medication adherence are needed to improve health status outcomes in patients with chronic coronary disease.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Carmen Corral-Partearroyo, Alba Sanchez-Vinas, Montserrat Gil-Girbau, Maria Teresa Penarrubia-Maria, Ignacio Aznar-Lou, Antoni Serrano-Blanco, Cristina Carbonell-Duacastella, Carmen Gallardo-Gonzalez, Maria Del Carmen Olmos-Palenzuela, Maria Rubio-Valera
Summary: This study evaluates the feasibility and acceptability of the Initial Medication Adherence (IMA) intervention and the possibility of conducting a cluster-RCT to assess its effectiveness and cost-effectiveness. The findings suggest that the IMA intervention is feasible and acceptable, but there are barriers that need to be addressed.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Pharmacology & Pharmacy
Sara Daliri, Marcel J. Kooij, Wilma J. M. Scholte Op Reimer, Gerben Riet, Patricia Jepma, Lotte Verweij, Ron J. G. Peters, Bianca M. Buurman, Fatma Karapinar-Carkit
Summary: The multi-component intervention targeting medication adherence in older cardiac patients discharged from hospital did not significantly improve their medication adherence levels, with a potential modest positive effect only seen in those not using an MDD system. This finding requires further replication.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Bronwyn Myers, Carl J. Lombard, Crick Lund, John A. Joska, Naomi Levitt, Tracey Naledi, Petal Petersen Williams, Claire van der Westhuizen, Pim Cuijpers, Dan J. Stein, Katherine R. Sorsdahl
Summary: This study compares the effectiveness of dedicated community health workers (CHWs), designated CHWs, and treatment as usual for patients with chronic physical diseases. The results showed that both the dedicated and designated groups had greater improvement in depression scores at 12 months, while reductions in alcohol use scores were similar across all groups. This study extends the evidence for CHW-delivered psychological interventions and provides insights into the effect of different delivery approaches on patient outcomes.
Article
Medicine, Research & Experimental
JoAnn M. Sperl-Hillen, Jacob L. Haapala, Steven P. Dehmer, Lilian N. Chumba, Heidi L. Ekstrom, Anjali R. Truitt, Stephen E. Asche, Ann M. Werner, Dan J. Rehrauer, Melissa A. Pankonin, Pamala A. Pawloski, Patrick J. O'Connor
Summary: This article describes the original and adapted protocols of a randomized trial to improve medication adherence for cardiometabolic conditions. Protocol adaptation became imperative in response to major implementation challenges.
CONTEMPORARY CLINICAL TRIALS
(2024)
Article
Medicine, General & Internal
Anusha Naik, Solomiya Syvyk, Jason Tong, Chris Wirtalla, Frances K. Barg, Carmen E. Guerra, Shivan J. Mehta, Richard Wender, Raina M. Merchant, Rachel R. Kelz
Summary: This study compares the factors considered by primary care physicians when making prescription medication recommendations vs referral recommendations for surgery. The findings reveal that physicians rely on objective data and patient attributes for medication recommendations, while subjective factors, such as personal experience and beliefs, play a dominant role in surgeon and hospital referrals. Introducing accessible and reliable surgical data is crucial for improving the referral process and surgical outcomes.
Article
Medicine, General & Internal
Terri R. Fried, Manshu Yang, Steve Martino, Lynne Iannone, Maria Zenoni, Laura Blakley, John R. O'Leary, Colleen A. Redding, Andrea L. Paiva
Summary: This study examined the efficacy of computer-tailored print feedback, motivational interviewing, and motivational enhancement therapy on completion of a set of advance care planning (ACP) activities. The results showed that motivational interviewing and motivational enhancement therapy significantly increased the proportion of middle-aged and older veterans completing the ACP activities.
JAMA INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Kyle Possemato, Emily Johnson, Kimberly Barrie, Sharfun Ghaus, Delilah Noronha, Michael Wade, Mark A. Greenbaum, Craig Rosen, Marylene Cloitre, Jason Owen, Shaili Jain, Gregory Beehler, Annabel Prins, Karen Seal, Eric Kuhn
Summary: This study tested the effectiveness of a brief primary care-based treatment in reducing the severity of PTSD and improving patient satisfaction. The results showed that the treatment resulted in more patient-reported symptom relief and higher treatment satisfaction, but did not show a significant improvement in clinician-rated PTSD severity.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Matthew Jones, Ralph K. Akyea, Katherine Payne, Steve E. Humphries, Hasidah Abdul-Hamid, Stephen Weng, Nadeem Qureshi
Summary: This study determines the cost-effectiveness of six case-finding strategies for screening of electronic health records to identify index patients who have genetically confirmed monogenic FH in English primary care. FAMCAT2 was found to be the most cost-effective screening approach.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Nursing
Chen Yang, Diana Tze Fan Lee, Xiuhua Wang, Sek Ying Chair
Summary: This study evaluated a nurse-led medication self-management intervention for older people with multimorbidity. The intervention showed significant improvements in medication adherence, medication knowledge, beliefs about harm of medication, medication self-efficacy, and satisfaction with convenience of medication use. However, no significant effects were found on quality of life and utilisation of health care services.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Chemistry, Multidisciplinary
Maria del Carmen Gonzalez-Lopez, Carlos Ruiz-Gonzalez, Bruno Jose Nievas-Soriano, Sonia Garcia-Duarte, Tesifon Parron-Carreno
Summary: The study found that after hospital discharge, most patients in primary health care showed medication discrepancies in their records, with medication errors being the most common type of discrepancy, especially medication omission. Women aged 65 and older were more likely to have medication errors.
APPLIED SCIENCES-BASEL
(2021)
Article
Public, Environmental & Occupational Health
Aikaterini Kassavou, Charlotte A. Court, Venus Mirzaei, James Brimicombe, Simon Edwards, Stephen Sutton
Summary: The digital intervention was found to be effective at improving medication adherence in non-adherent patients with Hypertension or Type 2 Diabetes. Positive changes in underlying mechanisms of behavior change were associated with intervention effectiveness. Subjective accounts highlighted the support of motivation and ability to adhere, with brief medication adherence risk appraisal and ongoing digitally delivered behavioral support recommended for clinical impact.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Nursing
Reza Hajialibeigloo, Seyed Reza Mazlum, Samira Mohajer, Donald E. Morisky
Summary: The study findings indicate that the self-administration of medication programme can significantly improve medication adherence levels in cardiovascular patients and increase nurse satisfaction.
Article
Medicine, General & Internal
Julie C. Lauffenburger, Renee A. Barlev, Rasha Khatib, Nicole Glowacki, Alvia Siddiqi, Marlon E. Everett, Michelle A. Albert, Punam A. Keller, Lipika Samal, Kaitlin Hanken, Ellen S. Sears, Nancy Haff, Niteesh K. Choudhry
Summary: This qualitative study examines the perspectives of primary care providers and patients on barriers and facilitators to hypertension control in a racially and ethnically diverse healthcare system. The study reveals that lifestyle modifications may be more important than medications for hypertension, especially for patients from racial and ethnic minority groups. Participants also expressed concerns about the functionality of health information technology tools in supporting hypertension care.
Review
Chemistry, Analytical
M. Fraga-Corral, M. Carpena, P. Garcia-Oliveira, A. G. Pereira, M. A. Prieto, J. Simal-Gandara
Summary: Metabolomics is a young field of knowledge that seeks to understand metabolites and their mechanisms of action. Various techniques such as NMR, MS, and VS are used to study the metabolome of biological samples. Each technique has its own advantages and limitations, and the choice depends on the research objectives and nature of the samples. Metabolomics has applications in environmental, food, and health sciences, and its growth is supported by advances in analytical techniques and integration with other omics.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Letter
Rheumatology
Sindhu R. Johnson, Martin Aringer
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Acoustics
Cristina Ramos-Hernandez, Maribel Botana-Rial, Cecilia Mouronte-Roibas, Marta Nunez-Fernandez, Almudena Gonzalez-Montaos, Adriana Carolina Caldera-Diaz, Alberto Ruano-Ravina, Alberto Fernandez-Villar
Summary: This study aimed to evaluate the diagnostic contribution and treatment changes after performing protocolized lung ultrasound (LUS) in patients hospitalized in a Pulmonology Department ward. Results showed that LUS provided additive information in more than half of patients, potentially leading to reclassification or changes in diagnosis or treatment.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Review
Biology
Ramon C. Hermida, Artemio Mojon, Jose R. Fernandez, Ramon G. Hermida-Ayala, Juan J. Crespo, Maria T. Rios, Manuel Dominguez-Sardina, Alfonso Otero, Michael H. Smolensky
Summary: Elevated asleep blood pressure and blunted sleep-time relative systolic blood pressure decline are significant prognostic markers of cardiovascular disease risk. Current hypertension guidelines overlook the importance of asleep blood pressure and recommend diagnosis based on office blood pressure measurements. Studies have shown that taking blood pressure-lowering medications at bedtime results in greater reduction of blood pressure and improved cardiovascular outcomes compared to morning intake.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Dermatology
Veronica Ruiz-Salas, Onofre Sanmartin-Jimenez, Joan R. Garces, Eva Vilarrasa, Roman Minano-Medrano, Begona Escutia-Munoz, Angeles Florez-Menendez, Juan L. Artola-Igarza, Alberto Alfaro-Rubio, Pedro Redondo, Yolanda Delgado-Jimenez, Julia Sanchez-Schmidt, Irati Allende-Markixana, Beatriz Garcia Bracamonte, Pablo de la Cueva-dobao, Cristina Ciudad, Lucia Carnero-Gonzalez, Hugo Vazquez-Veiga, Pedro Sanchez-Sambucety, Jose Luis Estebaranz, Rafael Botella-Estrada, Beatriz Gonzalez-Sixto, Antonio Martorell, Victoriano Morales-Gordillo, Agusti Toll-Abello, Matias Mayor-Arenal, Ricardo Suarez-Fernandez, Laura Sainz-Gaspar, Miguel A. Descalzo, Ignacio Garcia-Doval
Summary: This study found that the risk of complications in MMS surgery is low, mainly related to tumor size and depth. The use of anticoagulant/antiaggregant slightly increased the risk of hemorrhage. Age and outpatient setting were not associated with the risk of complications.
Article
Computer Science, Artificial Intelligence
Alba Nogueira-Rodriguez, Ruben Dominguez-Carbajales, Fernando Campos-Tato, Jesus Herrero, Manuel Puga, David Remedios, Laura Rivas, Eloy Sanchez, Agueda Iglesias, Joaquin Cubiella, Florentino Fdez-Riverola, Hugo Lopez-Fernandez, Miguel Reboiro-Jato, Daniel Glez-Pena
Summary: The study developed a deep learning model for real-time polyp detection based on the YOLOv3 architecture, complemented with an object-tracking algorithm for post-processing to reduce false positives. Results showed varying predictive performance for different types of polyp morphologies and the use of narrow band imaging, with the object-tracking algorithm significantly improving specificity while maintaining sensitivity.
NEURAL COMPUTING & APPLICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Clara Otero-Martinez, Junzhi Ye, Jooyoung Sung, Isabel Pastoriza-Santos, Jorge Perez-Juste, Zhiguo Xia, Akshay Rao, Robert L. Z. Hoye, Lakshminarayana Polavarapu
Summary: Colloidal metal-halide perovskite nanocrystals have gained attention for their exciting properties and tunable emission range. However, they are limited by light-induced halide phase segregation. By controlling the thickness, monolayer nanoplatelets with narrow emission peaks and high radiative recombination can be synthesized, making them ideal for efficient LEDs.
ADVANCED MATERIALS
(2022)
Review
Pharmacology & Pharmacy
Nerea Garcia-Beloso, Irene Altabas-Gonzalez, Marisol Samartin-Ucha, Monica Gayoso-Rey, Maria Luisa De Castro-Parga, Angel Salgado-Barreira, Amelia Cibeira-Badia, Maria Guadalupe Pineiro-Corrales, Daniel Gonzalez-Vilas, Jose Maria Pego-Reigosa, Noemi Martinez-Lopez de Castro
Summary: From January 1, 2004 to June 30, 2021, a systematic review of studies on switching between reference adalimumab and biosimilars in different chronic immune-mediated inflammatory diseases found that the efficacy, safety, and immunogenicity were not affected by the switch. The findings were consistent across different adalimumab biosimilars and may be extended to other rheumatic diseases like psoriatic arthritis and ankylosing spondylitis.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Timothy Williams, Aaina Mittal, Dimitar Karageorgiev, Andres Iniguez Romo, Adel Aminian, Javier Fernandez Portalese, Elyes Kharrat, Joan Antoni Gomez-Hospital, Doni Firman, Ramiro Trillo Nouche, David Hildick-Smith
Summary: This analysis aimed to evaluate the effect of coronary revascularization strategy during index admission on clinical outcomes among patients undergoing PCI with MVD. The results showed that a complete revascularization strategy resulted in lower rates of target lesion failure, patient-oriented composite endpoint events, and all-cause mortality at 1 year compared to an incomplete revascularization strategy.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Ignacio J. Amat-Santos, Juan P. Sanchez-Luna, Emad Abu-Assi, Maria Melendo-Viu, Ignacio Cruz-Gonzalez, Luis Nombela-Franco, Antonio J. Munoz-Garci, Sergio G. Blas, Jose M. de la Torre Hernandez, Rafael Romaguera, Angel Sanchez-Recalde, Jose L. Diez-Gil, Diego Lopez-Otero, Livia Gheorge, Borja Ibanez, Andres Iniguez-Romo, Sergio Raposeiras-Roubin
Summary: The DapaTAVI trial aims to evaluate the efficacy and safety of dapagliflozin in patients with severe AS undergoing TAVI. Candidate patients should have prior history of HF admission and meet criteria such as diabetes mellitus, reduced left ventricular ejection fraction, or certain estimated glomerular filtration rate. The trial will involve 1020 patients who will be randomized to receive dapagliflozin or no dapagliflozin, with key secondary outcomes including HF hospitalization, cardiovascular mortality, and total number of HF rehospitalizations.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Luis Marroquin, Gabriela Tirado-Conte, Radoslaw Praco, Witold Streb, Hipolito Gutierrez, Giacomo Boccuzzi, Dabit Arzamendi-Aizpurua, Ignacio Cruz-Gonzalez, Juan Miguel Ruiz-Nodar, Jung-Sun Kim, Xavier Freixa, Jose Ramon Lopez-Minguez, Ole De Backer, Rafael Ruiz-Salmeron, Antonio Dominguez, Angela McInerney, Vicente Peral, Rodrigo Estevez-Loureiro, Eduard Fernandez-Nofrerias, Afonso B. Freitas-Ferraz, Francesco Saia, Zenon Huczek, Livia Gheorghe, Pablo Salinas, Marcin Demkow, Jose R. Delgado-Arana, Estefania Fernandez Peregrina, Zbibniew Kalarus, Ana Elvira Laffond, Yangsoo Jang, Jose Carlos Fernandez Camacho, Oh-Hyun Lee, Jose M. Hernandez-Garcia, Caterina Mas-Llado, Berenice Caneiro Queija, Ignacio J. Amat-Santos, Maciej Dabrowski, Josep Rodes-Cabau, Luis Nombela Franco
Summary: This study analyzed the medical and invasive treatment of patients referred for LAAC in the presence of LAA thrombus. The initial preferred strategy was IAT, with a relatively high thrombus resolution rate but also a higher bleeding rate. Direct LAAC was found to be feasible with high procedural success, but a high rate of device-related thrombosis was detected during follow-up.
Review
Gastroenterology & Hepatology
Vincenzo Vigorita, Oscar Cano-Valderrama, Valerio Celentano, Danilo Vinci, Monica Millan, Antonino Spinelli, Gianluca Pellino
Summary: Evidence on ERAS in IBD is lacking, but this group of patients might benefit from consistent adoption of the pathway. Future studies should define if IBD-specific ERAS pathways and selection criteria are needed.
JOURNAL OF CROHNS & COLITIS
(2022)
Article
Environmental Sciences
Joseba Rabanales-Sotos, Isabel Maria Guisado-Requena, Zoila Esperanza Leiton-Espinoza, Carmen Maria Guerrero-Agenjo, Jesus Lopez-Torres-Hidalgo, Jose Luis Martin-Conty, Francisco Martin-Rodriguez, Jaime Lopez-Tendero, Angel Lopez-Gonzalez
Summary: This study examined the performance of a novel low-cost, ultra-compact, and attractive auditory feedback device for training laypeople in external chest compressions (ECCs). The results showed that the device was effective in teaching and learning basic CPR, and it could discriminate between those who performed correct ECCs according to their BMI and muscle strength and those who did not.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Carmen Maria Guerrero-Agenjo, Jaime Lopez-Tendero, Angel Lopez-Gonzalez, Isabel Maria Guisado-Requena, Jose Alberto Laredo-Aguilera, Juan Manuel Carmona-Torres, Jesus Lopez-Torres-Hidalgo, Joseba Rabanales-Sotos
Summary: The study aimed to estimate the frequency of alcohol consumption in nursing students and describe the pattern of alcohol consumption after COVID-19 lockdown. It found that 36.7% of students met the criteria for excessive alcohol consumption, and the prevalence of hazardous drinkers was 10.2%. Women and smokers had a higher percentage of hazardous drinking. The study suggests the need for strategies promoting healthy lifestyles and preventive activities against excessive alcohol consumption, as well as including a gender perspective.
Article
Ethics
Cesar R. Torres, Francisco Javier Lopez Frias, Maria Jose Martinez Patino
Summary: This article scrutinizes viewpoints that justify exclusionary policies for transgender athletes based on physiological criteria and argues for the importance of considering lived body and embodied experience in the discussion. The author contends that assessing the inclusion of transgender athletes should go beyond physiological criteria and incorporate the notion of embodied advantage.
SPORT ETHICS AND PHILOSOPHY
(2022)