Inverse enzyme isotope effects in human purine nucleoside phosphorylase with heavy asparagine labels
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inverse enzyme isotope effects in human purine nucleoside phosphorylase with heavy asparagine labels
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 27, Pages E6209-E6216
Publisher
Proceedings of the National Academy of Sciences
Online
2018-06-19
DOI
10.1073/pnas.1805416115
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Protein Mass Effects on Formate Dehydrogenase
- (2017) Chethya Ranasinghe et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic-site design for inverse heavy-enzyme isotope effects in human purine nucleoside phosphorylase
- (2017) Rajesh K. Harijan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Origin of Enzymatic Kinetic Isotope Effects in Human Purine Nucleoside Phosphorylase
- (2017) M. Roca et al. ACS Catalysis
- Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics
- (2016) Ioanna Zoi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Untangling Heavy Protein and Cofactor Isotope Effects on Enzyme-Catalyzed Hydride Transfer
- (2016) James E. Longbotham et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Treatment of hyperuricemia in gout: current therapeutic options, latest developments and clinical implications
- (2016) Sebastian E. Sattui et al. Therapeutic Advances in Musculoskeletal Disease
- Practical and conceptual path sampling issues
- (2015) P. G. Bolhuis et al. European Physical Journal-Special Topics
- Isotope-specific and amino acid-specific heavy atom substitutions alter barrier crossing in human purine nucleoside phosphorylase
- (2015) Javier Suarez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Dynamics in Enzyme Catalysis: Substantial versus Semantic Controversies
- (2014) Amnon Kohen ACCOUNTS OF CHEMICAL RESEARCH
- Final results of a multicenter phase II study of the purine nucleoside phosphorylase (PNP) inhibitor forodesine in patients with advanced cutaneous t-cell lymphomas (CTCL) (Mycosis fungoides and Sezary syndrome)
- (2014) R. Dummer et al. ANNALS OF ONCOLOGY
- Catalytic Site Conformations in Human PNP by 19F-NMR and Crystallography
- (2013) Javier Suarez et al. CHEMISTRY & BIOLOGY
- Mass Modulation of Protein Dynamics Associated with Barrier Crossing in Purine Nucleoside Phosphorylase
- (2012) Dimitri Antoniou et al. Journal of Physical Chemistry Letters
- Arsenate and Phosphate as Nucleophiles at the Transition States of Human Purine Nucleoside Phosphorylase
- (2011) Rafael G. Silva et al. BIOCHEMISTRY
- Flexibility, Diversity, and Cooperativity: Pillars of Enzyme Catalysis
- (2011) Gordon G. Hammes et al. BIOCHEMISTRY
- Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme
- (2011) R. G. Silva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Four generations of transition-state analogues for human purine nucleoside phosphorylase
- (2010) M.-C. Ho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loop-Tryptophan Human Purine Nucleoside Phosphorylase Reveals Submillisecond Protein Dynamics†
- (2009) Mahmoud Ghanem et al. BIOCHEMISTRY
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Enzymatic transition states and dynamic motion in barrier crossing
- (2009) Steven D Schwartz et al. Nature Chemical Biology
- Tryptophan-Free Human PNP Reveals Catalytic Site Interactions†
- (2008) Mahmoud Ghanem et al. BIOCHEMISTRY
- Atomic detail of chemical transformation at the transition state of an enzymatic reaction
- (2008) S. Saen-oon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More