Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis

E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells

(2018) Hyun-Wook Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249

(2017) Mao-Wen Weng et al.   Oncotarget

Mutational signatures associated with tobacco smoking in human cancer

(2016) L. B. Alexandrov et al.   SCIENCE

Current Cigarette Smoking Among Adults — United States, 2005–2015

(2016) Ahmed Jamal et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer

(2015) Bhagavatula Moorthy et al.   TOXICOLOGICAL SCIENCES

Cigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation

(2015) Hyun-Wook Lee et al.   Oncotarget

Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells

(2015) Hyun-Wook Lee et al.   Oncotarget

Abstract 120: Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies.

(2014) Jishen Pan et al.   CANCER RESEARCH

Inhibition of human cytochrome P450 2E1 and 2A6 by aldehydes: Structure and activity relationships

(2014) Suneel K. Kandagatla et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Variations in CYP isoforms and bladder cancer: A superfamily paradigm

(2013) Monica Sankhwar et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Effect of CpG methylation at different sequence context on acrolein- and BPDE-DNA binding and mutagenesis

(2012) Hsiang-Tsui Wang et al.   CARCINOGENESIS

Effect of Carcinogenic Acrolein on DNA Repair and Mutagenic Susceptibility

(2012) Hsiang-Tsui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Green tea and prevention of esophageal and lung cancers

(2011) Jian-Min Yuan   MOLECULAR NUTRITION & FOOD RESEARCH

Acrolein induced DNA damage, mutagenicity and effect on DNA repair

(2011) Moon-shong Tang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Atherosclerosis lesion progression during inhalation exposure to environmental tobacco smoke: A comparison to concentrated ambient air fine particles exposure

(2010) Lung Chi Chen et al.   INHALATION TOXICOLOGY

Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers

(2010) Lei Yu et al.   INTERNATIONAL JOURNAL OF CANCER

DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry

(2009) Hong Zhao et al.   CYTOMETRY PART A

Levels of Tobacco-Specific Nitrosamines and Polycyclic Aromatic Hydrocarbons in Mainstream Smoke from Different Tobacco Varieties

(2008) Y. S. Ding et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION