Article
Neurosciences
Justin M. Fine, David J. -N. Maisson, Seng Bum Michael Yoo, Tyler V. Cash-Padgett, Maya Zhe Wang, Jan Zimmermann, Benjamin Y. Hayden
Summary: An important question in neuroeconomics is how the brain represents the value of offers in a way that allows for comparison while preserving the details that influence value. This study examined neuronal responses in male macaques and found that there was no overlap in neural coding between risky and safe options, even when the options had identical subjective values. However, these regions were linked through a linear transform of their encodings, allowing for comparison of different types of options.
JOURNAL OF NEUROSCIENCE
(2023)
Review
Anatomy & Morphology
Edmund T. Rolls
Summary: The orbitofrontal cortex and amygdala are involved in emotion and motivation, but the relationship between these functions is not clear. A unified theory of emotion and motivation is described, in which motivational states involve instrumental goal-directed actions for rewards or punishment avoidance, while emotional states are elicited by received or not received rewards or punishment. Recent evidence suggests that the orbitofrontal cortex is involved in reward value and depression, while the amygdala is implicated in brainstem-mediated responses to stimuli and not declarative emotion. The anterior cingulate cortex is involved in learning actions for rewards and provides goals for navigation, along with the orbitofrontal and ventromedial prefrontal cortex.
BRAIN STRUCTURE & FUNCTION
(2023)
Article
Neurosciences
Carlos Silva, Blake S. Porter, Kristin L. Hillman
Summary: Animals must continually assess effort and physiological states during tasks, with the ACC and anterior insular cortex implicated in cost-benefit decision-making. Contrary to predictions, stimulation of Cg1 did not increase persistence in the task, while stimulation of the anterior insula had little effect on effortful behavior.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Critical Care Medicine
Jeremy Hogeveen, Denicia F. Aragon, Kimberly Rogge-Obando, Richard A. Campbell, C. William Shuttleworth, Rebecca E. Avila-Rieger, Ronald A. Yeo, J. Kevin Wilson, Violet Fratzke, Emma Brandt, Jacqueline Story-Remer, Darbi Gill, Andrew R. Mayer, James F. Cavanagh, Davin K. Quinn
Summary: This study revealed a connection between apathy following traumatic brain injury (TBI) and alterations in motivational neural circuits, with different levels of apathy in TBI patients related to changes in brain region functional connectivity.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Neurosciences
Edmund T. Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Feng
Summary: The human orbitofrontal cortex, vmPFC, and anterior cingulate cortex play a crucial role in reward processing, emotion, and episodic memory. Effective connectivity between cortical regions and subcortical regions was measured in the human brain, revealing the complex network involved in these processes. This research enhances our understanding of the functional and neural connections in the brain.
Article
Neurosciences
Yue Hu, Marijn van Wingerden, Manuela Sellitto, Sandra Schable, Tobias Kalenscher
Summary: Demand theory was used to study how rats adjust their commodity selection based on budget constraints and price changes. The study found that anterior cingulate cortex (ACC) plays a crucial role in budget effects on demand elasticities, as ACC-lesioned animals failed to adapt to higher-order choice strategies after price and budget changes.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Giovana Benassi-Cezar, Isabela Miranda Carmona, Daniela Baptista-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza
Summary: The study found that cohabitation with a conspecific suffering from chronic pain affects the anxiety levels of mice, with changes in neuronal activation observed in the anterior cingulate and insular cortices. Injecting a synaptic blocker in these brain areas can reverse the anxiety-inducing effect caused by cohabitation with a conspecific in chronic pain.
Article
Multidisciplinary Sciences
Erkin Asutay, Daniel Vastfjall
Summary: This study uses a hierarchical Bayesian modeling approach to analyze data from a risky choice task and finds that recently encountered choice parameters shape affective experience and impact subsequent choice behavior. Self-reported arousal prior to choice is associated with increased loss aversion, risk aversion, and choice consistency, providing clear behavioral evidence for continuous affective modulation of subjective value computations during risky decision-making.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Atsushi Fujimoto, Elisabeth A. Murray, Peter H. Rudebeck
Summary: Decision-making and representations of arousal are closely related, with an optimal level of bodily arousal facilitating performance. The interactions between these processes at the level of single neurons and neural circuits remain unclear.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Yujiao Yang, Dong Chen, Jing Wang, Jie Wang, Zhaofen Yan, Qinqin Deng, Liping Zhang, Guoming Luan, Mengyang Wang, Tianfu Li
Summary: This study aimed to investigate the dynamic coupling between the anterior cingulate cortex (ACC) and anterior insular cortex (AIC) during seizures. The results showed that the functional connectivity and excitability between these two brain regions significantly increased at seizure onset. By analyzing the connectivity and excitability, the seizure-onset zone (SOZ) in ACC and AIC can be identified.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Editorial Material
Neurosciences
Benjamin Yost Hayden
Summary: The parcellation of the primate cerebral cortex into numbered regions, based on cytoarchitecture, has been helpful to understand cognition. However, these maps limit functional neuroanatomy and it is time to think more broadly in order to incorporate emergentist organization and interactional complexity into neuroscience.
JOURNAL OF COGNITIVE NEUROSCIENCE
(2023)
Article
Biology
Hanna Keren, Charles Zheng, David C. Jangraw, Katharine Chang, Aria Vitale, Robb B. Rutledge, Francisco Pereira, Dylan M. Nielson, Argyris Stringaris
Summary: The research suggests that early events have a stronger influence on reported mood than recent events. This has implications for the timing of events in experimental or clinical settings and points towards new directions for individualized mood interventions.
Article
Biology
Lilya Andrianova, Steliana Yanakieva, Gabriella Margetts-Smith, Shivali Kohli, Erica S. Brady, John P. Aggleton, Michael T. Craig
Summary: The connectivity and interplay between the prefrontal cortex and hippocampus are important for cognitive processes, but the existence of a direct glutamatergic projection from the anterior cingulate cortex to the hippocampus has been questioned. In this study, multiple methods were used to validate a recent finding of this projection, but no evidence of such a projection was found.
Article
Biochemistry & Molecular Biology
Anna Todeva-Radneva, Sevdalina Kandilarova, Rositsa Paunova, Drozdstoy Stoyanov, Tina Zdravkova, Ronald Sladky
Summary: This study aimed to explore possible differences in whole-brain functional connectivity in patients with major depressive disorder (MDD), bipolar disorder (BD), and healthy controls (HC). The results showed increased connectivity in certain brain regions in the BD group compared to the HC group, while the MDD group showed enhanced connectivity in different regions. These findings suggest that these connectivity patterns may serve as potential diagnostic biomarkers for MDD and BD.
Article
Neurosciences
Andy Schumann, Feliberto de la Cruz, Stefanie Koehler, Lisa Brotte, Karl-Juergen Baer
Summary: This study investigated the impact of an 8-week HRV-biofeedback intervention on functional brain connectivity in healthy subjects. The results showed that increased heart rate variability induced by HRV-biofeedback was accompanied by changes in functional brain connectivity during resting state, particularly in the VMPFC and other brain regions such as the insula, amygdala, and prefrontal regions. The findings suggest that HRV biofeedback can enhance brain connectivity and may have implications for stress and emotion regulation.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Psychology
Jessica A. Cooper, Darrell A. Worthy, W. Todd Maddox
COGNITIVE PSYCHOLOGY
(2015)
Article
Behavioral Sciences
Nathaniel J. Blanco, Bradley C. Love, Jessica A. Cooper, John E. McGeary, Valerie S. Knopik, W. Todd Maddox
NEUROBIOLOGY OF LEARNING AND MEMORY
(2015)
Article
Neurosciences
Darrell A. Worthy, Tyler Davis, Marissa A. Gorlick, Jessica A. Cooper, Akram Bakkour, Jeanette A. Mumford, Russell A. Poldrack, W. Todd Maddox
Article
Behavioral Sciences
Jessica A. Cooper, Marissa A. Gorlick, Taylor Denny, Darrell A. Worthy, Christopher G. Beevers, W. Todd Maddox
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
(2014)
Article
Behavioral Sciences
Darrell A. Worthy, Jessica A. Cooper, Kaileigh A. Byrne, Marissa A. Gorlick, W. Todd Maddox
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
(2014)
Review
Behavioral Sciences
Michael T. Treadway, Jessica A. Cooper, Andrew H. Miller
TRENDS IN COGNITIVE SCIENCES
(2019)
Article
Psychology, Biological
Shosuke Suzuki, Victoria M. Lawlor, Jessica A. Cooper, Amanda R. Arulpragasam, Michael T. Treadway
Summary: The study identified functionally segregated regions within the ventral striatum that separately encoded effort activation, movement initiation, and effort discounting of rewards using functional magnetic resonance imaging with a naturalistic maze-navigation paradigm. The results suggest that different regions of the ventral striatum are involved in encoding effort and value, raising important questions about interpreting reward signals in the context of effort demands.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Multidisciplinary Sciences
Jessica A. Cooper, Makiah R. Nuutinen, Victoria M. Lawlor, Brittany A. M. DeVries, Elyssa M. Barrick, Shabnam Hossein, Daniel J. Cole, Chelsea Leonard, Emma C. Hahn, Andrew P. Teer, Grant S. Shields, George M. Slavich, Dost Ongur, J. Eric Jensen, Fei Du, Diego A. Pizzagalli, Michael T. Treadway
Summary: The study found evidence of an adaptive mPFC glutamate response to stress in healthy adults, which is notably impaired in patients with major depression. Stress impacts glutamate function in the mPFC, and this disruption is significant in individuals with MDD.
NATURE COMMUNICATIONS
(2021)
Article
Psychology, Clinical
Jessica A. Cooper, Deanna M. Barch, L. Felice Reddy, William P. Horan, Michael F. Green, Michael T. Treadway
JOURNAL OF ABNORMAL PSYCHOLOGY
(2019)
Article
Behavioral Sciences
Jessica A. Cooper, Amanda R. Arulpragasam, Michael T. Treadway
CURRENT OPINION IN BEHAVIORAL SCIENCES
(2018)
Article
Neurosciences
Michael T. Treadway, Roee Admon, Amanda R. Arulpragasam, Malavika Mehta, Samuel Douglas, Gordana Vitaliano, David P. Olson, Jessica A. Cooper, Diego A. Pizzagalli
BIOLOGICAL PSYCHIATRY
(2017)
Article
Gerontology
Jessica A. Cooper, Nathaniel J. Blanco, W. Todd Maddox
PSYCHOLOGY AND AGING
(2017)
Article
Psychology, Developmental
Jessica A. Cooper, Darrell A. Worthy, W. Todd Maddox
AGING NEUROPSYCHOLOGY AND COGNITION
(2016)
Article
Psychology, Experimental
Jessica A. Cooper, Jessecae K. Marsh