Protein a resin lifetime study: Evaluation of protein a resin performance with a model-based approach in continuous capture

The role of more than 40 years of improvement in protein A chromatography in the growth of the therapeutic antibody industry

(2016) Glen R. Bolton et al.   BIOTECHNOLOGY PROGRESS

Conformational plasticity of IgG during protein A affinity chromatography

(2016) Pete Gagnon et al.   JOURNAL OF CHROMATOGRAPHY A

Mechanistic understanding of fouling of protein A chromatography resin

(2016) Mili Pathak et al.   JOURNAL OF CHROMATOGRAPHY A

Advance chromatin extraction improves capture performance of protein A affinity chromatography

(2016) Rui Nian et al.   JOURNAL OF CHROMATOGRAPHY A

In-column ATR-FTIR spectroscopy to monitor affinity chromatography purification of monoclonal antibodies

(2016) Maxime Boulet-Audet et al.   Scientific Reports

Structural and functional characteristics of virgin and fouled Protein A MabSelect resin cycled in a monoclonal antibody purification process

(2015) Shaojie Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A new, integrated, continuous purification process template for monoclonal antibodies: Process modeling and cost of goods studies

(2015) Alex Xenopoulos   JOURNAL OF BIOTECHNOLOGY

The business impact of an integrated continuous biomanufacturing platform for recombinant protein production

(2015) Jason Walther et al.   JOURNAL OF BIOTECHNOLOGY

Large-scale monoclonal antibody purification by continuous chromatography, from process design to scale-up

(2015) Valérie Girard et al.   JOURNAL OF BIOTECHNOLOGY

Effect of cleaning agents and additives on Protein A ligand degradation and chromatography performance

(2015) Lihua Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography

(2015) Monica Angarita et al.   JOURNAL OF CHROMATOGRAPHY A

White Paper on Continuous Bioprocessing May 20–21 2014 Continuous Manufacturing Symposium

(2015) Konstantin B. Konstantinov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity

(2014) Timothy M. Pabst et al.   JOURNAL OF CHROMATOGRAPHY A

High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells

(2014) Yvonne Genzel et al.   VACCINE

Design of high productivity sequential multi-column chromatography for antibody capture

(2013) Candy K.S. Ng et al.   FOOD AND BIOPRODUCTS PROCESSING

Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture

(2013) James Pollock et al.   JOURNAL OF CHROMATOGRAPHY A

Development and design of bio-pharmaceutical processes

(2013) Cleo Kontoravdi et al.   Current Opinion in Chemical Engineering

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

(2012) Catherine E.M. Hogwood et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Periodic counter-current chromatography - design and operational considerations for integrated and continuous purification of proteins

(2012) Rahul Godawat et al.   Biotechnology Journal

Improving affinity chromatography resin efficiency using semi-continuous chromatography

(2012) Ekta Mahajan et al.   JOURNAL OF CHROMATOGRAPHY A

Advances in the production and downstream processing of antibodies

(2011) John H. Chon et al.   New Biotechnology

mAbs

(2010) Pablo A. Scolnik   mAbs

Salt bridges: Geometrically specific, designable interactions

(2010) Jason E. Donald et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches

(2009) Davy Guillarme et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A theoretical study of continuous counter-current chromatography for adsorption isotherms with inflection points

(2009) Martin Ballerstein et al.   COMPUTERS & CHEMICAL ENGINEERING

Understanding ligand–protein interactions in affinity membrane chromatography for antibody purification

(2009) Cristiana Boi et al.   JOURNAL OF CHROMATOGRAPHY A

A mechanistic study of Protein A chromatography resin lifetime

(2009) Canping Jiang et al.   JOURNAL OF CHROMATOGRAPHY A

Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli

(2008) Usama Beshay et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Host cell protein clearance during protein a chromatography: Development of an improved column wash step

(2008) Abhinav A. Shukla et al.   BIOTECHNOLOGY PROGRESS

Diffusion of NaOH into a protein gel

(2008) Ruben Mercadé-Prieto et al.   CHEMICAL ENGINEERING SCIENCE

Design of fractional-order PIλDμ controllers with an improved differential evolution

(2008) Arijit Biswas et al.   ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE