Lappaconitine, a C18-diterpenoid alkaloid, exhibits antihypersensitivity in chronic pain through stimulation of spinal dynorphin A expression

Liposome-encapsulated clodronate specifically depletes spinal microglia and reduces initial neuropathic pain

(2018) Yi-Rui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Concurrent bullatine A enhances morphine antinociception and inhibits morphine antinociceptive tolerance by indirect activation of spinal κ-opioid receptors

(2017) Qian Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

p38 β Mitogen-Activated Protein Kinase Signaling Mediates Exenatide-Stimulated Microglial β -Endorphin Expression

(2017) Hai-Yun Wu et al.   MOLECULAR PHARMACOLOGY

Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition

(2017) Yong-Xiang Wang et al.   Scientific Reports

Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin

(2017) Teng-Fei Li et al.   Scientific Reports

Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models

(2016) Qian Huang et al.   Journal of Neuroinflammation

Aconitum-Derived Bulleyaconitine A Exhibits Antihypersensitivity Through Direct Stimulating Dynorphin A Expression in Spinal Microglia

(2016) Teng-Fei Li et al.   JOURNAL OF PAIN

Microglial Cells as a Link between Cannabinoids and the Immune Hypothesis of Psychiatric Disorders

(2016) Sabrina F. Lisboa et al.   Frontiers in Neurology

Nanostructured lipid carriers for percutaneous administration of alkaloids isolated from Aconitum sinomontanum

(2015) Teng Guo et al.   JOURNAL OF NANOBIOTECHNOLOGY

Analgesic effects of lappaconitine in leukemia bone pain in a mouse model

(2015) Xiao-Cui Zhu et al.   PeerJ

Lamiophlomis rotata, an Orally Available Tibetan Herbal Painkiller, Specifically Reduces Pain Hypersensitivity States through the Activation of Spinal Glucagon-like Peptide-1 Receptors

(2014) Bin Zhu et al.   ANESTHESIOLOGY

The non-peptide GLP-1 receptor agonist WB4-24 blocks inflammatory nociception by stimulating β-endorphin release from spinal microglia

(2014) Hui Fan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of Spinal Glucagon-Like Peptide-1 Receptors Specifically Suppresses Pain Hypersensitivity

(2014) N. Gong et al.   JOURNAL OF NEUROSCIENCE

Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors

(2014) Nian Gong et al.   NEUROPHARMACOLOGY

Pain-Related Depression of the Mesolimbic Dopamine System in Rats: Expression, Blockade by Analgesics and Role of Endogenous κ-opioids

(2013) Michael D Leitl et al.   NEUROPSYCHOPHARMACOLOGY

Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal α3 glycine receptors

(2013) Jing-Yang Zhang et al.   PAIN

Contributions of spinal d-amino acid oxidase to bone cancer pain

(2012) Jin-Lu Huang et al.   AMINO ACIDS

Glia as a Link between Neuroinflammation and Neuropathic Pain

(2012) Mithilesh Kumar Jha et al.   Immune Network

d -Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain

(2011) Jin-Miao Lu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of lappaconitine on neuropathic pain mediated by P2X3 receptor in rat dorsal root ganglion

(2011) Shan Ou et al.   NEUROCHEMISTRY INTERNATIONAL

Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats

(2011) Tomas Drabek et al.   RESUSCITATION

Murine Kupffer Cells Are Protective in Total Hepatic Ischemia/Reperfusion Injury with Bowel Congestion through IL-10

(2010) J. D. Ellett et al.   JOURNAL OF IMMUNOLOGY

Structure–Analgesic Activity Relationship Studies on the C18- and C19-Diterpenoid Alkaloids

(2009) Jian-Li Wang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

X-ray structure analysis of lappaconitine

(2009) Wenxiu Sun et al.   NATURAL PRODUCT RESEARCH

Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain

(2007) Stefania Echeverry et al.   PAIN