Article
Chemistry, Applied
Verica Aleksic Sabo, Isidora Nikolic, Neda Mimica-Dukic, Petar Knezevic
Summary: The study found that carvacrol, thymol, and eugenol exhibited good antibacterial activity against A. baumannii, especially when used in combination with ciprofloxacin. The synergistic effect was confirmed by the time kill curve method.
NATURAL PRODUCT RESEARCH
(2021)
Review
Pharmacology & Pharmacy
Laeza Alves Sampaio, Licia Tairiny Santos Pina, Mairim Russo Serafini, Debora dos Santos Tavares, Adriana Gibara Guimaraes
Summary: Carvacrol and thymol, natural compounds, exhibit antitumor and antiproliferative activities by acting through multiple signaling pathways. Carvacrol appears to be more potent than thymol in vitro, but further in vivo studies are needed to determine safe doses, toxic effects, and clarify exact mechanisms of action.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Food Science & Technology
Wu Wang, Tingting Li, Jing Chen, Yingwang Ye
Summary: This research investigates the antibacterial potential of plant essential oil components against Salmonella Enteritidis. Thymol, carvacrol, and cinnamaldehyde were found to have the best inhibitory effect on S. Enteritidis. Thymol and carvacrol not only maintained the sensory quality of chicken, but also reduced pH, moisture content, and TVB-N value.
Article
Food Science & Technology
Charlene Leneveu-Jenvrin, Aouatif Aboudia, Sophie Assemat, Fabienne Remize
Summary: The addition of thyme and Moroccan thyme essential oils inhibits fungal growth in pineapple juice, extending its shelf life. The low pH of the juice enhances the antifungal effect of the compounds. Despite the addition of thyme scent, the characteristic pineapple and sugary descriptors are maintained.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Sandra T. Krause, Pan Liao, Christoph Crocoll, Benoit Boachon, Christiane Foerster, Franziska Leidecker, Natalie Wiese, Dongyan Zhao, Joshua C. Wood, C. Robin Buell, Jonathan Gershenzon, Natalia Dudareva, Joerg Degenhardt
Summary: Thymol and carvacrol are phenolic monoterpenes with antibacterial and anti-spasmolytic properties. Their biosynthesis involves cyclization and oxidation reactions, with specific enzymes playing key roles. The study provides new insights into the formation mechanism of these compounds.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Food Science & Technology
Cristina Fuentes, Samuel Verdu, Ana Fuentes, Maria Jose Ruiz, Jose Manuel Barat
Summary: The study evaluated the toxicity of four widely used essential oil components on nematodes and found that these compounds had a concentration-dependent effect on nematode survival at moderate to high concentrations, with reproduction being a more sensitive endpoint for toxicity evaluation. The findings suggest that these compounds can be toxic at lower doses than those required for their biological action.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Food Science & Technology
Tareq M. Osaili, Fayeza Hasan, Dinesh Kumar Dhanasekaran, Reyad S. Obaid, Anas A. Al-Nabulsi, Mutamed Ayyash, Layal Karam, Ioannis N. Savvaidis, Richard Holley
Summary: The study evaluated the antimicrobial effect of active essential oil components on Listeria monocytogenes, Salmonella spp., and Escherichia coli O157:H7 in chicken tawook during storage. Results showed that the marinade significantly reduced L. monocytogenes and Salmonella spp. numbers at 10°C, while the addition of essential oils did not affect the pathogen populations.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Yoli Mariana Medina-Romero, Ana Bertha Hernandez-Hernandez, Marco Aurelio Rodriguez-Monroy, Maria Margarita Canales-Martinez
Summary: The study evaluated the biopesticide activity of Bursera morelensis and Lippia graveolens essential oils, finding their antifungal properties which make them promising candidates for environmentally friendly agricultural production.
SCIENTIFIC REPORTS
(2021)
Article
Plant Sciences
Johannes-Paul Fladerer, Selina Grollitsch, Franz Bucar
Summary: Effective strategies for management of antimicrobial resistant pathogens include revitalizing already existing antimicrobials and combination therapies. This study developed a screening method for testing multiple drug interactions of herbal drugs, which is cost-saving and time-saving compared to traditional methods.
PHYTOCHEMISTRY LETTERS
(2023)
Article
Medicine, Research & Experimental
Isis Caroline da Silva Cirino, Caroline Ferreira de Santana, Maria Jose Ribeiro Bezerra, Igor Vasconcelos Rocha, Ana Carolina de Oliveira Luz, Henrique Douglas Melo Coutinho, Regina Celia Bressan Queiroz de Figueiredo, Antonio Raposo, Linda Heejung Lho, Heesup Han, Tereza Cristina Leal-Balbino
Summary: This study evaluated the antibacterial activity of thymol and carvacrol against multidrug-resistant Acinetobacter baumannii. The results showed that thymol and carvacrol alone effectively inhibited the bacterial growth, and their combination exhibited synergistic or additive effects. Transcriptomic analysis revealed the regulation of stress response pathways.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Medicine, Research & Experimental
Katherine Miranda-Cadena, Cristina Marcos-Arias, Estibaliz Mateo, Jose Manuel Aguirre-Urizar, Guillermo Quindos, Elena Eraso
Summary: The study evaluated the effects of three phytocompounds on Candida planktonic and sessile cells, with cinnamaldehyde being the most active in inhibiting biofilm adhesion, while carvacrol and thymol significantly reduced both mature biofilm biomass and metabolic activity. These results highlight the potential of cinnamaldehyde, carvacrol, and thymol as promising alternatives for candidiasis treatment and emphasize the need for further research on their safety, toxicity, pharmacodynamics, and pharmacokinetics.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Agricultural Engineering
Fernanda Tomiotto-Pellissier, Bruna Taciane da Silva Bortoleti, Virginia Marcia Concato, Ana Flavia Marques Ganaza, Ana Carolina Quasne, Beatriz Ricci, Pedro Vinicius Dolce E Carvalho, Gustavo Henrique Della Colleta, Danielle Lazarin-Bidoia, Taylon Felipe Silva, Manoela Daiele Goncalves, Renata Katsuko Takayama Kobayashi, Gerson Nakazato, Idessania Nazareth Costa, Ivete Conchon-Costa, Milena Menegazzo Miranda-Sapla, Wander Rogerio Pavanelli
Summary: This study investigated the leishmanicidal and immunomodulatory effects of oregano essential oil (OEO) on experimental Leishmania amazonensis-model through in silico, in vitro, and in vivo approaches. The results demonstrated that OEO containing carvacrol, thymol, gamma-terpinene, p-cymene, and beta-caryophyllene as the main components showed potential as an oral and topical drug development for the treatment of L. amazonensis. OEO exhibited leishmanicidal activity by inducing a combination of autophagic, apoptotic, and necrotic events, and had immunomodulatory effects without triggering a pro-inflammatory response.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Maciej Walczak, Marta Michalska-Sionkowska, Daria Olkiewicz, Patrycja Tarnawska, Oliwia Warzynska
Summary: The study showed that thymol and carvacrol can effectively inhibit biofilm formation and enzyme activity of Staphylococcus aureus and Pseudomonas aeruginosa, with high antimicrobial properties demonstrated in both 3-day and 10-day experiments.
Review
Veterinary Sciences
Majid Gholami-Ahangaran, Asiye Ahmadi-Dastgerdi, Shahrzad Azizi, Asal Basiratpour, Maryam Zokaei, Masoud Derakhshan
Summary: This study discusses the role of thymol and carvacrol in poultry production, showing that these natural compounds have a wide range of biological activities, including promoting growth, improving feed utilization, and protecting the liver in chickens. Additionally, they can impact egg composition, quality, and chicken behavior.
VETERINARY MEDICINE AND SCIENCE
(2022)
Article
Plant Sciences
Valiollah Mohammadi, Samaneh Talebi, Masoumeh Ahmadnasab, Hossein Mollahassanzadeh
Summary: Inducing polyploidy in Thymus vulgaris leads to larger vegetative and reproductive plant organs. The application of colchicine at a concentration of 0.3% on 4-leaf seedlings for 6 hours resulted in the highest survival rate and the highest number of tetraploid plants. Tetraploid plants exhibited significant morphological and physiological differences compared to diploid plants.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Food Science & Technology
Carlos Enrique Ochoa-Velasco, Julio Cesar Perez-Perez, Jose Mauricio Varillas-Torres, Addi Rhode Navarro-Cruz, Paola Hernandez-Carranza, Ricardo Munguia-Perez, Teresa Soledad Cid-Perez, Raul Avila-Sosa
Summary: This study evaluated the effectiveness of thymol and carvacrol against Colletotrichum gloeosporioides in edible films and coatings. In vitro evaluation showed MIC values of the compounds at different pH levels, with additive effects observed in binary mixtures. In vivo evaluation on mango and papaya demonstrated delayed fruit ripening and reduced disease symptoms, indicating the potential of thymol and carvacrol in controlling anthracnose.
Article
Food Science & Technology
Karen Y. Jattar-Santiago, Carolina Ramirez-Lopez, Paola Hernandez-Carranza, Raul Avila-Sosa, Irving I. Ruiz-Lopez, Carlos E. Ochoa-Velasco
Summary: This study evaluated the effect of different solid-to-solvent ratios, temperatures, and times on the extraction of bioactive compounds from habanero pepper. The optimal conditions for extraction were identified, and the extract showed antimicrobial and antioxidant properties.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Nutrition & Dietetics
Orietta Segura-Badilla, Ashuin Kammar-Garcia, Addi Rhode Navarro-Cruz, Jacqueline Araneda-Flores, Javier Mancilla-Galindo, Obdulia Vera-Lopez, Martin Lazcano-Hernandez, Gladys Quezada-Figueroa
Summary: As the population ages, greater attention to age-related health problems related to diet and lifestyles is needed. This study found that most older adults in a southern Chilean commune were living in vulnerable or poverty conditions, and their diet quality was in need of improvement.
Article
Nutrition & Dietetics
Malda Atasi, Ashuin Kammar-Garcia, Rafael Almendra-Pegueros, Addi Rhode Navarro-Cruz
Summary: The study found that metabolic syndrome and its components are associated with dietary patterns high in calories, protein, simple carbohydrates, and saturated fat.
JOURNAL OF NUTRITION AND METABOLISM
(2022)
Article
Biotechnology & Applied Microbiology
Miriam Toxqui-Munguia, Raul Avila-Sosa, Elsa Castaneda-Roldan, Esperanza Duarte-Escalante, Dolores Castaneda-Antonio, Gloria Leon-Tello, Ricardo Munguia-Perez
Summary: This study aimed to identify bacteria and yeasts in milk samples from dairy cattle with subclinical mastitis and evaluate their susceptibility to antimicrobials. It was found that Candida glabrata and C. krusei were the dominant yeasts, while Staphylococcus saprophyticus and S. aureus were the most common bacteria. Additionally, resistance to some commonly used antimicrobials was observed in these pathogens.
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2022)
Article
Engineering, Chemical
M. Aguirre-Garcia, O. Cortes-Zavaleta, H. Ruiz-Espinosa, C. E. Ochoa-Velasco, I. I. Ruiz-Lopez
Summary: The objective of this study was to develop a new model considering the coupled mass transport of water and solute occurring during osmotic dehydration (OD) of foods and evaluate its contribution on the estimation of mass transfer properties. Experimental results demonstrated that the coupling of water loss and solute gain is of utmost importance for a reliable estimation of mass transfer properties during OD.
JOURNAL OF FOOD ENGINEERING
(2022)
Review
Food Science & Technology
Raul Avila-Sosa, Guadalupe Virginia Nevarez-Moorillon, Carlos Enrique Ochoa-Velasco, Addi Rhode Navarro-Cruz, Paola Hernandez-Carranza, Teresa Soledad Cid-Perez
Summary: This review evaluates the main bioactive compounds of saffron and their relationship with its commercial quality. Saffron's commercial value is determined by the presence of carotenoid derivatives, such as crocin, crocetin, picrocrocin, and safranal. Chemometric methods, coupled with chemical markers, can be used to detect adulterated samples and determine their concentrations. Geographical origin and harvest/postharvest characteristics can affect the chemical composition and concentration of compounds in saffron. Saffron's by-products also contain various chemical compounds that add to its value as an aromatic spice.
Article
Multidisciplinary Sciences
Orietta Segura-Badilla, Ashuin Kammar-Garcia, Jeyne Mosso-Vazquez, Raul Avila-Sosa Sanchez, Carlos Ochoa-Velasco, Paola Hernandez-Carranza, Addi Rhode Navarro-Cruz
Summary: This study aimed to utilize disinfected waste banana peels to create food products, reducing waste and recovering nutrients. The results showed that waste banana peel flour can be used as a substitute for wheat flour in bakery and pasta products. These products were well-accepted by consumers and showed increased fiber and fat content.
Article
Food Science & Technology
Itzel Yoali Hernandez-Montesinos, David Fernando Carreon-Delgado, Erik Ocaranza-Sanchez, Carlos Enrique Ochoa-Velasco, Angela Suarez-Jacobo, Carolina Ramirez-Lopez
Summary: This study evaluated the effects of two pretreatments (fermentation with Lactobacillus plantarum and heat processing) and two extraction solvents (70% ethanol and methanol) on the bioactivity of garlic peel extracts. The results showed that the pretreatments significantly increased the total phenolic and flavonoid content of the extracts, as well as their antioxidant and antimicrobial activities against food-spoilage strains. This study reveals an innovative approach to utilize garlic residues as a potential source of antioxidant and antimicrobial agents for food applications.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Plant Sciences
Paola Hernandez-Carranza, Raul Avila-Sosa, Obdulia Vera-Lopez, Addi R. Navarro-Cruz, Hector Ruiz-Espinosa, Irving I. Ruiz-Lopez, Carlos E. Ochoa-Velasco
Summary: Tomato, an important fruit worldwide, is affected by stress factors. Tomato plants respond to stress through hormone involvement and reduce oxidative damage caused by stress factors through the antioxidant system. However, the impact of endogenous and/or exogenous hormones on tomato secondary metabolism is still poorly understood.
Article
Food Science & Technology
Fatima Reyes-Jurado, Zyanya Barcena-Massberg, Nelly Ramirez-Corona, Aurelio Lopez-Malo, Enrique Palou
Summary: The antifungal activity of thyme essential oil in vapor-phase was tested against representative fungi in corn tortillas. The major components of the oil were linalool, thymol, and p-cymene. Thyme essential oil effectively prevented or delayed the growth of contaminating molds on corn tortillas.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
