Therapeutic role of rifampicin in Alzheimer's disease

Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers

(2016) Tomohiro Umeda et al.   BRAIN

A Role for P-Glycoprotein in Clearance of Alzheimer Amyloid ? -Peptide from the Brain

(2016) Wei Wang et al.   Current Alzheimer Research

Exposure of LS-180 Cells to Drugs of Diverse Physicochemical and Therapeutic Properties Up-regulates P-glycoprotein Expression and Activity

(2016) Alaa H Abuznait et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Memory recuperative potential of rifampicin in aluminum chloride-induced dementia: Role of pregnane X receptors

(2015) P. Kaur et al.   NEUROSCIENCE

RIFAMPICIN: An antibiotic with brain protective function

(2014) Burak Yulug et al.   BRAIN RESEARCH BULLETIN

Activity of P-Glycoprotein, a  -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease

(2014) A. K. Deo et al.   JOURNAL OF NUCLEAR MEDICINE

Efficacy and safety of rifampicin for multiple system atrophy: a randomised, double-blind, placebo-controlled trial

(2014) Phillip A Low et al.   LANCET NEUROLOGY

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

(2014) Takahisa Kanekiyo et al.   Frontiers in Aging Neuroscience

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Antibiotics acting as neuroprotectants via mechanisms independent of their anti-infective activities

(2013) Matthew L. Stock et al.   NEUROPHARMACOLOGY

A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer's disease: the DARAD trial

(2012) D. William Molloy et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Rifampicin and Parkinson’s disease

(2012) Wei Bi et al.   NEUROLOGICAL SCIENCES

Rifampicin inhibits microglial inflammation and improves neuron survival against inflammation

(2011) Wei Bi et al.   BRAIN RESEARCH

Insights into Alzheimer disease pathogenesis from studies in transgenic animal models

(2011) Evelin L. Schaeffer et al.   Clinics

Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease

(2011) Alaa H. Abuznait et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Animal models of amyloid-β-related pathologies in Alzheimer’s disease

(2010) Ola Philipson et al.   FEBS Journal

Rifampicin Inhibits the LPS-induced Expression of Toll-like Receptor 2 via the Suppression of NF-κB DNA-binding Activity in RAW 264.7 Cells

(2010) Seong Keun Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-  in a Mouse Model of Alzheimer's Disease

(2010) A. M. S. Hartz et al.   MOLECULAR PHARMACOLOGY

Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5

(2010) Marianne Renner et al.   NEURON

Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption

(2009) Wei-Qin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rifampicin reduces α-synuclein in a transgenic mouse model of multiple system atrophy

(2009) Kiren Ubhi et al.   NEUROREPORT

Rifampicin Does Not Prevent Amyloid Fibril Formation by Human Islet Amyloid Polypeptide but Does Inhibit Fibril Thioflavin-T Interactions: Implications for Mechanistic Studies of β-Cell Death†

(2008) Fanling Meng et al.   BIOCHEMISTRY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Inhibition of Amyloid Fibrillization of Hen Egg-White Lysozymes by Rifampicin and p-Benzoquinone

(2007) Valerie H. Lieu et al.   BIOTECHNOLOGY PROGRESS