Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 8, Pages 1697-1706
Publisher
Proceedings of the National Academy of Sciences
Online
2018-02-06
DOI
10.1073/pnas.1715554115
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies
- (2017) X Xiao et al. MOLECULAR PSYCHIATRY
- An atlas of human long non-coding RNAs with accurate 5′ ends
- (2017) Chung-Chau Hon et al. NATURE
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
- (2017) Rebecca Sims et al. NATURE GENETICS
- A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
- (2017) Kuan-lin Huang et al. NATURE NEUROSCIENCE
- Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity
- (2017) Joseph Webb et al. NEUROBIOLOGY OF AGING
- 11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project
- (2017) Na Cai et al. Scientific Data
- Association of the Single Nucleotide Polymorphisms in RUNX1, DYRK1A, and KCNJ15 with Blood Related Traits in Pigs
- (2016) Jae-Bong Lee et al. ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese
- (2016) Teng Jiang et al. NEUROBIOLOGY OF AGING
- ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis
- (2016) Eun Yong Kang et al. G3-Genes Genomes Genetics
- Lack of Genetic Association Between TREM2 and Alzheimer’s Disease in East Asian Population
- (2015) Man Huang et al. American Journal of Alzheimers Disease and Other Dementias
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. BIOPRESERVATION AND BIOBANKING
- GWAS of longitudinal amyloid accumulation on18F-florbetapir PET in Alzheimer’s disease implicates microglial activation geneIL1RAP
- (2015) Vijay K Ramanan et al. BRAIN
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Han Chinese patients with dopa-responsive dystonia exhibit a low frequency of exonic deletion in the GCH1 gene
- (2015) W.T. Shi et al. GENETICS AND MOLECULAR RESEARCH
- An efficient and scalable analysis framework for variant extraction and refinement from population-scale DNA sequence data
- (2015) Goo Jun et al. GENOME RESEARCH
- Polygenic determinants of Parkinson's disease in a Chinese population
- (2015) Ji-Feng Guo et al. NEUROBIOLOGY OF AGING
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. Biopreservation and Biobanking
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Parkinson’s disease in GTP cyclohydrolase 1 mutation carriers
- (2014) Niccolò E. Mencacci et al. BRAIN
- Validating GWAS-Identified Risk Loci for Alzheimer’s Disease in Han Chinese Populations
- (2014) Hui-Zhen Wang et al. MOLECULAR NEUROBIOLOGY
- Association study ofTREM2polymorphism rs75932628 with late-onset Alzheimer’s disease in Chinese Han population
- (2014) Jianfang Ma et al. NEUROLOGICAL RESEARCH
- Genetics of Alzheimer’s Disease
- (2014) Rita Guerreiro et al. Neurotherapeutics
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia
- (2013) Inna Belfer et al. AMERICAN JOURNAL OF HEMATOLOGY
- Distinctive patterns of DNA methylation associated with Parkinson disease
- (2013) Eliezer Masliah et al. Epigenetics
- Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population
- (2013) Hisashi Fukuda et al. JOURNAL OF HUMAN GENETICS
- Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis
- (2013) Kit Yee Chan et al. LANCET
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease
- (2013) Carlos Cruchaga et al. NEURON
- Racial and Ethnic Disparities in Alzheimer's Disease Pharmacotherapy Exposure: An Analysis Across Four State Medicaid Populations
- (2012) Adrienne M. Gilligan et al. American Journal Geriatric Pharmacotherapy
- Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase
- (2012) B. Detry et al. BLOOD
- Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes
- (2012) K. Okamoto et al. DIABETES
- Stratification-Score Matching Improves Correction for Confounding by Population Stratification in Case-Control Association Studies
- (2012) Michael P. Epstein et al. GENETIC EPIDEMIOLOGY
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies
- (2011) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Low-coverage sequencing: Implications for design of complex trait association studies
- (2011) Y. Li et al. GENOME RESEARCH
- Commentary on Functional analysis of APOE Locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE
- (2011) Minerva M Carrasquillo et al. JOURNAL OF HUMAN GENETICS
- APOE and Alzheimer disease: a major gene with semi-dominant inheritance
- (2011) E Genin et al. MOLECULAR PSYCHIATRY
- The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans
- (2010) Michael W. Weiner et al. Alzheimers & Dementia
- Identification of KCNJ15 as a Susceptibility Gene in Asian Patients with Type 2 Diabetes Mellitus
- (2010) Koji Okamoto et al. AMERICAN JOURNAL OF HUMAN GENETICS
- LocusZoom: regional visualization of genome-wide association scan results
- (2010) R. J. Pruim et al. BIOINFORMATICS
- Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort
- (2010) Li Shen et al. NEUROIMAGE
- A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals
- (2009) Brian L. Browning et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies
- (2009) Weihua Guan et al. GENETIC EPIDEMIOLOGY
- Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese
- (2009) Norihiro Takei et al. GENOMICS
- GCH1in early-onset Parkinson's disease
- (2009) Stephanie A. Cobb et al. MOVEMENT DISORDERS
- A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
- (2009) A D Roses et al. PHARMACOGENOMICS JOURNAL
- Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study
- (2008) Joseph H. Lee ARCHIVES OF NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started