4.6 Article

Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting

Journal

REPRODUCTIVE BIOMEDICINE ONLINE
Volume 36, Issue 6, Pages 658-674

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.rbmo.2018.02.005

Keywords

Air quality; Infection control; Laboratory design; Quality management; Volatile organic compounds

Funding

  1. Upper Egypt Assisted Reproduction Conference 2017
  2. MRC [G0801057] Funding Source: UKRI

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This proceedings report presents the outcomes from an international Expert Meeting to establish a consensus on the recommended technical and operational requirements for air quality within modern assisted reproduction technology (ART) laboratories. Topics considered included design and construction of the facility, as well as its heating, ventilation and air conditioning system; control of particulates, micro-organisms (bacteria, fungi and viruses) and volatile organic compounds (VOCs) within critical areas; safe cleaning practices; operational practices to optimize air quality while minimizing physicochemical risks to gametes and embryos (temperature control versus air flow); and appropriate infection-control practices that minimize exposure to VOC. More than 50 consensus points were established under the general headings of assessing site suitability, basic design criteria for new construction, and laboratory commissioning and ongoing VOC management. These consensus points should be considered as aspirational benchmarks for existing ART laboratories, and as guidelines for the construction of new ART laboratories. (C) 2018 The Authors. Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd.

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