News Feature: The quest to solve sepsis

Recognizing Sepsis as a Global Health Priority — A WHO Resolution

(2017) Konrad Reinhart et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis

(2017) Liuyang Wang et al.   Science Advances

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality

(2016) André Scherag et al.   EBioMedicine

Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

(2015) Afshin Zariri et al.   Expert Review of Vaccines

A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

(2015) Leo McHugh et al.   PLOS MEDICINE

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study

(2015) Anna Rautanen et al.   Lancet Respiratory Medicine

Host defense peptides: front-line immunomodulators

(2014) Sarah C. Mansour et al.   TRENDS IN IMMUNOLOGY

An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation

(2014) Olga M. Pena et al.   EBioMedicine

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

eptic shock and community-acquired pneumonia associated with etanercept therapy

(2011) C. Nuñez-Cornejo et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

(2011) O. M. Pena et al.   JOURNAL OF IMMUNOLOGY