Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3

Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

(2017) Max-Hinderk Schuler et al.   MOLECULAR BIOLOGY OF THE CELL

MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

(2017) T Ren et al.   ONCOGENE

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

The SIRT 3 Expression Profile is Associated with Pathological and Clinical Outcomes in Human Breast Cancer Patients

(2014) Shaozhong He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1

(2014) S M Jeong et al.   ONCOGENE

Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration

(2014) Leonithas I. Volakis et al.   PLoS One

A Mitochondrial Switch Promotes Tumor Metastasis

(2014) Paolo E. Porporato et al.   Cell Reports

Mitochondrial Localization and the Persistent Migration of Epithelial Cancer cells

(2013) Salil P. Desai et al.   BIOPHYSICAL JOURNAL

An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization

(2013) Tsukasa Shibue et al.   CANCER CELL

BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

(2012) Seo-Kyung Lim et al.   CLINICAL & EXPERIMENTAL METASTASIS

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

(2012) Mei Rosa Ng et al.   JOURNAL OF CELL BIOLOGY

Redox regulation of cancer cell migration and invasion

(2012) Lalchhandami Tochhawng et al.   MITOCHONDRION

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Classifying collective cancer cell invasion

(2012) Peter Friedl et al.   NATURE CELL BIOLOGY

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

(2012) J Zhao et al.   ONCOGENE

Redox control of cell proliferation

(2012) Joyce Chiu et al.   TRENDS IN CELL BIOLOGY

The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like Protrusions

(2012) Tsukasa Shibue et al.   Cancer Discovery

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

(2011) Christos Hatzis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

(2011) E L Bell et al.   ONCOGENE

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics

(2010) M. Canel et al.   CANCER RESEARCH

Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility

(2010) C. Martinez-Rico et al.   JOURNAL OF CELL SCIENCE

Genomic Index of Sensitivity to Endocrine Therapy for Breast Cancer

(2010) W. Fraser Symmans et al.   JOURNAL OF CLINICAL ONCOLOGY

Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals

(2009) Xiang H.-F. Zhang et al.   CANCER CELL

Copy Number Alterations that Predict Metastatic Capability of Human Breast Cancer

(2009) Y. Zhang et al.   CANCER RESEARCH

ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

(2008) K. Ishikawa et al.   SCIENCE