Letter
Medicine, General & Internal
Olivier C. Manintveld, Stefan Roest, Yannick J. H. J. Taverne
Summary: In the study by Suverein et al., the use of extracorporeal cardiopulmonary resuscitation (CPR) in patients with refractory out-of-hospital cardiac arrest was examined. The results showed similar survival rates with a favorable neurologic outcome between extracorporeal CPR and conventional CPR. This raises questions about the role of extracorporeal CPR as an adjunct to conventional CPR.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Martin Jonsson, Ellinor Berglund, Enrico Baldi, Maria Luce Caputo, Angelo Auricchio, Marieke T. Blom, Hanno L. Tan, Remy Stieglis, Linn Andelius, Fredrik Folke, Jacob Hollenberg, Leif Svensson, Mattias Ringh, ESCAPE NET Investigators
Summary: Activation of a volunteer responder system in cases of out-of-hospital cardiac arrest (OHCA) was associated with higher rates of bystander CPR, bystander defibrillation, and 30-day survival compared to no system activation. A randomized controlled trial is necessary to determine the causal effect of volunteer responder systems.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Multidisciplinary Sciences
Jun Nakajima, Yusuke Sawada, Yuta Isshiki, Yumi Ichikawa, Kazunori Fukushima, Yuto Aramaki, Kiyohiro Oshima
Summary: The prehospital administered dosage of epinephrine influences the plasma levels of Ep, but does not contribute to the plasma levels of norepinephrine (Nep), dopamine (DOA) and vasopressin (ADH) in patients with out-of-hospital cardiac arrest (OHCA).
Article
Critical Care Medicine
Gillian Hutton, Takahisa Kawano, Frank X. Scheuermeyer, Ashish R. Panchal, Michael Asamoah-Boaheng, Jim Christenson, Brian Grunau
Summary: The study found significant regional differences in the rationale and interval until termination of resuscitation in out-of-hospital cardiac arrest cases. Cases terminated due to obvious death or do-not-resuscitate orders/verbal directives often receive similar durations of resuscitation as survivors.
Article
Medicine, General & Internal
Josef Dankiewicz, Tobias Cronberg, Gisela Lilja, Janus C. Jakobsen, Helena Levin, Susann Ullen, Christian Rylander, Matt P. Wise, Mauro Oddo, Alain Cariou, Jan Belohlavek, Jan Hovdenes, Manoj Saxena, Hans Kirkegaard, Paul J. Young, Paolo Pelosi, Christian Storm, Fabio S. Taccone, Michael Joannidis, Clifton Callaway, Glenn M. Eastwood, Matt P. G. Morgan, Per Nordberg, David Erlinge, Alistair D. Nichol, Michelle S. Chew, Jacob Hollenberg, Matthew Thomas, Jeremy Bewley, Katie Sweet, Anders M. Grejs, Steffen Christensen, Matthias Haenggi, Anja Levis, Andreas Lundin, Joachim During, Simon Schmidbauer, Thomas R. Keeble, Grigoris V. Karamasis, Claudia Schrag, Edith Faessler, Ondrej Smid, Michal Otahal, Marco Maggiorini, Pedro D. Wendel Garcia, Paul Jaubert, Jade M. Cole, Miroslav Solar, Ola Borgquist, Christoph Leithner, Samia Abed-Maillard, Leanlove Navarra, Martin Annborn, Johan Unden, Iole Brunetti, Akil Awad, Peter McGuigan, Roy Bjorkholt Olsen, Tiziano Cassina, Philippe Vignon, Halvor Langeland, Theis Lange, Hans Friberg, Niklas Nielsen
Summary: A randomized trial comparing hypothermia and normothermia treatment after out-of-hospital cardiac arrest showed no significant differences in death or functional outcomes at 6 months. The hypothermia group had a higher incidence of arrhythmia resulting in hemodynamic compromise compared to the normothermia group.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Critical Care Medicine
Thomas Rea, Peter J. Kudenchuk, Michael R. Sayre, Ann Doll, Mickey Eisenberg
Summary: Advances in resuscitation following out-of-hospital cardiac arrest offer an opportunity to improve public health. Through scientific progress and efficient emergency systems, early recognition, CPR, and defibrillation are key components in improving treatment outcomes.
Review
Cardiac & Cardiovascular Systems
Katie N. Dainty, Brianna Colquitt, Farhan Bhanji, Elizabeth A. Hunt, Tiffany Jefkins, Marion Leary, Joseph P. Ornato, Robert A. Swor, Ashish Panchal
Summary: Bystander cardiopulmonary resuscitation (CPR) is crucial for increasing survival rates in out-of-hospital cardiac arrest cases. However, the percentage of individuals receiving bystander CPR globally is currently low, at only 35% to 40%. This scientific statement aims to summarize the latest evidence on the training, response, and residual impact of witnessing out-of-hospital cardiac arrest among lay responders. The statement highlights the importance of addressing barriers to responding, experiences of performing CPR, the use of automated external defibrillators, the impact of dispatcher-assisted CPR, and the potential for psychological consequences after the event. By focusing on the experiences of actual responders, it is possible to develop more context-specific training that addresses factors such as performing CPR on a family member, dispelling myths, and acknowledging the potential for psychological sequelae.
Article
Medicine, General & Internal
Roberto Primi, Sara Bendotti, Alessia Currao, Giuseppe Maria Sechi, Gianluca Marconi, Greta Pamploni, Gianluca Panni, Davide Sgotti, Ettore Zorzi, Marco Cazzaniga, Umberto Piccolo, Daniele Bussi, Simone Ruggeri, Fabio Facchin, Edoardo Soffiato, Vincenza Ronchi, Enrico Contri, Paola Centineo, Francesca Reali, Luigi Sfolcini, Francesca Romana Gentile, Enrico Baldi, Sara Compagnoni, Federico Quilico, Luca Vicini Scajola, Clara Lopiano, Alessandro Fasolino, Simone Savastano, Lombardia CARe Researchers
Summary: This study compared the effectiveness of mechanical and manual CPR in Out-of-Hospital Cardiac Arrest (OHCA) patients. Mechanical chest compressors could increase the probability of return of spontaneous circulation (ROSC) and 30-day survival, with different devices having different performances. The load-distributing-band device was the only one that positively affected 30-day survival.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Emergency Medicine
Kwok Fung Sun, Kin Ming Poon, Chun Tat Lui, Kwok Leung Tsui
Summary: A clinical prediction rule of termination of resuscitation for out-of-hospital cardiac arrest patients with pre-hospital defibrillation was derived from a retrospective multicenter cohort study. The rule includes EMS call to ED time and ETCO2 level as independent predictors for predicting death before ED arrival. When both criteria are met, there is a high specificity and positive predictive value for predicting death before ED arrival in OHCA patients with pre-hospital defibrillation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Critical Care Medicine
Tasuku Matsuyama, Bon Ohta, Kosuke Kiyohara, Tetsuhisa Kitamura
Summary: This study aimed to assess the association between cardiopulmonary resuscitation (CPR)duration and outcomes after out-of-hospital cardiac arrest (OHCA). The results demonstrated that the probability of favorable neurological outcomes decreased with CPR duration. The impact of CPR duration may be influenced by each patient's clinical features.
Article
Critical Care Medicine
Deborah Wagner, S. L. Kronick, H. Nawer, J. A. Cranford, S. M. Bradley, R. W. Neumar
Summary: This retrospective cohort study compared the use of amiodarone and lidocaine in adult patients with in-hospital cardiac arrest from VT/VF. The study found that compared to amiodarone, lidocaine therapy was associated with significantly higher rates of ROSC, 24 h survival, survival to hospital discharge, and favorable neurologic outcome.
Article
Public, Environmental & Occupational Health
Theo Walter Jensen, Stig Nikolaj Blomberg, Fredrik Folke, Soren Mikkelsen, Martin Rostgaard-Knudsen, Palle Juelsgaard, Erika Frishknecht Christensen, Christian Torp-Pedersen, Freddy Lippert, Helle Collatz Christensen
Summary: The Danish Cardiac Arrest Registry aims to monitor and evaluate the quality of prehospital cardiac arrest treatment and facilitate research. It records descriptive and qualitative variables related to out-of-hospital cardiac arrest and provides important data for assessing treatment protocols and patient outcomes. The registry is one of the oldest and most comprehensive national clinical registries in Denmark, playing a crucial role in improving the care for patients suffering from out-of-hospital cardiac arrest.
CLINICAL EPIDEMIOLOGY
(2022)
Article
Critical Care Medicine
Tatsuma Fukuda, Naoko Ohashi-Fukuda, Ryota Inokuchi, Yutaka Kondo, Takayuki Taira, Ichiro Kukita
Summary: This study analyzed nationwide registry data in Japan and found that delayed epinephrine administration was associated with lower 1-month neurologically favorable survival among out-of-hospital cardiac arrest patients.
Article
Critical Care Medicine
Guillaume Debaty, Lionel Lamhaut, Romain Aubert, Mathilde Nicol, Caroline Sanchez, Olivier Chavanon, Pierre Bouzat, Michel Durand, Gerald Vanzetto, Alice Hutin, Deborah Jaeger, Tahar Chouihed, Jose Labarere
Summary: Analyzing the data from three cohort studies, this research examined the prevalence and prognostic value of signs of life before or throughout conventional CPR in individuals undergoing ECPR for refractory OHCA. The study found that individuals with any sign of life, pupillary light reaction, or increased level of consciousness had higher odds of 30-day survival with favorable neurological outcome. The lack of any sign of life might indicate patients without shockable cardiac rhythm could be excluded from receiving ECPR.
Article
Cardiac & Cardiovascular Systems
Anne Juul Grabmayr, Fredrik Folke, Mads Christian Tofte Gregers, Louise Kollander, Nanna Bo, Linn Andelius, Theo Walter Jensen, Florian Ettl, Mario Krammel, Patrick Sulzgruber, Konstantin A. Krychtiuk, Christian Torp-Pedersen, Annette Kjaer Ersboll, Carolina Malta Hansen
Summary: This study assessed interventions before ambulance arrival and survival for public out-of-hospital cardiac arrest (OHCA) patients in residential neighborhoods. The results showed that there were fewer resuscitative efforts before ambulance arrival and lower survival rates for OHCA patients in residential neighborhoods compared to nonresidential areas. Therefore, targeted efforts to improve early cardiopulmonary resuscitation (CPR) and defibrillation for public OHCA patients in residential neighborhoods are needed.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Emergency Medicine
Seo Young Kim, Sun Young Lee, Tae Han Kim, Sang Do Shin, Kyoung Jun Song, Jeong Ho Park
Summary: This study found that OHCA occurring in private housing and nursing facilities were less likely to have immediate EMS activation after collapse compared to public places. Public education is needed to increase awareness of the importance of prompt EMS activation.
EMERGENCY MEDICINE JOURNAL
(2022)
Article
Public, Environmental & Occupational Health
Justin Rodgers, Hwa-Young Lee, Rockli Kim, Nachiket Mor, S. V. Subramanian
Summary: The overall prevalence of caesarean delivery in India in 2016 was 19.3%, with most geographic variation attributable to states (44%), communities (32%), and districts (24%). After adjusting for all risk factors, the variance explained was 44%, 52% and 46% for states, districts, and communities, respectively. In public facilities, individual risk factors accounted for a larger proportion of variation compared to private facilities.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Sun Young Lee, Young Sun Ro, Joo Jeong, Sang Do Shin, Sungwoo Moon
Summary: This study investigated the impact of the COVID-19 pandemic on psychiatric patients visiting emergency departments. It found that the incidence of psychiatric self-harm and the proportion of psychiatric patients visiting emergency departments increased during the pandemic.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Mi Jin Lee, Woo Young Nho, Haewon Jung, Jae Wan Cho, Jun Seok Seo, Hyung Min Lee, Kwang Hyun Cho, Yun Jeong Kim, Jong Kun Kim
Summary: Approximately one-third of EM residents in South Korea report depression and sleep-wake problems, with female residents showing a higher risk than male residents. Difficulty in trading the shift schedule and frequent night shifts are associated with depression.
ANNALS OF MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Hwa-Young Lee, Nam-Hee Kim, Ichiro Kawachi
Summary: Although people with serious major diseases are more likely to have poor oral health, financial constraints lead to deferred treatment. The South Korean government introduced benefit expansion policies for major disease categories and dental prosthetic services. The study found that the benefit expansion did not significantly affect dental service utilization for major disease patients, but had a larger effect on dental prosthetic service utilization.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Environmental Sciences
Jiyun Jung, Jae Yoon Park, Woojae Myung, Jun-Young Lee, Hyunwoong Ko, Hyewon Lee
Summary: Higher levels of residential greenness are associated with a decreased risk of Parkinson's disease incidence, particularly in individuals over 50 years old, females, overweight/obese individuals, non-urban residents, non-smokers, alcoholics, and those with comorbidities.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Geriatrics & Gerontology
Yo Han Han, Shin Hye Yoo, Sun Young Lee, In Young Hwang, Kyae Hyung Kim, Belong Cho, Min Sun Kim, Wonho Choi, Yejin Kim
Summary: This study investigated the needs and characteristics of patients with cancer and neurologic disorders requiring home-based medical care. The study found that homebound patients usually require support and management in activities such as respiratory, feeding, and urinary system. Patients with progressive neurologic disorders are more dependent on medical care, and long-term users of home-based medical care mostly need feeding and respiratory support.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Medicine, General & Internal
Seung Yeon Lee, Kyoung Jun Song, Chun Soo Lim, Young Jun Chai, Sun Young Lee, Stephen Gyung Won Lee
Summary: This study analyzed the risk factors associated with the transfer of mild COVID-19 patients from a community treatment center to a hospital, and found that older age and presentation in autumn were significantly associated with increased odds of hospital transfer. The findings highlight the importance of thorough assessment and close monitoring of COVID-19 patients, as well as timely allocation of appropriate resources to high-risk groups.
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION
(2022)
Article
Emergency Medicine
Yonghoon Jang, Tae Han Kim, Sun Young Lee, Young Sun Ro, Ki Jeong Hong, Kyoung Jun Song, Sang Do Shin
Summary: This study analyzed the association between transport time interval (TTI) and survival rate and neurologic outcome in out-of-hospital cardiac arrest (OHCA) patients without return of spontaneous circulation (ROSC). The study found that as TTI increased, the rate of good neurologic recovery decreased. However, when advanced airway management was performed by emergency medical service providers, the negative effect of prolonged TTI on neurological outcome was insignificant.
CLINICAL AND EXPERIMENTAL EMERGENCY MEDICINE
(2022)
Article
Emergency Medicine
Sun Young Lee, Jeong Ho Park, Young Ho Choi, Jungah Lee, Young Sun Ro, Ki Jeong Hong, Kyoung Jun Song, Sang Do Shin
Summary: This study found that individual-level socioeconomic status is associated with the occurrence of out-of-hospital cardiac arrest (OHCA). Low individual-level socioeconomic status is linked to a higher probability of OHCA occurrence. The disparity in OHCA occurrence due to individual-level socioeconomic status appears to be greater in males and in young and middle-aged adults. Efforts are needed to reduce socioeconomic disparities in the occurrence of OHCA.
ACADEMIC EMERGENCY MEDICINE
(2022)
Review
Oncology
Tomotaka Ugai, Naoko Sasamoto, Hwa-Young Lee, Mariko Ando, Mingyang Song, Rulla M. Tamimi, Ichiro Kawachi, Peter T. Campbell, Edward L. Giovannucci, Elisabete Weiderpass, Timothy R. Rebbeck, Shuji Ogino
Summary: The incidence of early-onset cancers (diagnosed in individuals <50 years of age) has increased in many countries in recent decades. This increase is probably due to greater use of screening programs and changing patterns in early-life exposures. Evidence suggests that risk factor exposures in early life and young adulthood play an etiological role in the development of these cancers.
NATURE REVIEWS CLINICAL ONCOLOGY
(2022)
Article
Emergency Medicine
Soo In Lee, Saee Byel Kang, Sun Young Lee, Dong Sun Choi
Summary: The number and distribution of isolation rooms in different regions of Korea vary, and the distribution of isolation beds in emergency departments may affect ambulance travel time and burden during the COVID-19 pandemic. This study found that in regions with more isolation rooms per population, the impact of COVID-19 on ambulance call-to-scene time and call-to-return time was smaller.
CLINICAL AND EXPERIMENTAL EMERGENCY MEDICINE
(2023)
Article
Clinical Neurology
Jung-In Ko, Seok-Jin Choi, Shin Hye Yoo, Belong Cho, Min Sun Kim, Kyae Hyung Kim, Sun Young Lee
Summary: This study investigated the characteristics of ALS patients visiting the emergency department (ED). The results showed that 41.8% of patients arrived by ambulance and 27.7% spent more than 9 hours in the ED. After ED treatment, 57.4% were hospitalized, with 19.3% admitted to the intensive care unit (ICU) and 5.4% dying in the hospital. The primary reasons for ALS-related ED visits were dyspnea (35.2%), feeding tube problems (10.1%), fever (7.8%), and mental status changes (3.6%).
Article
Health Care Sciences & Services
In Young Hwang, Yohan Han, Min Sun Kim, Kyae Hyung Kim, Belong Cho, Wonho Choi, Yejin Kim, Shin Hye Yoo, Sun Young Lee
Summary: Respecting patients' preference for place of care is crucial in advance care planning for advanced cancer. This retrospective study in South Korea investigated adult cancer patients referred to a palliative care consultation team, recording their preference for place of care and demographic/clinical factors. Among the 891 patients referred, 23.6% preferred home discharge and only 53.8% of them were actually discharged home. Female patients had higher home discharge rates, while those with poor oral intake or dyspnea had lower rates. Additionally, 32.8% of patients discharged home had unintended hospital visits within 2 months. Individualized care planning considering relevant factors is necessary to meet patients' preferences for end-of-life care.
Article
Medicine, General & Internal
Sun Young Lee, Seung-sik Hwang, Jeong Ho Park, Kyoung Jun Song, Sang Do Shin
Summary: This study investigated the impact of the awareness time interval (ATI) on out-of-hospital cardiac arrest (OHCA) outcomes. The results showed that the effect of early bystander cardiopulmonary resuscitation (BCPR) on improving neurological outcomes decreased with longer ATI delay. Therefore, the importance of early recognition of OHCA and activation of emergency medical services (EMS) should be emphasized.
YONSEI MEDICAL JOURNAL
(2023)
