A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction

(2016) Toshana L. Foster et al.   Cell Host & Microbe

Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a

(2016) Maximilian Riess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alphavirus Restriction by IFITM Proteins

(2016) Stuart Weston et al.   TRAFFIC

SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells

(2016) Serena Bonifati et al.   VIROLOGY

H11/HSPB8 Restricts HIV-2 Vpx to Restore the Anti-Viral Activity of SAMHD1

(2016) Ayumi Kudoh et al.   Frontiers in Microbiology

Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunity

(2016) Shen Yang et al.   Scientific Reports

The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry

(2015) Sumudu K. Narayana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain

(2015) Junpeng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of SAMHD1 by Vpx Is Independent of Uncoating

(2015) Paula Jáuregui et al.   JOURNAL OF VIROLOGY

Can HIV-1 Entry Sites Be Deduced by Comparing Bulk Endocytosis to Functional Readouts for Viral Fusion?

(2015) Mariana Marin et al.   JOURNAL OF VIROLOGY

Reply to “Can HIV-1 Entry Sites Be Deduced by Comparing Bulk Endocytosis to Functional Readouts for Viral Fusion?”

(2015) Nikolas Herold et al.   JOURNAL OF VIROLOGY

IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein

(2015) Jingyou Yu et al.   Cell Reports

IFITM Proteins Incorporated into HIV-1 Virions Impair Viral Fusion and Spread

(2014) Alex A. Compton et al.   Cell Host & Microbe

HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

(2014) N. Herold et al.   JOURNAL OF VIROLOGY

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

(2014) Kevin Tartour et al.   Retrovirology

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

(2014) Charles C. Bailey et al.   Annual Review of Virology

Effect of Culture Conditions on the Phenotype of THP-1 Monocyte Cell Line

(2013) Paulomi B. Aldo et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry

(2013) Samad Amini-Bavil-Olyaee et al.   Cell Host & Microbe

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply

(2013) Loic Dragin et al.   Retrovirology

Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1

(2013) Alexandra Cribier et al.   Cell Reports

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1

(2013) Oliver I. Fregoso et al.   PLoS Pathogens

IFITM Proteins Restrict Viral Membrane Hemifusion

(2013) Kun Li et al.   PLoS Pathogens

The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

(2012) Efrem S. Lim et al.   Cell Host & Microbe

HIV/Simian Immunodeficiency Virus (SIV) Accessory Virulence Factor Vpx Loads the Host Cell Restriction Factor SAMHD1 onto the E3 Ubiquitin Ligase Complex CRL4DCAF1

(2012) Jinwoo Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

Quantification of Reverse Transcriptase Activity by Real-Time PCR as a Fast and Accurate Method for Titration of HIV, Lenti- and Retroviral Vectors

(2012) Jolien Vermeire et al.   PLoS One

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells

(2012) Benjamin Descours et al.   Retrovirology

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

(2010) J. M. Weidner et al.   JOURNAL OF VIROLOGY

The IFITM Proteins Inhibit HIV-1 Infection

(2010) J. Lu et al.   JOURNAL OF VIROLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

The HIV Envelope but Not VSV Glycoprotein Is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells

(2009) Dongyang Yu et al.   PLoS Pathogens

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors

(2008) G Berger et al.   GENE THERAPY

VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability

(2008) Sonia Brun et al.   Retrovirology

Primate Lentiviral Vpx Commandeers DDB1 to Counteract a Macrophage Restriction

(2008) Natalia Sharova et al.   PLoS Pathogens